8R80

SARS-CoV-2 Delta RBD in complex with XBB-9 Fab and an anti-Fab nanobody

Summary for 8R80

• Entry DOI: 10.2210/pdb8r80/pdb
• Related: 8QRF 8QRG 8QSQ 8QTD
• Descriptor: XBB-9 Fab heavy chain, XBB-9 Fab light chain, Spike protein S1, ... (4 entities in total)
• Functional Keywords: sars-cov-2, rbd, ba.2.86, xbb.1.5, xbb.1.5.10, xbb.1.5.70, viral protein
• Biological source: Homo sapiens; More
• Total number of polymer chains: 8
• Total formula weight: 169573.34

Authors

Zhou, D.,Ren, J.,Stuart, D.I. (deposition date: 2023-11-27, release date: 2024-05-08, Last modification date: 2024-06-05)

• Primary citation: Liu, C.,Zhou, D.,Dijokaite-Guraliuc, A.,Supasa, P.,Duyvesteyn, H.M.E.,Ginn, H.M.,Selvaraj, M.,Mentzer, A.J.,Das, R.,de Silva, T.I.,Ritter, T.G.,Plowright, M.,Newman, T.A.H.,Stafford, L.,Kronsteiner, B.,Temperton, N.,Lui, Y.,Fellermeyer, M.,Goulder, P.,Klenerman, P.,Dunachie, S.J.,Barton, M.I.,Kutuzov, M.A.,Dushek, O.,Fry, E.E.,Mongkolsapaya, J.,Ren, J.,Stuart, D.I.,Screaton, G.R.; A structure-function analysis shows SARS-CoV-2 BA.2.86 balances antibody escape and ACE2 affinity.; Cell Rep Med, 5:101553-101553, 2024; PubMed: 38723626; DOI: 10.1016/j.xcrm.2024.101553

Experimental method

X-RAY DIFFRACTION (4.03 Å)