7TJQ
 
 | | SAN27-14 bound to a antigenic site V on prefusion-stabilized hMPV F | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Fusion glycoprotein F0, MPE8 Fab heavy chain, ... | | Authors: | Hsieh, C.-L, McLellan, J.S, Rush, S.A. | | Deposit date: | 2022-01-16 | | Release date: | 2022-09-14 | | Last modified: | 2022-11-23 | | Method: | ELECTRON MICROSCOPY (3.13 Å) | | Cite: | Characterization of prefusion-F-specific antibodies elicited by natural infection with human metapneumovirus.
Cell Rep, 40, 2022
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8PDY
 | | E. coli RNA polymerase paused at ops site | | Descriptor: | DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ... | | Authors: | Zuber, P.K, Said, N, Hilal, T, Loll, B, Wahl, M.C, Knauer, S.H. | | Deposit date: | 2023-06-13 | | Release date: | 2024-04-24 | | Method: | ELECTRON MICROSCOPY (2.8 Å) | | Cite: | Concerted transformation of a hyper-paused transcription complex and its reinforcing protein.
Nat Commun, 15, 2024
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8QOI
 | | Structure of the human 80S ribosome at 1.9 A resolution - the molecular role of chemical modifications and ions in RNA | | Descriptor: | 18S rRNA (1740-MER), 28S rRNA (3773-MER), 40S ribosomal protein S10, ... | | Authors: | Holvec, S, Barchet, C, Frechin, L, Hazemann, I, von Loeffelholz, O, Klaholz, B.P. | | Deposit date: | 2023-09-29 | | Release date: | 2024-06-12 | | Last modified: | 2024-08-28 | | Method: | ELECTRON MICROSCOPY (1.9 Å) | | Cite: | The structure of the human 80S ribosome at 1.9 angstrom resolution reveals the molecular role of chemical modifications and ions in RNA.
Nat.Struct.Mol.Biol., 31, 2024
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7L5W
 | | p97-R155H mutant dodecamer I | | Descriptor: | Transitional endoplasmic reticulum ATPase | | Authors: | Nandi, P, Li, S, Coulmbres, R.C.A, Wang, F, Williams, D.R, Malyutin, A.G, Poh, Y.-P, Chou, T.-F, Chiu, P.-L. | | Deposit date: | 2020-12-23 | | Release date: | 2021-08-04 | | Last modified: | 2024-05-29 | | Method: | ELECTRON MICROSCOPY (3.34 Å) | | Cite: | Structural and Functional Analysis of Disease-Linked p97 ATPase Mutant Complexes.
Int J Mol Sci, 22, 2021
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7MWD
 | | HUWE1 in map with focus on HECT | | Descriptor: | E3 ubiquitin-protein ligase HUWE1 | | Authors: | Hunkeler, M, Fischer, E.S. | | Deposit date: | 2021-05-16 | | Release date: | 2021-07-28 | | Last modified: | 2024-05-29 | | Method: | ELECTRON MICROSCOPY (3.7 Å) | | Cite: | Solenoid architecture of HUWE1 contributes to ligase activity and substrate recognition.
Mol.Cell, 81, 2021
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7M99
 | | ATPgS bound TnsC filament from ShCAST system | | Descriptor: | DNA (5'-D(P*AP*AP*AP*AP*AP*AP*AP*AP*AP*AP*AP*AP*AP*AP*AP*AP*AP*AP*A)-3'), DNA (5'-D(P*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*T)-3'), MAGNESIUM ION, ... | | Authors: | Park, J, Tsai, A.W.L, Mehrotra, E, Kellogg, E.H. | | Deposit date: | 2021-03-30 | | Release date: | 2021-07-28 | | Last modified: | 2024-05-29 | | Method: | ELECTRON MICROSCOPY (3.2 Å) | | Cite: | Structural basis for target site selection in RNA-guided DNA transposition systems.
Science, 373, 2021
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7MWF
 | | HUWE1 in map with focus on interface | | Descriptor: | E3 ubiquitin-protein ligase HUWE1 | | Authors: | Hunkeler, M, Fischer, E.S. | | Deposit date: | 2021-05-16 | | Release date: | 2021-07-28 | | Last modified: | 2024-05-29 | | Method: | ELECTRON MICROSCOPY (3.3 Å) | | Cite: | Solenoid architecture of HUWE1 contributes to ligase activity and substrate recognition.
