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6ENG
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BU of 6eng by Molmil
Crystal structure of the 43K ATPase domain of Escherichia coli gyrase B in complex with an aminocoumarin
Descriptor: CHLORIDE ION, Coumermycin A1, DNA gyrase subunit B, ...
Authors:Vanden Broeck, A, McEwen, A.G, Lamour, V.
Deposit date:2017-10-04
Release date:2019-04-10
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structural Basis for DNA Gyrase Interaction with Coumermycin A1.
J.Med.Chem., 62, 2019
8QJ4
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BU of 8qj4 by Molmil
Receptor Sd-Amt1 (ON-state)
Descriptor: AMMONIUM ION, Ammonium transporter, CHLORIDE ION
Authors:Andrade, S.L, Pflueger, T, Gschell, M.
Deposit date:2023-09-12
Release date:2024-06-12
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:How sensor Amt-like proteins integrate ammonium signals.
Sci Adv, 10, 2024
8QPF
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BU of 8qpf by Molmil
Ammonium Transporter Amt1 from Shewanella denitrificans
Descriptor: Ammonium transporter
Authors:Gschell, M, Zhang, L, Einsle, O, Andrade, S.
Deposit date:2023-10-01
Release date:2024-06-12
Method:ELECTRON MICROSCOPY (2.53 Å)
Cite:How sensor Amt-like proteins integrate ammonium signals.
Sci Adv, 10, 2024
8QJ3
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BU of 8qj3 by Molmil
Receptor Sd-Amt1 (OFF-state)
Descriptor: Ammonium transporter, CHLORIDE ION, DODECYL-BETA-D-MALTOSIDE
Authors:Andrade, S.L, Pflueger, T, Gschell, M.
Deposit date:2023-09-12
Release date:2024-06-12
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:How sensor Amt-like proteins integrate ammonium signals.
Sci Adv, 10, 2024
1CIX
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BU of 1cix by Molmil
THREE-DIMENSIONAL STRUCTURE OF ANTIMICROBIAL PEPTIDE TACHYSTATIN A ISOLATED FROM HORSESHOE CRAB
Descriptor: PROTEIN (TACHYSTATIN A)
Authors:Fujitani, N, Kawabata, S, Osaki, T, Kumaki, Y, Demura, M, Nitta, K, Kawano, K.
Deposit date:1999-04-06
Release date:2002-05-01
Last modified:2024-10-30
Method:SOLUTION NMR
Cite:Structure of the antimicrobial peptide tachystatin A.
J.Biol.Chem., 277, 2002
1FQY
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BU of 1fqy by Molmil
STRUCTURE OF AQUAPORIN-1 AT 3.8 A RESOLUTION BY ELECTRON CRYSTALLOGRAPHY
Descriptor: AQUAPORIN-1
Authors:Murata, K, Mitsuoka, K, Hirai, T, Walz, T, Agre, P, Heymann, J.B, Engel, A, Fujiyoshi, Y.
Deposit date:2000-09-07
Release date:2000-10-18
Last modified:2024-04-17
Method:ELECTRON CRYSTALLOGRAPHY (3.8 Å)
Cite:Structural determinants of water permeation through aquaporin-1.
Nature, 407, 2000
7Y46
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BU of 7y46 by Molmil
Cryo-EM structure of the Na+,K+-ATPase in the E2.2K+ state after addition of ATP
Descriptor: 1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Kanai, R, Cornelius, F, Vilsen, B, Toyoshima, C.
Deposit date:2022-06-14
Release date:2022-07-13
Last modified:2024-10-30
Method:ELECTRON MICROSCOPY (7.2 Å)
Cite:Cryo-electron microscopy of Na + ,K + -ATPase reveals how the extracellular gate locks in the E2·2K + state.
Febs Lett., 596, 2022
4CSK
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BU of 4csk by Molmil
human Aquaporin
Descriptor: AQUAPORIN-1
Authors:Ruiz-Carrillo, D, To-Yiu-Ying, J, Darwis, D, Soon, C.H, Cornvik, T, Torres, J, Lescar, J.
Deposit date:2014-03-08
Release date:2014-12-24
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (3.28 Å)
Cite:Crystallization and Preliminary Crystallographic Analysis of Human Aquaporin 1 at a Resolution of 3.28 A.
Acta Crystallogr.,Sect.F, 70, 2014
7W3Y
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BU of 7w3y by Molmil
CryoEM structure of human Kv4.3
Descriptor: Isoform 2 of Potassium voltage-gated channel subfamily D member 3
Authors:Ma, D.M, Guo, J.T.
Deposit date:2021-11-26
Release date:2022-11-02
Last modified:2024-06-26
Method:ELECTRON MICROSCOPY (3 Å)
Cite:Structural basis for the gating modulation of Kv4.3 by auxiliary subunits.
Cell Res., 32, 2022
3HZQ
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BU of 3hzq by Molmil
Structure of a tetrameric MscL in an expanded intermediate state
Descriptor: Large-conductance mechanosensitive channel
Authors:Liu, Z.F, Gandhi, C.S, Rees, D.C.
