7MGL
Structure of human TRPML1 with ML-SI3
Summary for 7MGL
Entry DOI | 10.2210/pdb7mgl/pdb |
EMDB information | 23828 |
Descriptor | Mucolipin-1, N-{(1S,2S)-2-[4-(2-methoxyphenyl)piperazin-1-yl]cyclohexyl}benzenesulfonamide, 1,2-Distearoyl-sn-glycerophosphoethanolamine (3 entities in total) |
Functional Keywords | trpml, calcium, ml-si3, membrane protein |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 4 |
Total formula weight | 265050.55 |
Authors | Schmiege, P.,Li, X. (deposition date: 2021-04-12, release date: 2021-06-16, Last modification date: 2021-11-17) |
Primary citation | Schmiege, P.,Fine, M.,Li, X. Atomic insights into ML-SI3 mediated human TRPML1 inhibition. Structure, 29:1295-1302.e3, 2021 Cited by PubMed: 34171299DOI: 10.1016/j.str.2021.06.003 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (2.9 Å) |
Structure validation
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