7MWD

HUWE1 in map with focus on HECT

Summary for 7MWD

Entry DOI	10.2210/pdb7mwd/pdb
Related	7JQ9 7MOP
EMDB information	22427 22428 22429 22430 22431 23925 23931
Descriptor	E3 ubiquitin-protein ligase HUWE1 (1 entity in total)
Functional Keywords	ubiquitin, quality control, e3 ligase, protein degradation, transferase
Biological source	Homo sapiens (Human)
Total number of polymer chains	1
Total formula weight	486409.53
Authors	Hunkeler, M.,Fischer, E.S. (deposition date: 2021-05-16, release date: 2021-07-28, Last modification date: 2021-09-15)
Primary citation	Hunkeler, M.,Jin, C.Y.,Ma, M.W.,Monda, J.K.,Overwijn, D.,Bennett, E.J.,Fischer, E.S. Solenoid architecture of HUWE1 contributes to ligase activity and substrate recognition. Mol.Cell, 81:3468-, 2021 Cited by PubMed: 34314700 DOI: 10.1016/j.molcel.2021.06.032 PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (3.7 Å)

Structure validation