8R1P
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8R1N
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4Y7E
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![BU of 4y7e by Molmil](/molmil-images/mine/4y7e) | Crystal structure of beta-mannanase from Streptomyces thermolilacinus with mannohexaose | Descriptor: | CALCIUM ION, Endoglucanase, GLYCEROL, ... | Authors: | Kumagai, Y, Yamashita, K, Okuyama, M, Hatanaka, T, Yao, M, Kimura, A. | Deposit date: | 2015-02-14 | Release date: | 2015-09-23 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | The loop structure of Actinomycete glycoside hydrolase family 5 mannanases governs substrate recognition Febs J., 282, 2015
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8QNB
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![BU of 8qnb by Molmil](/molmil-images/mine/8qnb) | Crystal structure of ancestral L-galactono-1,4-lactone dehydrogenase: in complex with L-galactono-1,4-lactone | Descriptor: | FLAVIN-ADENINE DINUCLEOTIDE, L-galactono-1,4-lactone, L-galactono-1,4-lactone dehydrogenase | Authors: | Boverio, A, Mattevi, A. | Deposit date: | 2023-09-26 | Release date: | 2024-05-01 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Crystal structure of ancestral L-galactono-1,4-lactone dehydrogenase: in complex with L-galactono-1,4-lactone To Be Published
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8QNC
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6ZJU
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![BU of 6zju by Molmil](/molmil-images/mine/6zju) | Cold-adapted beta-D-galactosidase from Arthrobacter sp. 32cB mutant E441Q in complex with saccharose | Descriptor: | ACETATE ION, Beta-galactosidase, MALONATE ION, ... | Authors: | Rutkiewicz, M, Bujacz, A, Bujacz, G. | Deposit date: | 2020-06-29 | Release date: | 2020-08-05 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (1.75 Å) | Cite: | Mapping the Transglycosylation Relevant Sites of Cold-Adapted beta-d-Galactosidase fromArthrobactersp. 32cB. Int J Mol Sci, 21, 2020
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8R4B
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8QMH
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![BU of 8qmh by Molmil](/molmil-images/mine/8qmh) | Crystal structure of RNA G2C4 repeats in complex with small synthetic molecule ANP77 | Descriptor: | 3-(7-azanyl-1,8-naphthyridin-2-yl)-2-[(7-azanyl-1,8-naphthyridin-2-yl)methyl]-~{N}-(3-azanylpropyl)propanamide, CHLORIDE ION, RNA (5'-R(*GP*GP*CP*CP*CP*C)-3') | Authors: | Kiliszek, A, Ryczek, M, Blaszczyk, L. | Deposit date: | 2023-09-22 | Release date: | 2024-05-01 | Last modified: | 2024-07-03 | Method: | X-RAY DIFFRACTION (1.1 Å) | Cite: | Antisense RNA C9orf72 hexanucleotide repeat associated with amyotrophic lateral sclerosis and frontotemporal dementia forms a triplex-like structure and binds small synthetic ligand. Nucleic Acids Res., 52, 2024
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1AA1
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8RHL
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![BU of 8rhl by Molmil](/molmil-images/mine/8rhl) | Yeast 20S proteasome in complex with a linear biarylether epoxyketone (compound 15a) | Descriptor: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CHLORIDE ION, Linear biarylether epoxyketone, ... | Authors: | Goetz, M.G, Godwin, K, Price, R, Dorn, R, Merrill-Steskal, G, Hansen, H, Klemmer, W, Produturi, G, Rocha, M, Palmer, M, Molacek, L, Strater, Z, Groll, M. | Deposit date: | 2023-12-15 | Release date: | 2024-05-01 | Method: | X-RAY DIFFRACTION (3.2 Å) | Cite: | Macrocyclic Oxindole Peptide Epoxyketones-A Comparative Study of Macrocyclic Inhibitors of the 20S Proteasome. Acs Med.Chem.Lett., 15, 2024
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8QMY
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8R18
