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8S9S

Structure of the human ER membrane protein complex (EMC) in GDN

This is a non-PDB format compatible entry.
Functional Information from GO Data
ChainGOidnamespacecontents
10072546cellular_componentEMC complex
20005515molecular_functionprotein binding
20005737cellular_componentcytoplasm
20005783cellular_componentendoplasmic reticulum
20005789cellular_componentendoplasmic reticulum membrane
20016020cellular_componentmembrane
20032977molecular_functionmembrane insertase activity
20042406cellular_componentextrinsic component of endoplasmic reticulum membrane
20045050biological_processprotein insertion into ER membrane by stop-transfer membrane-anchor sequence
20071816biological_processtail-anchored membrane protein insertion into ER membrane
20072546cellular_componentEMC complex
30005515molecular_functionprotein binding
30005783cellular_componentendoplasmic reticulum
30005789cellular_componentendoplasmic reticulum membrane
30016020cellular_componentmembrane
30032977molecular_functionmembrane insertase activity
30045050biological_processprotein insertion into ER membrane by stop-transfer membrane-anchor sequence
30071816biological_processtail-anchored membrane protein insertion into ER membrane
30072546cellular_componentEMC complex
40005515molecular_functionprotein binding
40005783cellular_componentendoplasmic reticulum
40005789cellular_componentendoplasmic reticulum membrane
40006915biological_processapoptotic process
40016020cellular_componentmembrane
40032977molecular_functionmembrane insertase activity
40045050biological_processprotein insertion into ER membrane by stop-transfer membrane-anchor sequence
40071816biological_processtail-anchored membrane protein insertion into ER membrane
40072546cellular_componentEMC complex
50000139cellular_componentGolgi membrane
50005515molecular_functionprotein binding
50005737cellular_componentcytoplasm
50005768cellular_componentendosome
50005769cellular_componentearly endosome
50005783cellular_componentendoplasmic reticulum
50005789cellular_componentendoplasmic reticulum membrane
50005794cellular_componentGolgi apparatus
50005886cellular_componentplasma membrane
50006812biological_processmonoatomic cation transport
50006824biological_processcobalt ion transport
50006825biological_processcopper ion transport
50006826biological_processiron ion transport
50015087molecular_functioncobalt ion transmembrane transporter activity
50015093molecular_functionferrous iron transmembrane transporter activity
50015095molecular_functionmagnesium ion transmembrane transporter activity
50015693biological_processmagnesium ion transport
50016020cellular_componentmembrane
50022890molecular_functioninorganic cation transmembrane transporter activity
50031901cellular_componentearly endosome membrane
50032977molecular_functionmembrane insertase activity
50034755biological_processiron ion transmembrane transport
50043231cellular_componentintracellular membrane-bounded organelle
50045050biological_processprotein insertion into ER membrane by stop-transfer membrane-anchor sequence
50071816biological_processtail-anchored membrane protein insertion into ER membrane
50072546cellular_componentEMC complex
51903830biological_processmagnesium ion transmembrane transport
60000045biological_processautophagosome assembly
60005515molecular_functionprotein binding
60005783cellular_componentendoplasmic reticulum
60005789cellular_componentendoplasmic reticulum membrane
60016020cellular_componentmembrane
60032977molecular_functionmembrane insertase activity
60045050biological_processprotein insertion into ER membrane by stop-transfer membrane-anchor sequence
60071816biological_processtail-anchored membrane protein insertion into ER membrane
60072546cellular_componentEMC complex
61903349cellular_componentomegasome membrane
70030246molecular_functioncarbohydrate binding
80005515molecular_functionprotein binding
80005737cellular_componentcytoplasm
80005783cellular_componentendoplasmic reticulum
80005789cellular_componentendoplasmic reticulum membrane
80005794cellular_componentGolgi apparatus
80016020cellular_componentmembrane
80032977molecular_functionmembrane insertase activity
80045050biological_processprotein insertion into ER membrane by stop-transfer membrane-anchor sequence
80071816biological_processtail-anchored membrane protein insertion into ER membrane
80072546cellular_componentEMC complex
Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues195
DetailsTOPO_DOM: Lumenal => ECO:0000269|PubMed:32439656
ChainResidueDetails
10ARG26-SER221
6ARG72-LEU89

site_idSWS_FT_FI2
Number of Residues20
DetailsTRANSMEM: Helical => ECO:0000255
ChainResidueDetails
10PHE222-ALA242
6GLY51-GLY71
6ILE90-MET106

site_idSWS_FT_FI3
Number of Residues19
DetailsTOPO_DOM: Cytoplasmic => ECO:0000269|PubMed:32439656
ChainResidueDetails
10PRO243-ARG262
6VAL107-TYR110

site_idSWS_FT_FI4
Number of Residues1
DetailsCARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000269|PubMed:19159218, ECO:0000269|PubMed:32439656
ChainResidueDetails
10ASN182
1ASN818

site_idSWS_FT_FI5
Number of Residues1
DetailsMOD_RES: Phosphoserine => ECO:0007744|PubMed:23186163, ECO:0007744|PubMed:24275569
ChainResidueDetails
4SER36

227561

PDB entries from 2024-11-20

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