Mol.Cell, 81, 2021
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7MOP
 | | Cryo-EM structure of human HUWE1 in complex with DDIT4 | | Descriptor: | DNA damage-inducible transcript 4 protein, E3 ubiquitin-protein ligase HUWE1 | | Authors: | Hunkeler, M, Fischer, E.S. | | Deposit date: | 2021-05-03 | | Release date: | 2021-07-28 | | Last modified: | 2024-05-29 | | Method: | ELECTRON MICROSCOPY (3.3 Å) | | Cite: | Solenoid architecture of HUWE1 contributes to ligase activity and substrate recognition.
Mol.Cell, 81, 2021
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7MWE
 | | HUWE1 in map with focus on WWE | | Descriptor: | E3 ubiquitin-protein ligase HUWE1 | | Authors: | Hunkeler, M, Fischer, E.S. | | Deposit date: | 2021-05-16 | | Release date: | 2021-07-28 | | Last modified: | 2024-05-29 | | Method: | ELECTRON MICROSCOPY (3.4 Å) | | Cite: | Solenoid architecture of HUWE1 contributes to ligase activity and substrate recognition.
Mol.Cell, 81, 2021
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7KOG
 | | Lethocerus Myosin II complete coiled-coil domain resolved in its native environment | | Descriptor: | Myosin heavy chain isoform Mhc_X1 | | Authors: | Rahmani, H, Hu, Z, Daneshparvar, N, Taylor, D, Taylor, K.A. | | Deposit date: | 2020-11-09 | | Release date: | 2021-03-24 | | Last modified: | 2024-05-29 | | Method: | ELECTRON MICROSCOPY (4.25 Å) | | Cite: | The myosin II coiled-coil domain atomic structure in its native environment.
Proc.Natl.Acad.Sci.USA, 118, 2021
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8VRC
 | | Tetrahymena thermophila MLP1 RRM domain | | Descriptor: | LA motif RNA-binding domain protein | | Authors: | Donaldson, L.W. | | Deposit date: | 2024-01-21 | | Release date: | 2024-09-04 | | Method: | SOLUTION NMR | | Cite: | NMR structure of the second RNA binding domain from Tetrahymena thermophila Mlp1
To Be Published
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8S9S
 | | Structure of the human ER membrane protein complex (EMC) in GDN | | Descriptor: | 1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | Authors: | Tomaleri, G.P, Nguyen, V.N, Voorhees, R.M. | | Deposit date: | 2023-03-30 | | Release date: | 2023-05-17 | | Last modified: | 2023-06-14 | | Method: | ELECTRON MICROSCOPY (3.6 Å) | | Cite: | A selectivity filter in the ER membrane protein complex limits protein misinsertion at the ER.
J.Cell Biol., 222, 2023
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8SL0
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8G2M
 | | The tumor activated anti-CTLA-4 monoclonal antibody XTX101 demonstrates tumor-growth inhibition and tumor-selective pharmacodynamics in mouse models of cancer | | Descriptor: | CITRIC ACID, Heavy chain of humanized IgG, Light chain of humanized IgG, ... | | Authors: | Williams, J.C, Williams, J.C. | | Deposit date: | 2023-02-05 | | Release date: | 2024-02-14 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | XTX101, a tumor-activated, Fc-enhanced anti-CTLA-4 monoclonal antibody, demonstrates tumor-growth inhibition and tumor-selective pharmacodynamics in mouse models of cancer.
J Immunother Cancer, 11, 2023
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8SDK
 | | The MicroED structure of proteinase K crystallized by suspended drop crystallization | | Descriptor: | CALCIUM ION, Proteinase K, SULFATE ION | | Authors: | Gillman, C, Nicolas, W.J, Martynowycz, M.W, Gonen, T. | | Deposit date: | 2023-04-06 | | Release date: | 2023-05-31 | | Last modified: | 2023-07-12 | | Method: | ELECTRON CRYSTALLOGRAPHY (2.1 Å) | | Cite: | Design and implementation of suspended drop crystallization.
Iucrj, 10, 2023
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8SLY
 | | Rat TRPV2 bound with 2 CBD ligands in nanodiscs | | Descriptor: | (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, SODIUM ION, Transient receptor potential cation channel subfamily V member 2, ... | | Authors: | Tan, X, Swartz, K.J. | | Deposit date: | 2023-04-24 | | Release date: | 2023-05-31 | | Last modified: | 2024-06-19 | | Method: | ELECTRON MICROSCOPY (3.32 Å) | | Cite: | Cannabidiol sensitizes TRPV2 channels to activation by 2-APB.
