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5IFW
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BU of 5ifw by Molmil
Quantitative interaction mapping reveals an extended ubiquitin regulatory domain in ASPL that disrupts functional p97 hexamers and induces cell death
Descriptor: ADENOSINE-5'-DIPHOSPHATE, Tether containing UBX domain for GLUT4, Transitional endoplasmic reticulum ATPase
Authors:Roske, Y, Heinemann, U.
Deposit date:2016-02-26
Release date:2016-10-26
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (3.4 Å)
Cite:Quantitative interaction mapping reveals an extended UBX domain in ASPL that disrupts functional p97 hexamers.
Nat Commun, 7, 2016
5L4G
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BU of 5l4g by Molmil
The human 26S proteasome at 3.9 A
Descriptor: 26S protease regulatory subunit 10B, 26S protease regulatory subunit 4, 26S protease regulatory subunit 6A, ...
Authors:Schweitzer, A, Aufderheide, A, Rudack, T, Beck, F.
Deposit date:2016-05-25
Release date:2016-09-07
Last modified:2024-05-08
Method:ELECTRON MICROSCOPY (3.9 Å)
Cite:Structure of the human 26S proteasome at a resolution of 3.9 angstrom.
Proc.Natl.Acad.Sci.USA, 113, 2016
5KNE
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BU of 5kne by Molmil
CryoEM Reconstruction of Hsp104 Hexamer
Descriptor: Heat shock protein 104, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER
Authors:Yokom, A.L, Gates, S.N, Jackrel, M.E, Mack, K.L, Su, M, Shorter, J, Southworth, D.R.
Deposit date:2016-06-28
Release date:2016-07-27
Last modified:2024-03-06
Method:ELECTRON MICROSCOPY (5.64 Å)
Cite:Spiral architecture of the Hsp104 disaggregase reveals the basis for polypeptide translocation.
Nat.Struct.Mol.Biol., 23, 2016
5WYK
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BU of 5wyk by Molmil
Cryo-EM structure of the 90S small subunit pre-ribosome (Mtr4-depleted, Enp1-TAP)
Descriptor: 13 kDa ribonucleoprotein-associated protein, 18S ribosomal RNA, 40S ribosomal protein S1-A, ...
Authors:Ye, K, Zhu, X, Sun, Q.
Deposit date:2017-01-13
Release date:2017-03-29
Last modified:2017-05-17
Method:ELECTRON MICROSCOPY (4.5 Å)
Cite:Molecular architecture of the 90S small subunit pre-ribosome.
Elife, 6, 2017
7CG3
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BU of 7cg3 by Molmil
Staggered ring conformation of CtHsp104 (Hsp104 from Chaetomium Thermophilum)
Descriptor: Heat shock protein 104
Authors:Inoue, Y, Hanazono, Y, Noi, K, Kawamoto, A, Kimatsuka, M, Harada, R, Takeda, K, Iwamasa, N, Shibata, K, Noguchi, K, Shigeta, Y, Namba, K, Ogura, T, Miki, K, Shinohara, K, Yohda, M.
Deposit date:2020-06-30
Release date:2021-04-28
Last modified:2024-05-29
Method:ELECTRON MICROSCOPY (5.1 Å)
Cite:Split conformation of Chaetomium thermophilum Hsp104 disaggregase.
Structure, 29, 2021
8R64
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BU of 8r64 by Molmil
Cryo-EM structure of the FIGNL1 AAA hexamer bound to RAD51
Descriptor: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, DNA repair protein RAD51 homolog 1, ...
Authors:Carver, A, Yates, L.A, Zhang, X.
Deposit date:2023-11-20
Release date:2024-09-04
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:Molecular basis of FIGNL1 in dissociating RAD51 from DNA and chromatin.
Biorxiv, 2024
8JUW
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BU of 8juw by Molmil
Human ATAD2 Walker B mutant-H3/H4K5Q complex, ATP state
Descriptor: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ATPase family AAA domain-containing protein 2
Authors:Cho, C, Song, J.
Deposit date:2023-06-27
Release date:2023-10-18
Method:ELECTRON MICROSCOPY (3.79 Å)
Cite:Structure of the human ATAD2 AAA+ histone chaperone reveals mechanism of regulation and inter-subunit communication.
Commun Biol, 6, 2023
8JUZ
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BU of 8juz by Molmil
Human ATAD2 Walker B mutant-H3/H4K5Q complex, ATP state (Class III)
Descriptor: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ATPase family AAA domain-containing protein 2
Authors:Cho, C, Song, J.
Deposit date:2023-06-27
Release date:2023-10-18
Method:ELECTRON MICROSCOPY (4.29 Å)
Cite:Structure of the human ATAD2 AAA+ histone chaperone reveals mechanism of regulation and inter-subunit communication.