Deposit date:2009-06-24
Release date:2009-08-25
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (3.82 Å)
Cite:Structure of a tetrameric MscL in an expanded intermediate state.
Nature, 461, 2009
1BKT
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BU of 1bkt by Molmil
BMKTX TOXIN FROM SCORPION BUTHUS MARTENSII KARSCH, NMR, 25 STRUCTURES
Descriptor: BMKTX
Authors:Renisio, J.G, Romi-Lebrun, R, Blanc, E, Bornet, O, Nakajima, T, Darbon, H.
Deposit date:1998-07-03
Release date:1999-01-13
Last modified:2024-10-23
Method:SOLUTION NMR
Cite:Solution structure of BmKTX, a K+ blocker toxin from the Chinese scorpion Buthus Martensi
Proteins, 38, 2000
7VVH
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BU of 7vvh by Molmil
Crystal Structure of the Kv7.1 C-terminal Domain in Complex with Calmodulin disease mutation E140G
Descriptor: CALCIUM ION, Calmodulin-1, Potassium voltage-gated channel subfamily KQT member 1,Potassium voltage-gated channel subfamily KQT member 1
Authors:Chen, L.
Deposit date:2021-11-06
Release date:2022-11-09
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.296 Å)
Cite:Crystal Structure of the Kv7.1 C-terminal Domain in Complex with Calmodulin disease mutation F141L
To Be Published
7VVD
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BU of 7vvd by Molmil
Crystal Structure of the Kv7.1 C-terminal Domain in Complex with Calmodulin disease mutation Q135P
Descriptor: CALCIUM ION, Calmodulin-1, Potassium voltage-gated channel subfamily KQT member 1,Potassium voltage-gated channel subfamily KQT member 1
Authors:Chen, L.
Deposit date:2021-11-05
Release date:2022-11-09
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (3.134 Å)
Cite:Crystal Structure of the Kv7.1 C-terminal Domain in Complex with Calmodulin disease mutation F141L
To Be Published
6S5C
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BU of 6s5c by Molmil
Square conformation of KtrA WT ring with bound ATP and calcium
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, CALCIUM ION, Ktr system potassium uptake protein A
Authors:Teixeira-Duarte, C.M, Fonseca, F, Morais-Cabral, J.H.
Deposit date:2019-07-01
Release date:2020-01-08
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (3 Å)
Cite:Activation of a nucleotide-dependent RCK domain requires binding of a cation cofactor to a conserved site.
Elife, 8, 2019
7Y45
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BU of 7y45 by Molmil
Cryo-EM structure of the Na+,K+-ATPase in the E2.2K+ state
Descriptor: 1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Kanai, R, Cornelius, F, Vilsen, B, Toyoshima, C.
Deposit date:2022-06-14
Release date:2022-07-13
Last modified:2024-10-30
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:Cryo-electron microscopy of Na + ,K + -ATPase reveals how the extracellular gate locks in the E2·2K + state.
Febs Lett., 596, 2022
1H6I
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BU of 1h6i by Molmil
A REFINED STRUCTURE OF HUMAN AQUAPORIN 1
Descriptor: AQUAPORIN-1
Authors:De Groot, B.L, Engel, A, Grubmuller, H.
Deposit date:2001-06-15
Release date:2001-12-13
Last modified:2024-05-01
Method:ELECTRON CRYSTALLOGRAPHY (3.54 Å)
Cite:A Refined Structure of Human Aquaporin 1
FEBS Lett., 504, 2001
6E7P
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BU of 6e7p by Molmil
cryo-EM structure of human TRPML1 with PI35P2
Descriptor: (1R,2S,3S,4R,5S,6R)-5-{[(R)-[(2R)-2,3-bis{[(1S)-1-hydroxyoctyl]oxy}propoxy](hydroxy)phosphoryl]oxy}-2,4,6-trihydroxycyclohexane-1,3-diyl bis[dihydrogen (phosphate)], Mucolipin-1
Authors:Schmiege, P, Li, X.
Deposit date:2018-07-27
Release date:2018-11-28
Last modified:2024-11-06
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:Structural basis for PtdInsP2-mediated human TRPML1 regulation.
Nat Commun, 9, 2018
6E7Y
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BU of 6e7y by Molmil
cryo-EM structure of human TRPML1 with PI45P2
Descriptor: Mucolipin-1, [(2R)-2-octanoyloxy-3-[oxidanyl-[(1R,2R,3S,4R,5R,6S)-2,3,6-tris(oxidanyl)-4,5-diphosphonooxy-cyclohexyl]oxy-phosphoryl]oxy-propyl] octanoate
Authors:Schmiege, P, Li, X.
Deposit date:2018-07-27
Release date:2018-11-28
Last modified:2024-10-30
Method:ELECTRON MICROSCOPY (3.57 Å)
Cite:Structural basis for PtdInsP2-mediated human TRPML1 regulation.
