1LV1
 
 | | Crystal Structure Analysis of the non-active site mutant of tethered HIV-1 protease to 2.1A resolution | | Descriptor: | HIV-1 protease | | Authors: | Kumar, M, Kannan, K.K, Hosur, M.V, Bhavesh, N.S, Chatterjee, A, Mittal, R, Hosur, R.V. | | Deposit date: | 2002-05-24 | | Release date: | 2002-06-19 | | Last modified: | 2024-05-29 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | Effects of remote mutation on the autolysis of HIV-1 PR: X-ray and NMR investigations.
Biochem.Biophys.Res.Commun., 294, 2002
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1H9X
 | | Cytochrome cd1 Nitrite Reductase, reduced form | | Descriptor: | 2-[N-CYCLOHEXYLAMINO]ETHANE SULFONIC ACID, CYTOCHROME CD1 NITRITE REDUCTASE, HEME C, ... | | Authors: | Sjogren, T, Hajdu, J. | | Deposit date: | 2001-03-23 | | Release date: | 2001-08-09 | | Last modified: | 2023-12-13 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | The Structure of an Alternative Form of Paracoccus Pantotrophus Cytochrome Cd1 Nitrite Reductase
J.Biol.Chem., 276, 2001
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5CRI
 | | Wild-type Bacillus subtilis lipase A with 0% [BMIM][Cl] | | Descriptor: | Esterase, SULFATE ION | | Authors: | Nordwald, E.M, Plaks, J.G, Snell, J.R, Sousa, M.C, Kaar, J.L. | | Deposit date: | 2015-07-22 | | Release date: | 2015-11-04 | | Last modified: | 2024-03-06 | | Method: | X-RAY DIFFRACTION (1.63 Å) | | Cite: | Crystallographic Investigation of Imidazolium Ionic Liquid Effects on Enzyme Structure.
Chembiochem, 16, 2015
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1ERR
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7L2H
 | | Cryo-EM structure of unliganded full-length TRPV1 at neutral pH | | Descriptor: | (10R,13S)-16-amino-13-hydroxy-7,13-dioxo-8,12,14-trioxa-13lambda~5~-phosphahexadecan-10-yl tridecanoate, (2S)-1-(butanoyloxy)-3-{[(R)-hydroxy{[(1r,2R,3S,4S,5R,6S)-2,3,4,5,6-pentahydroxycyclohexyl]oxy}phosphoryl]oxy}propan-2-yl tridecanoate, SODIUM ION, ... | | Authors: | Zhang, K, Julius, D, Cheng, Y. | | Deposit date: | 2020-12-17 | | Release date: | 2021-09-22 | | Last modified: | 2021-10-13 | | Method: | ELECTRON MICROSCOPY (2.63 Å) | | Cite: | Structural snapshots of TRPV1 reveal mechanism of polymodal functionality.
Cell, 184, 2021
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5T5U
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6WLO
 | | hc16 ligase models, 11.0 Angstrom resolution | | Descriptor: | RNA (338-MER) | | Authors: | Kappel, K, Zhang, K, Su, Z, Watkins, A.M, Kladwang, W, Li, S, Pintilie, G, Topkar, V.V, Rangan, R, Zheludev, I.N, Yesselman, J.D, Chiu, W, Das, R. | | Deposit date: | 2020-04-20 | | Release date: | 2020-07-08 | | Last modified: | 2024-03-06 | | Method: | ELECTRON MICROSCOPY (11 Å) | | Cite: | Accelerated cryo-EM-guided determination of three-dimensional RNA-only structures.
Nat.Methods, 17, 2020
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8HIH
 | | Cryo-EM structure of Mycobacterium tuberculosis transcription initiation complex with transcription factor GlnR | | Descriptor: | DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ... | | Authors: | Lin, W, Shi, J, Xu, J.C. | | Deposit date: | 2022-11-20 | | Release date: | 2023-06-07 | | Last modified: | 2024-07-31 | | Method: | ELECTRON MICROSCOPY (3.66 Å) | | Cite: | Structural insights into the transcription activation mechanism of the global regulator GlnR from actinobacteria.
