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4GXR
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BU of 4gxr by Molmil
Structure of ATP bound RpMatB-BxBclM chimera B3
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, CARBONATE ION, GLYCEROL, ...
Authors:Rank, K.C, Crosby, H.A, Escalante-Semerena, J.C, Rayment, I.
Deposit date:2012-09-04
Release date:2012-10-24
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural Insights into the Substrate Specificity of the Rhodopseudomonas palustris Protein Acetyltransferase RpPat: IDENTIFICATION OF A LOOP CRITICAL FOR RECOGNITION BY RpPat.
J.Biol.Chem., 287, 2012
4FUT
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BU of 4fut by Molmil
Crystal structure of ATP bound MatB from Rhodopseudomonas palustris
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, GLYCEROL, MAGNESIUM ION, ...
Authors:Rank, K.C, Crosby, H.A, Escalante-Semerena, J.C, Rayment, I.
Deposit date:2012-06-28
Release date:2012-07-25
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structure-Guided Expansion of the Substrate Range of Methylmalonyl Coenzyme A Synthetase (MatB) of Rhodopseudomonas palustris.
Appl.Environ.Microbiol., 78, 2012
6DI8
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BU of 6di8 by Molmil
Crystal structure of bovine alpha-chymotrypsin in space group P65
Descriptor: Chymotrypsin A chain A, Chymotrypsin A chain B, Chymotrypsin A chain C, ...
Authors:Marshall, A.C, Keiller, B.G, Bruning, J.B.
Deposit date:2018-05-23
Release date:2019-01-23
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (1.859 Å)
Cite:Crystal Structure of Bovine Alpha-Chymotrypsin in Space Group P65
Crystals, 8, 2018
1EX3
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BU of 1ex3 by Molmil
CRYSTAL STRUCTURE OF BOVINE CHYMOTRYPSINOGEN A (TETRAGONAL)
Descriptor: CHYMOTRYPSINOGEN A
Authors:Pjura, P.E, Lenhoff, A.M, Leonard, S.A, Gittis, A.G.
Deposit date:2000-04-28
Release date:2000-05-17
Last modified:2017-10-04
Method:X-RAY DIFFRACTION (3 Å)
Cite:Protein crystallization by design: chymotrypsinogen without precipitants.
J.Mol.Biol., 300, 2000
2AHI
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BU of 2ahi by Molmil
Structural Basis of DNA Recognition by p53 Tetramers (complex III)
Descriptor: 5'-D(*CP*GP*GP*AP*CP*AP*TP*GP*TP*CP*CP*G)-3', Cellular tumor antigen p53, ZINC ION
Authors:Kitayner, M, Rozenberg, H, Kessler, N, Rabinovich, D, Shakked, Z.
Deposit date:2005-07-28
Release date:2006-07-11
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Structural Basis of DNA Recognition by p53 Tetramers
Mol.Cell, 22, 2006
5LGY
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BU of 5lgy by Molmil
Lysine 120-acetylated P53 DNA binding domain in a complex with the BAX response element.
Descriptor: Cellular tumor antigen p53, DNA (5'-D(*AP*GP*GP*CP*TP*TP*GP*TP*CP*TP*CP*TP*AP*AP*CP*TP*TP*GP*TP*GP*A)-3'), DNA (5'-D(*TP*CP*AP*CP*AP*AP*GP*TP*TP*AP*GP*AP*GP*AP*CP*AP*AP*GP*CP*CP*T)-3'), ...
Authors:Arbely, E, Vainer, R.
Deposit date:2016-07-08
Release date:2016-07-27
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.92 Å)
Cite:Structural Basis for p53 Lys120-Acetylation-Dependent DNA-Binding Mode.
J.Mol.Biol., 428, 2016
5XZC
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BU of 5xzc by Molmil
Cryo-EM structure of p300-p53 protein complex
Descriptor: Cellular tumor antigen p53, Histone acetyltransferase p300
Authors:Ghosh, R, Roy, S, Sengupta, J.
Deposit date:2017-07-12
Release date:2019-01-23
Last modified:2024-03-27
Method:ELECTRON MICROSCOPY (10.7 Å)
Cite:Tumor suppressor p53-mediated structural reorganization of the transcriptional coactivator p300.
Biochemistry, 2019
3Q01
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BU of 3q01 by Molmil
An induced fit mechanism regulates p53 DNA binding kinetics to confer sequence specificity
Descriptor: Cellular tumor antigen p53, ZINC ION
Authors:Petty, T.J, Halazonetis, T.D.
Deposit date:2010-12-15
Release date:2011-05-11
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:An induced fit mechanism regulates p53 DNA binding kinetics to confer sequence specificity.
Embo J., 30, 2011
1R7M
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BU of 1r7m by Molmil
The homing endonuclease I-SceI bound to its DNA recognition region
Descriptor: 5'-D(*CP*AP*CP*GP*CP*TP*AP*GP*GP*GP*AP*TP*AP*AP*CP*AP*GP*GP*GP*TP*AP*AP*TP*AP*C)-3', 5'-D(*GP*GP*TP*AP*TP*TP*AP*CP*CP*CP*TP*GP*TP*TP*AP*TP*CP*CP*CP*TP*AP*GP*CP*GP*T)-3', CALCIUM ION, ...
Authors:Moure, C.M, Gimble, F.S, Quiocho, F.A.