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![BU of 8r18 by Molmil](/molmil-images/mine/8r18) | Pim1 in complex with (E)-4-(4-hydroxystyryl)benzoic acid and Pimtide | Descriptor: | (E)-4-(4-hydroxystyryl)benzoic acid, 1,2-ETHANEDIOL, GLYCEROL, ... | Authors: | Hochban, P.M.M, Heine, A, Diederich, W.E. | Deposit date: | 2023-11-01 | Release date: | 2024-03-20 | Last modified: | 2024-06-12 | Method: | X-RAY DIFFRACTION (1.89 Å) | Cite: | What doesn't fit is made to fit: Pim-1 kinase adapts to the configuration of stilbene-based inhibitors. Arch Pharm, 357, 2024
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7ZVB
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![BU of 7zvb by Molmil](/molmil-images/mine/7zvb) | Crystal Structure of the mature form of the glutamic-class prolyl-endopeptidase neprosin at 2.35 A resolution. | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, C-terminal peptidase, TRIETHYLENE GLYCOL, ... | Authors: | Del Amo-Maestro, L, Eckhard, U, Rodriguez-Banqueri, A, Mendes, S.R, Guevara, T, Gomis-Ruth, F.X. | Deposit date: | 2022-05-14 | Release date: | 2022-08-10 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (2.35 Å) | Cite: | Molecular and in vivo studies of a glutamate-class prolyl-endopeptidase for coeliac disease therapy. Nat Commun, 13, 2022
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8R10
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8QOA
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![BU of 8qoa by Molmil](/molmil-images/mine/8qoa) | Structure of SecM-stalled Escherichia coli 70S ribosome | Descriptor: | 16S rRNA, 23S rRNA, 30S ribosomal protein S16, ... | Authors: | Gersteuer, F, Morici, M, Wilson, D.N. | Deposit date: | 2023-09-28 | Release date: | 2024-03-20 | Last modified: | 2024-04-24 | Method: | ELECTRON MICROSCOPY (2 Å) | Cite: | The SecM arrest peptide traps a pre-peptide bond formation state of the ribosome. Nat Commun, 15, 2024
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8R4D
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8RHK
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![BU of 8rhk by Molmil](/molmil-images/mine/8rhk) | Yeast 20S proteasome in complex with a linear oxindole epoxyketone (compound 6) | Descriptor: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CHLORIDE ION, Linear oxindole epoxyketone, ... | Authors: | Goetz, M.G, Godwin, K, Price, R, Dorn, R, Merrill-Steskal, G, Hansen, H, Klemmer, W, Produturi, G, Rocha, M, Palmer, M, Molacek, L, Strater, Z, Groll, M. | Deposit date: | 2023-12-15 | Release date: | 2024-05-01 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Macrocyclic Oxindole Peptide Epoxyketones-A Comparative Study of Macrocyclic Inhibitors of the 20S Proteasome. Acs Med.Chem.Lett., 15, 2024
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8R1J
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![BU of 8r1j by Molmil](/molmil-images/mine/8r1j) | Structure of avian H5N1 influenza A polymerase dimer in complex with human ANP32B. | Descriptor: | Acidic leucine-rich nuclear phosphoprotein 32 family member B, Polymerase acidic protein, Polymerase basic protein 2, ... | Authors: | Carrique, L, Staller, E, Keown, J.R, Fan, H, Fodor, E, Grimes, J.M. | Deposit date: | 2023-11-02 | Release date: | 2024-05-08 | Last modified: | 2024-05-29 | Method: | ELECTRON MICROSCOPY (3.2 Å) | Cite: | Structures of H5N1 influenza polymerase with ANP32B reveal mechanisms of genome replication and host adaptation. Nat Commun, 15, 2024
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8ROO
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![BU of 8roo by Molmil](/molmil-images/mine/8roo) | Crystal structure of HLA B*18:01 in complex with YERMCNIL, an 8-mer epitope from Influenza A | Descriptor: | 1,2-ETHANEDIOL, Beta-2-microglobulin, Influenza A derived peptide/Nucleoprotein, ... | Authors: | Murdolo, L.D, Maddumage, J.C, Gras, S. | Deposit date: | 2024-01-11 | Release date: | 2024-05-08 | Last modified: | 2024-07-24 | Method: | X-RAY DIFFRACTION (1.4 Å) | Cite: | Characterisation of novel influenza-derived HLA-B*18:01-restricted epitopes. Clin Transl Immunology, 13, 2024