Nat Commun, 9, 2018
6E7Z
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BU of 6e7z by Molmil
cryo-EM structure of human TRPML1 with ML-SA1 and PI35P2
Descriptor: (1R,2S,3S,4R,5S,6R)-5-{[(R)-[(2R)-2,3-bis{[(1S)-1-hydroxyoctyl]oxy}propoxy](hydroxy)phosphoryl]oxy}-2,4,6-trihydroxycyclohexane-1,3-diyl bis[dihydrogen (phosphate)], 2-{2-oxo-2-[(4S)-2,2,4-trimethyl-3,4-dihydroquinolin-1(2H)-yl]ethyl}-1H-isoindole-1,3(2H)-dione, Mucolipin-1
Authors:Schmiege, P, Li, X.
Deposit date:2018-07-27
Release date:2018-11-28
Method:ELECTRON MICROSCOPY (3.73 Å)
Cite:Structural basis for PtdInsP2-mediated human TRPML1 regulation.
Nat Commun, 9, 2018
7MGL
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BU of 7mgl by Molmil
Structure of human TRPML1 with ML-SI3
Descriptor: 1,2-Distearoyl-sn-glycerophosphoethanolamine, Mucolipin-1, N-{(1S,2S)-2-[4-(2-methoxyphenyl)piperazin-1-yl]cyclohexyl}benzenesulfonamide
Authors:Schmiege, P, Li, X.
Deposit date:2021-04-12
Release date:2021-06-16
Last modified:2024-10-16
Method:ELECTRON MICROSCOPY (2.9 Å)
Cite:Atomic insights into ML-SI3 mediated human TRPML1 inhibition.
Structure, 29, 2021
6X35
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BU of 6x35 by Molmil
Pig R615C RyR1 in complex with CaM, EGTA (class 1, open)
Descriptor: Calmodulin-1, Peptidyl-prolyl cis-trans isomerase FKBP1B, Ryanodine Receptor, ...
Authors:Woll, K.W, Haji-Ghassemi, O, Van Petegem, F.
Deposit date:2020-05-21
Release date:2021-01-13
Last modified:2024-03-06
Method:ELECTRON MICROSCOPY (4.2 Å)
Cite:Pathological conformations of disease mutant Ryanodine Receptors revealed by cryo-EM.
Nat Commun, 12, 2021
6X33
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BU of 6x33 by Molmil
Wt pig RyR1 in complex with apoCaM, EGTA condition (class 3, open)
Descriptor: Calmodulin-1, Peptidyl-prolyl cis-trans isomerase FKBP1B, Ryanodine Receptor, ...
Authors:Woll, K.W, Haji-Ghassemi, O, Van Petegem, F.
Deposit date:2020-05-21
Release date:2021-01-13
Last modified:2024-11-06
Method:ELECTRON MICROSCOPY (4.2 Å)
Cite:Pathological conformations of disease mutant Ryanodine Receptors revealed by cryo-EM.
Nat Commun, 12, 2021
6Y94
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BU of 6y94 by Molmil
Ca2+-bound Calmodulin mutant N53I
Descriptor: CALCIUM ION, Calmodulin
Authors:Holt, C, Nielsen, L.H, Lau, K, Brohus, M, Sorensen, A.B, Larsen, K.T, Sommer, C, Petegem, F.V, Overgaard, M.T, Wimmer, R.
Deposit date:2020-03-06
Release date:2020-04-29
Last modified:2024-06-19
Method:SOLUTION NMR
Cite:The arrhythmogenic N53I variant subtly changes the structure and dynamics in the calmodulin N-terminal domain, altering its interaction with the cardiac ryanodine receptor.
J.Biol.Chem., 295, 2020
6X32
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BU of 6x32 by Molmil
Wt pig RyR1 in complex with apoCaM, EGTA condition (class 1 and 2, closed)
Descriptor: Calmodulin-1, Peptidyl-prolyl cis-trans isomerase FKBP1B, Ryanodine Receptor, ...
Authors:Woll, K.W, Haji-Ghassemi, O, Van Petegem, F.
Deposit date:2020-05-21
Release date:2021-01-13
Last modified:2024-03-06
Method:ELECTRON MICROSCOPY (3.8 Å)
Cite:Pathological conformations of disease mutant Ryanodine Receptors revealed by cryo-EM.
Nat Commun, 12, 2021
6Y95
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BU of 6y95 by Molmil
Ca2+-free Calmodulin mutant N53I
Descriptor: Calmodulin
Authors:Holt, C, Hamborg, L.N, Lau, K, Brohus, M, Sorensen, A.B, Larsen, K.T, Sommer, C, Petegem, F.V, Overgaard, M.T, Wimmer, R.
Deposit date:2020-03-06
Release date:2020-04-29
Last modified:2024-06-19
Method:SOLUTION NMR
Cite:The arrhythmogenic N53I variant subtly changes the structure and dynamics in the calmodulin N-terminal domain, altering its interaction with the cardiac ryanodine receptor.
J.Biol.Chem., 295, 2020

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