Commun Biol, 6, 2023
8JUY
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BU of 8juy by Molmil
Human ATAD2 Walker B mutant-H3/H4K5Q complex, ATP state (Class II)
Descriptor: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ATPase family AAA domain-containing protein 2
Authors:Cho, C, Song, J.
Deposit date:2023-06-27
Release date:2023-10-18
Method:ELECTRON MICROSCOPY (4.34 Å)
Cite:Structure of the human ATAD2 AAA+ histone chaperone reveals mechanism of regulation and inter-subunit communication.
Commun Biol, 6, 2023
8K3Y
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BU of 8k3y by Molmil
The "5+1" heteromeric structure of Lon protease consisting of a spiral pentamer with Y224S mutation and an N-terminal-truncated monomeric E613K mutant
Descriptor: ADENOSINE-5'-DIPHOSPHATE, Lon protease
Authors:Li, S, Hsieh, K.Y, Kuo, C.I, Zhang, K, Chang, C.I.
Deposit date:2023-07-17
Release date:2023-10-25
Last modified:2023-11-29
Method:ELECTRON MICROSCOPY (4.42 Å)
Cite:A 5+1 assemble-to-activate mechanism of the Lon proteolytic machine.
Nat Commun, 14, 2023
5XMI
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BU of 5xmi by Molmil
Cryo-EM Structure of the ATP-bound VPS4 mutant-E233Q hexamer (masked)
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, Vacuolar protein sorting-associated protein 4
Authors:Sun, S, Li, L, Yang, F, Wang, X, Fan, F, Li, X, Wang, H, Sui, S.
Deposit date:2017-05-15
Release date:2017-08-09
Last modified:2024-03-27
Method:ELECTRON MICROSCOPY (3.9 Å)
Cite:Cryo-EM structures of the ATP-bound Vps4(E233Q) hexamer and its complex with Vta1 at near-atomic resolution
Nat Commun, 8, 2017
8RSB
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BU of 8rsb by Molmil
p97 (VCP) mutant - F539A ADP state
Descriptor: ADENOSINE-5'-DIPHOSPHATE, Transitional endoplasmic reticulum ATPase
Authors:Arie, M, Matzov, D, Karmona, R, Szenkier, N, Stanhill, A, Navon, A.
Deposit date:2024-01-24
Release date:2024-05-29
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:p97 (VCP) mutant - F539A ADP state
To Be Published
8RS9
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BU of 8rs9 by Molmil
p97 (VCP) double mutant - F266A F539A
Descriptor: Transitional endoplasmic reticulum ATPase
Authors:Arie, M, Matzov, D, Karmona, R, Szenkier, N, Stanhill, A, Navon, A.
Deposit date:2024-01-24
Release date:2024-05-29
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:p97 (VCP) double mutant - F266A F539A
To Be Published
8B5R
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BU of 8b5r by Molmil
p97-p37-SPI substrate complex
Descriptor: I3 sequence being threaded through the p97 channel, Protein phosphatase 1 regulatory subunit 7, Serine/threonine-protein phosphatase PP1-gamma catalytic subunit, ...
Authors:van den Boom, J, Marini, G, Meyer, H, Saibil, H.
Deposit date:2022-09-24
Release date:2023-06-07
Last modified:2024-07-24
Method:ELECTRON MICROSCOPY (6.1 Å)
Cite:Structural basis of ubiquitin-independent PP1 complex disassembly by p97.
Embo J., 42, 2023
8KG2
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BU of 8kg2 by Molmil
Crystal structure of p97-N/D1 hexamer in complex with FAF1-UBX domain
Descriptor: ADENOSINE-5'-DIPHOSPHATE, FAS-associated factor 1, Transitional endoplasmic reticulum ATPase
Authors:Kang, W.
Deposit date:2023-08-17
Release date:2024-05-29
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Crystal Structure of p97-N/D1 Hexamer Complexed with FAF1 UBX Domain
J. Korean Chem. Soc., 2024
8OOI
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BU of 8ooi by Molmil
Full composite cryo-EM map of p97/VCP in ADP.Pi state
Descriptor: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ...
Authors:Cheng, T.C, Sakata, E, Schuetz, A.K.
Deposit date:2023-04-05
Release date:2024-01-31
Last modified:2024-03-13
Method:ELECTRON MICROSCOPY (2.61 Å)
Cite:Characterizing ATP processing by the AAA+ protein p97 at the atomic level.
Nat.Chem., 16, 2024
8OJL
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BU of 8ojl by Molmil
Human Mitochondrial Lon Y394E Mutant ADP Bound
Descriptor: ADENOSINE-5'-DIPHOSPHATE, Lon protease homolog, mitochondrial
Authors:Kereiche, S, Bauer, J.A, Matyas, P, Novacek, J, Kutejova, E.
