The human 26S proteasome at 3.9 A

This is a large structure.

Summary for 5L4G

EMDB information4002
DescriptorProteasome subunit alpha type-6, Proteasome subunit alpha type-2, Proteasome subunit alpha type-4, ... (23 entities in total)
Functional Keywordsproteostasis, aaa-atpase, hydrolase
Biological sourceHomo sapiens (Human)
Cellular locationCytoplasm  P60900 P25787 P25789 O14818 P28066 P25786 P25788 P20618 P49721 P49720 P28070 P28074 P28072 Q99436 P35998 P62191 P43686 P62333 P17980 P62195
Total number of polymer chains34
Total molecular weight1049264.89
Schweitzer, A.,Aufderheide, A.,Rudack, T.,Beck, F. (deposition date: 2016-05-25, release date: 2016-09-07, Last modification date: 2017-08-02)
Primary citation
Schweitzer, A.,Aufderheide, A.,Rudack, T.,Beck, F.,Pfeifer, G.,Plitzko, J.M.,Sakata, E.,Schulten, K.,Forster, F.,Baumeister, W.
Structure of the human 26S proteasome at a resolution of 3.9 angstrom.
Proc.Natl.Acad.Sci.USA, 113:7816-7821, 2016
PubMed: 27342858 (PDB entries with the same primary citation)
DOI: 10.1073/pnas.1608050113
MImport into Mendeley
Experimental method

Structure validation

ClashscoreRamachandran outliersSidechain outliers61.9%3.0%MetricValuePercentile RanksWorseBetterPercentile relative to all structuresPercentile relative to all EM structures

More Asymmetric unit images

Molmil generated image of 5l4g
no rotation
Molmil generated image of 5l4g
rotated about x axis by 90°
Molmil generated image of 5l4g
rotated about y axis by 90°