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6ZDX
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![BU of 6zdx by Molmil](/molmil-images/mine/6zdx) | RIFIN variable region bound to LILRB1 ectodomain | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Leukocyte immunoglobulin-like receptor subfamily B member 1, ... | Authors: | Harrison, T.E, Higgins, M.K. | Deposit date: | 2020-06-15 | Release date: | 2020-07-22 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Structural basis for RIFIN-mediated activation of LILRB1 in malaria. Nature, 587, 2020
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8R80
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![BU of 8r80 by Molmil](/molmil-images/mine/8r80) | SARS-CoV-2 Delta RBD in complex with XBB-9 Fab and an anti-Fab nanobody | Descriptor: | Spike protein S1, XBB-9 Fab heavy chain, XBB-9 Fab light chain, ... | Authors: | Zhou, D, Ren, J, Stuart, D.I. | Deposit date: | 2023-11-27 | Release date: | 2024-05-08 | Last modified: | 2024-06-05 | Method: | X-RAY DIFFRACTION (4.03 Å) | Cite: | A structure-function analysis shows SARS-CoV-2 BA.2.86 balances antibody escape and ACE2 affinity. Cell Rep Med, 5, 2024
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8ROP
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![BU of 8rop by Molmil](/molmil-images/mine/8rop) | Crystal structure of HLA B*18:01 in complex with QEIRTFSF, an 8-mer epitope from Influenza A | Descriptor: | 1,2-ETHANEDIOL, Beta-2-microglobulin, CHLORIDE ION, ... | Authors: | Murdolo, L.D, Maddumage, J.C, Gras, S. | Deposit date: | 2024-01-12 | Release date: | 2024-05-08 | Last modified: | 2024-07-24 | Method: | X-RAY DIFFRACTION (1.15 Å) | Cite: | Characterisation of novel influenza-derived HLA-B*18:01-restricted epitopes. Clin Transl Immunology, 13, 2024
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8QTD
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![BU of 8qtd by Molmil](/molmil-images/mine/8qtd) | Local refinement of SARS-CoV-2 BA.2.86 Spike and XBB-7 Fab | Descriptor: | Spike glycoprotein,Fibritin, XBB-7 fab heavy chain, XBB-7 fab light chain | Authors: | Ren, J, Duyvesteyn, H.M.E, Stuart, D.I. | Deposit date: | 2023-10-12 | Release date: | 2024-05-08 | Last modified: | 2024-06-05 | Method: | ELECTRON MICROSCOPY (3.6 Å) | Cite: | A structure-function analysis shows SARS-CoV-2 BA.2.86 balances antibody escape and ACE2 affinity. Cell Rep Med, 5, 2024
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8QPA
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![BU of 8qpa by Molmil](/molmil-images/mine/8qpa) | Cryo-EM Structure of Pre-B+5'ssLNG Complex (core part) | Descriptor: | 116 kDa U5 small nuclear ribonucleoprotein component, 5'ss oligo, INOSITOL HEXAKISPHOSPHATE, ... | Authors: | Zhang, Z, Kumar, V, Dybkov, O, Will, C.L, Zhong, J, Ludwig, S, Urlaub, H, Kastner, B, Stark, H, Luehrmann, R. | Deposit date: | 2023-10-01 | Release date: | 2024-05-22 | Last modified: | 2024-07-10 | Method: | ELECTRON MICROSCOPY (3.7 Å) | Cite: | Structural insights into the cross-exon to cross-intron spliceosome switch. Nature, 630, 2024
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8QPK
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![BU of 8qpk by Molmil](/molmil-images/mine/8qpk) | Cryo-EM Structure of Pre-B+5'ss Complex (core part) | Descriptor: | 116 kDa U5 small nuclear ribonucleoprotein component, 5'ss oligo, INOSITOL HEXAKISPHOSPHATE, ... | Authors: | Zhang, Z, Kumar, V, Dybkov, O, Will, C.L, Zhong, J, Ludwig, S, Urlaub, H, Kastner, B, Stark, H, Luehrmann, R. | Deposit date: | 2023-10-02 | Release date: | 2024-05-22 | Last modified: | 2024-07-10 | Method: | ELECTRON MICROSCOPY (4.2 Å) | Cite: | Structural insights into the cross-exon to cross-intron spliceosome switch. Nature, 630, 2024
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