Deposit date:2023-03-24
Release date:2024-04-03
Last modified:2024-05-15
Method:ELECTRON MICROSCOPY (2.88 Å)
Cite:Polyphosphate and tyrosine phosphorylation in the N-terminal domain of the human mitochondrial Lon protease disrupts its functions.
Sci Rep, 14, 2024
8OM7
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BU of 8om7 by Molmil
Human Mitochondrial Lon Y186E Mutant ADP Bound
Descriptor: ADENOSINE-5'-DIPHOSPHATE, Lon protease homolog, mitochondrial
Authors:Kereiche, S, Bauer, J.A, Matyas, P, Novacek, J, Kutejova, E.
Deposit date:2023-03-31
Release date:2024-04-10
Last modified:2024-05-15
Method:ELECTRON MICROSCOPY (3.74 Å)
Cite:Polyphosphate and tyrosine phosphorylation in the N-terminal domain of the human mitochondrial Lon protease disrupts its functions.
Sci Rep, 14, 2024
8RHN
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BU of 8rhn by Molmil
Structure of the 55LCC ATPase complex
Descriptor: ATPase family gene 2 protein homolog A, ATPase family gene 2 protein homolog B, Cyclin-dependent kinase 2-interacting protein, ...
Authors:Foglizzo, M, Degtjarik, O, Zeqiraj, E.
Deposit date:2023-12-15
Release date:2024-03-27
Last modified:2024-05-08
Method:ELECTRON MICROSCOPY (4.5 Å)
Cite:The SPATA5-SPATA5L1 ATPase complex directs replisome proteostasis to ensure genome integrity.
Cell, 187, 2024
8OKA
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BU of 8oka by Molmil
Human Mitochondrial Lon Y394F Mutant ADP Bound
Descriptor: ADENOSINE-5'-DIPHOSPHATE, Lon protease homolog, mitochondrial
Authors:Kereiche, S, Bauer, J.A, Matyas, P, Novacek, J, Kutejova, E.
Deposit date:2023-03-28
Release date:2024-04-10
Last modified:2024-05-15
Method:ELECTRON MICROSCOPY (3.89 Å)
Cite:Polyphosphate and tyrosine phosphorylation in the N-terminal domain of the human mitochondrial Lon protease disrupts its functions.
Sci Rep, 14, 2024
8C0V
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BU of 8c0v by Molmil
Structure of the peroxisomal Pex1/Pex6 ATPase complex bound to a substrate in single seam state
Descriptor: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ...
Authors:Ruettermann, M, Koci, M, Lill, P, Geladas, E.D, Kaschani, F, Klink, B.U, Erdmann, R, Gatsogiannis, C.
Deposit date:2022-12-19
Release date:2023-10-04
Method:ELECTRON MICROSCOPY (4.1 Å)
Cite:Structure of the peroxisomal Pex1/Pex6 ATPase complex bound to a substrate.
Nat Commun, 14, 2023
8C0W
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BU of 8c0w by Molmil
Structure of the peroxisomal Pex1/Pex6 ATPase complex bound to a substrate in twin seam state
Descriptor: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ...
Authors:Ruettermann, M, Koci, M, Lill, P, Geladas, E.D, Kaschani, F, Klink, B.U, Erdmann, R, Gatsogiannis, C.
Deposit date:2022-12-19
Release date:2023-10-04
Method:ELECTRON MICROSCOPY (4.7 Å)
Cite:Structure of the peroxisomal Pex1/Pex6 ATPase complex bound to a substrate.
Nat Commun, 14, 2023
5Z6Q
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BU of 5z6q by Molmil
Crystal structure of AAA of Spastin
Descriptor: CHLORIDE ION, Spastin
Authors:Lin, Z, Wang, C, Shen, Y.
Deposit date:2018-01-25
Release date:2018-12-05
Last modified:2024-03-27
Method:X-RAY DIFFRACTION (3 Å)
Cite:The AAA protein spastin possesses two levels of basal ATPase activity
FEBS Lett., 592, 2018
5Z6R
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BU of 5z6r by Molmil
SPASTIN AAA WITH ATP
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, Spastin
Authors:Lin, Z, Wang, C, Shen, Y.
Deposit date:2018-01-25
Release date:2019-01-30
Last modified:2024-03-27
Method:X-RAY DIFFRACTION (3 Å)
Cite:The Aaa Family Protein Spastin Severs A Microtubule
To Be Published
8PQX
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BU of 8pqx by Molmil
p97 (VCP) mutant - F539A state III
Descriptor: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, Transitional endoplasmic reticulum ATPase
Authors:Arie, M, Matzov, D, Karmona, R, Szenkier, N, Stanhill, A, Navon, A.
Deposit date:2023-07-12
Release date:2024-05-29
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:p97 (VCP) mutant - F539A state III
To Be Published

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PDB entries from 2024-10-09

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