8S9S

Structure of the human ER membrane protein complex (EMC) in GDN

This is a non-PDB format compatible entry.

Summary for 8S9S

• Entry DOI: 10.2210/pdb8s9s/pdb
• EMDB information: 40245
• Descriptor: ER membrane protein complex subunit 1, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... (12 entities in total)
• Functional Keywords: insertase, endoplasmic reticulum, transmembrane chaperone, membrane protein
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 9
• Total formula weight: 307492.80

Authors

Tomaleri, G.P.,Nguyen, V.N.,Voorhees, R.M. (deposition date: 2023-03-30, release date: 2023-05-17, Last modification date: 2023-06-14)

• Primary citation: Pleiner, T.,Hazu, M.,Pinton Tomaleri, G.,Nguyen, V.N.,Januszyk, K.,Voorhees, R.M.; A selectivity filter in the ER membrane protein complex limits protein misinsertion at the ER.; J.Cell Biol., 222:-, 2023; PubMed: 37199759; DOI: 10.1083/jcb.202212007

Experimental method

ELECTRON MICROSCOPY (3.6 Å)