Elife, 12, 2023
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8SLX
 | | Rat TRPV2 bound with 1 CBD ligand in nanodiscs | | Descriptor: | SODIUM ION, Transient receptor potential cation channel subfamily V member 2, cannabidiol | | Authors: | Tan, X, Swartz, K.J. | | Deposit date: | 2023-04-24 | | Release date: | 2023-05-31 | | Last modified: | 2024-06-19 | | Method: | ELECTRON MICROSCOPY (3.23 Å) | | Cite: | Cannabidiol sensitizes TRPV2 channels to activation by 2-APB.
Elife, 12, 2023
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8GTR
 | | CryoEM structure of human Pannexin isoform 3 | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, PHOSPHATIDYLETHANOLAMINE, Pannexin-3 | | Authors: | Hussain, N, Penmatsa, A. | | Deposit date: | 2022-09-08 | | Release date: | 2024-02-28 | | Last modified: | 2024-06-19 | | Method: | ELECTRON MICROSCOPY (3.91 Å) | | Cite: | Cryo-EM structures of pannexin 1 and 3 reveal differences among pannexin isoforms.
Nat Commun, 15, 2024
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8GTT
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8G9S
 | | Exploiting Activation and Inactivation Mechanisms in Type I-C CRISPR-Cas3 for Genome Editing Applications | | Descriptor: | AcrIC8, Cas11, Cas5, ... | | Authors: | Hu, C, Nam, K.H, Ke, A. | | Deposit date: | 2023-02-22 | | Release date: | 2024-03-06 | | Method: | ELECTRON MICROSCOPY (3.4 Å) | | Cite: | Exploiting activation and inactivation mechanisms in type I-C CRISPR-Cas3 for genome-editing applications.
Mol.Cell, 84, 2024
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8G9U
 | | Exploiting Activation and Inactivation Mechanisms in Type I-C CRISPR-Cas3 for Genome Editing Applications | | Descriptor: | CRISPR-associated protein, Csd1 family, Csd2 family, ... | | Authors: | Hu, C, Nam, K.H, Ke, A. | | Deposit date: | 2023-02-22 | | Release date: | 2024-03-06 | | Method: | ELECTRON MICROSCOPY (3 Å) | | Cite: | Exploiting activation and inactivation mechanisms in type I-C CRISPR-Cas3 for genome-editing applications.
Mol.Cell, 84, 2024
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8GM3
 | | Vibrio harveyi Holo HphA | | Descriptor: | HEME B/C, Hemophilin | | Authors: | Pan, C, Shah, M, Moraes, T.F. | | Deposit date: | 2023-03-24 | | Release date: | 2024-03-27 | | Last modified: | 2024-07-03 | | Method: | X-RAY DIFFRACTION (1.727 Å) | | Cite: | Prevalence of Slam-dependent hemophilins in Gram-negative bacteria.
J.Bacteriol., 206, 2024
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8GLO
 | | Haemophilus parainfluenzae Holo HphA | | Descriptor: | CHLORIDE ION, HEME B/C, Hemophilin | | Authors: | Shin, H.E, Ng, D, Moraes, T.F. | | Deposit date: | 2023-03-22 | | Release date: | 2024-03-27 | | Last modified: | 2024-07-03 | | Method: | X-RAY DIFFRACTION (1.937 Å) | | Cite: | Prevalence of Slam-dependent hemophilins in Gram-negative bacteria.
J.Bacteriol., 206, 2024
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8ST7
 | | Structure of E3 ligase VsHECT bound to ubiquitin | | Descriptor: | E3 ubiquitin-protein ligase SopA-like catalytic domain-containing protein, Ubiquitin, prop-2-en-1-amine | | Authors: | Franklin, T.G, Pruneda, J.N. | | Deposit date: | 2023-05-09 | | Release date: | 2023-07-12 | | Last modified: | 2024-01-03 | | Method: | X-RAY DIFFRACTION (1.44 Å) | | Cite: | Bacterial ligases reveal fundamental principles of polyubiquitin specificity.
Mol.Cell, 83, 2023
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8ST8
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