Proc.Natl.Acad.Sci.USA, 120, 2023
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1HC1
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5ODD
 | | HUMAN MED26 N-TERMINAL DOMAIN (1-92) | | Descriptor: | Mediator of RNA polymerase II transcription subunit 26 | | Authors: | Lens, Z, Cantrelle, F.-X, Perruzini, R, Dewitte, F, Hanoulle, X, Villeret, V, Verger, A, Landrieu, I. | | Deposit date: | 2017-07-05 | | Release date: | 2017-11-29 | | Last modified: | 2024-06-19 | | Method: | SOLUTION NMR | | Cite: | 1H, 15N and 13C assignments of the N-terminal domain of the Mediator complex subunit MED26.
Biomol.Nmr Assign., 10, 2016
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3G1Q
 | | Crystal structure of sterol 14-alpha demethylase (CYP51) from Trypanosoma brucei in ligand free state | | Descriptor: | PROTOPORPHYRIN IX CONTAINING FE, Sterol 14-alpha-demethylase | | Authors: | Lepesheva, G.I, Hargrove, T.Y, Harp, J, Wawrzak, Z, Waterman, M.R, Park, H. | | Deposit date: | 2009-01-30 | | Release date: | 2009-10-06 | | Last modified: | 2023-09-06 | | Method: | X-RAY DIFFRACTION (1.89 Å) | | Cite: | Crystal structures of Trypanosoma brucei sterol 14alpha-demethylase and implications for selective treatment of human infections.
J.Biol.Chem., 285, 2010
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2Y1M
 | | Structure of native c-Cbl | | Descriptor: | CALCIUM ION, E3 UBIQUITIN-PROTEIN LIGASE, ZINC ION | | Authors: | Dou, H, Sibbet, G.J, Huang, D.T. | | Deposit date: | 2010-12-08 | | Release date: | 2012-01-18 | | Last modified: | 2023-12-20 | | Method: | X-RAY DIFFRACTION (2.67 Å) | | Cite: | Structural Basis for Autoinhibition and Phosphorylation-Dependent Activation of C-Cbl.
Nat.Struct.Mol.Biol., 19, 2012
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2CW9
 | | Crystal structure of human Tim44 C-terminal domain | | Descriptor: | PENTAETHYLENE GLYCOL, translocase of inner mitochondrial membrane | | Authors: | Handa, N, Kishishita, S, Morita, S, Kinoshita, Y, Nagano, Y, Uda, H, Terada, T, Uchikubo, T, Takemoto, C, Jin, Z, Chrzas, J, Chen, L, Liu, Z.-J, Wang, B.-C, Shirouzu, M, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | | Deposit date: | 2005-06-17 | | Release date: | 2005-12-17 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | Structure of the human Tim44 C-terminal domain in complex with pentaethylene glycol: ligand-bound form.
Acta Crystallogr.,Sect.D, 63, 2007
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4M00
 | | Crystal structure of the ligand binding region of staphylococcal adhesion SraP | | Descriptor: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CALCIUM ION, Serine-rich adhesin for platelets, ... | | Authors: | Yang, Y.H, Jiang, Y.L, Zhang, J, Wang, L, Chen, Y, Zhou, C.Z. | | Deposit date: | 2013-08-01 | | Release date: | 2014-06-18 | | Last modified: | 2023-11-08 | | Method: | X-RAY DIFFRACTION (2.05 Å) | | Cite: | Structural Insights into SraP-Mediated Staphylococcus aureus Adhesion to Host Cells
Plos Pathog., 10, 2014
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7OPD
 | | Pol II-CSB-CRL4CSA-UVSSA-SPT6-PAF (Structure 5) | | Descriptor: | Cullin-4A, DNA damage-binding protein 1, DNA excision repair protein ERCC-6, ... | | Authors: | Kokic, G, Cramer, P. | | Deposit date: | 2021-05-31 | | Release date: | 2021-10-06 | | Last modified: | 2024-07-17 | | Method: | ELECTRON MICROSCOPY (3 Å) | | Cite: | Structural basis of human transcription-DNA repair coupling.
Nature, 598, 2021
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7OPC
 | | Pol II-CSB-CRL4CSA-UVSSA-SPT6-PAF (Structure 4) | | Descriptor: | Cullin-4A, DNA damage-binding protein 1, DNA excision repair protein ERCC-6, ... | | Authors: | Kokic, G, Cramer, P. | | Deposit date: | 2021-05-31 | | Release date: | 2021-10-13 | | Last modified: | 2024-07-17 | | Method: | ELECTRON MICROSCOPY (3 Å) | | Cite: | Structural basis of human transcription-DNA repair coupling.
Nature, 598, 2021
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6HX8
 | | Tubulin-STX3451 complex | | Descriptor: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CALCIUM ION, GUANOSINE-5'-DIPHOSPHATE, ... | | Authors: | Dohle, W, Prota, A.E, Menchon, G, Hamel, E, Steinmetz, M.O, Potter, B.V.L. | | Deposit date: | 2018-10-16 | | Release date: | 2019-02-27 | | Last modified: | 2024-01-24 | | Method: | X-RAY DIFFRACTION (2.402 Å) | | Cite: | Tetrahydroisoquinoline Sulfamates as Potent Microtubule Disruptors: Synthesis, Antiproliferative and Antitubulin Activity of Dichlorobenzyl-Based Derivatives, and a Tubulin Cocrystal Structure.
ACS Omega, 4, 2019
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1RRV
 | | X-ray crystal structure of TDP-vancosaminyltransferase GtfD as a complex with TDP and the natural substrate, desvancosaminyl vancomycin. | | Descriptor: | DESVANCOSAMINYL VANCOMYCIN, GLYCEROL, GLYCOSYLTRANSFERASE GTFD, ... | | Authors: | Mulichak, A.M, Lu, W, Losey, H.C, Walsh, C.T, Garavito, R.M. | | Deposit date: | 2003-12-09 | | Release date: | 2004-05-18 | | Last modified: | 2023-11-15 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Crystal Structure of Vancosaminyltransferase Gtfd from the Vancomycin Biosynthetic Pathway: Interactions with Acceptor and Nucleotide Ligands
Biochemistry, 43, 2004
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5B4Y
 | | Crystal structure of the LA12 fragment of ApoER2 | | Descriptor: | CALCIUM ION, Low-density lipoprotein receptor-related protein 8 | | Authors: | Nogi, T, Tabata, S, Hirai, H, Yasui, N, Takagi, J. | | Deposit date: | 2016-04-20 | | Release date: | 2017-04-26 | | Last modified: | 2023-11-08 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | Crystal structure of the ectodomain from a LDLR close homologue in complex with its physiological ligand.
To Be Published
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4JYJ
 | | Crystal Structure of putative enoyl-CoA hydratase/isomerase from Novosphingobium aromaticivorans DSM 12444 | | Descriptor: | Enoyl-CoA hydratase/isomerase, UNKNOWN LIGAND | | Authors: | Cooper, D.R, Porebski, P.J, Domagalski, M.J, Ahmed, M, Stead, M, Hillerich, B, Seidel, R, Zimmerman, M, Bonanno, J.B, Almo, S.C, Minor, W, New York Structural Genomics Research Consortium (NYSGRC) | | Deposit date: | 2013-03-29 | | Release date: | 2013-05-29 | | Last modified: | 2022-04-13 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | Crystal Structure of putative enoyl-CoA hydratase/isomerase from Novosphingobium aromaticivorans DSM 12444
To be Published
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1ERE
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2Q7J
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2QDR
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6KNZ
 | | Crystal structure of T2R-TTL-KXO1 complex | | Descriptor: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 2-[5-[4-(2-morpholin-4-ylethoxy)phenyl]pyridin-2-yl]-~{N}-(phenylmethyl)ethanamide, CALCIUM ION, ... | | Authors: | Chen, Q, Yu, Y. | | Deposit date: | 2019-08-07 | | Release date: | 2019-10-23 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (2.475 Å) | | Cite: | Reversible binding of the anticancer drug KXO1 (tirbanibulin) to the colchicine-binding site of beta-tubulin explains KXO1's low clinical toxicity.
J.Biol.Chem., 294, 2019
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1KCD
 | | Endopolygalacturonase I from Stereum purpureum complexed with two galacturonate at 1.15 A resolution. | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, ENDOPOLYGALACTURONASE, ... | | Authors: | Shimizu, T, Nakatsu, T, Miyairi, K, Okuno, T, Kato, H. | | Deposit date: | 2001-11-08 | | Release date: | 2002-06-05 | | Last modified: | 2023-11-15 | | Method: | X-RAY DIFFRACTION (1.15 Å) | | Cite: | Active-site architecture of endopolygalacturonase I from Stereum purpureum revealed by crystal structures in native and ligand-bound forms at atomic resolution.
Biochemistry, 41, 2002
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