Deposit date:2003-10-21
Release date:2004-10-26
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:The crystal structure of the gene targeting homing endonuclease I-SceI reveals the origins of its target site specificity
J.Mol.Biol., 334, 2003
2YBG
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BU of 2ybg by Molmil
Structure of Lys120-acetylated p53 core domain
Descriptor: CELLULAR TUMOR ANTIGEN P53, ZINC ION
Authors:Arbely, E, Allen, M.D, Joerger, A.C, Fersht, A.R.
Deposit date:2011-03-08
Release date:2011-05-04
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Acetylation of Lysine 120 of P53 Endows DNA- Binding Specificity at Effective Physiological Salt Concentration.
Proc.Natl.Acad.Sci.USA, 108, 2011
1RTU
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BU of 1rtu by Molmil
USTILAGO SPHAEROGENA RIBONUCLEASE U2
Descriptor: RIBONUCLEASE U2, SULFATE ION
Authors:Noguchi, S, Satow, Y, Uchida, T, Sasaki, C, Matsuzaki, T.
Deposit date:1995-05-12
Release date:1996-11-08
Last modified:2023-08-09
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Crystal structure of Ustilago sphaerogena ribonuclease U2 at 1.8 A resolution.
Biochemistry, 34, 1995
6UE7
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BU of 6ue7 by Molmil
Structure of dimeric sIgA complex
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Immunoglobulin J chain, ...
Authors:Kumar, N, Arthur, C.P, Ciferri, C, Matsumoto, M.L.
Deposit date:2019-09-20
Release date:2020-02-19
Last modified:2020-07-29
Method:ELECTRON MICROSCOPY (2.9 Å)
Cite:Structure of the secretory immunoglobulin A core.
Science, 367, 2020
2MEJ
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BU of 2mej by Molmil
Solution Structure of the Complex Between BCL-xL and the p53 Core Domain determined with PRE restraints
Descriptor: Bcl-2-like protein 1, Cellular tumor antigen p53, ZINC ION
Authors:Viacava Follis, A, Grace, C.R, Kriwacki, R.W.
Deposit date:2013-09-25
Release date:2014-04-30
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:The DNA-binding domain mediates both nuclear and cytosolic functions of p53.
Nat.Struct.Mol.Biol., 21, 2014
4VGC
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BU of 4vgc by Molmil
GAMMA-CHYMOTRYPSIN D-NAPHTHYL-1-ACETAMIDO BORONIC ACID INHIBITOR COMPLEX
Descriptor: D-1-NAPHTHYL-2-ACETAMIDO-ETHANE BORONIC ACID, GAMMA CHYMOTRYPSIN, SULFATE ION
Authors:Stoll, V.S, Eger, B.T, Hynes, R.C, Martichonok, V, Jones, J.B, Pai, E.F.
Deposit date:1997-05-01
Release date:1997-11-12
Last modified:2023-08-09
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Differences in binding modes of enantiomers of 1-acetamido boronic acid based protease inhibitors: crystal structures of gamma-chymotrypsin and subtilisin Carlsberg complexes.
Biochemistry, 37, 1998
4Q2K
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BU of 4q2k by Molmil
Bovine alpha chymotrypsin bound to a cyclic peptide inhibitor, 5b
Descriptor: (11S)-4,9-dioxo-N-[(2S)-1-oxo-3-phenylpropan-2-yl]-17,22-dioxa-10,30-diazatetracyclo[21.2.2.2~13,16~.1~5,8~]triaconta-1(25),5,7,13,15,23,26,28-octaene-11-carboxamide, Chymotrypsinogen A
Authors:Chan, H.Y, Bruning, J.B, Abell, A.D.
Deposit date:2014-04-09
Release date:2014-07-23
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Macrocyclic protease inhibitors with reduced peptide character.
Angew.Chem.Int.Ed.Engl., 53, 2014
4QO1
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BU of 4qo1 by Molmil
p53 DNA binding domain in complex with Nb139
Descriptor: Cellular tumor antigen p53, Nb139 Nanobody against the DNA-binding domain of p53, ZINC ION
Authors:De Gieter, S, Bethuyne, J, Gettemans, J, Garcia-Pino, A, Loris, R.
Deposit date:2014-06-19
Release date:2014-10-29
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.924 Å)
Cite:A nanobody modulates the p53 transcriptional program without perturbing its functional architecture.
Nucleic Acids Res., 42, 2014
8SKU
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BU of 8sku by Molmil
Structure of human SIgA1 in complex with human CD89 (FcaR1)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Immunoglobulin J chain, ...
Authors:Liu, Q, Stadtmueller, B.M.
Deposit date:2023-04-20
Release date:2023-10-25
Last modified:2023-11-08
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:SIgA structures bound to Streptococcus pyogenes M4 and human CD89 provide insights into host-pathogen interactions.
Nat Commun, 14, 2023
8SKV
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BU of 8skv by Molmil
Structure of human SIgA1 in complex with Streptococcus pyogenes protein M4 (Arp4)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, IgA receptor, ...
Authors:Liu, Q, Stadtmueller, B.M.
Deposit date:2023-04-20
Release date:2023-10-25
Last modified:2023-11-08
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:SIgA structures bound to Streptococcus pyogenes M4 and human CD89 provide insights into host-pathogen interactions.
Nat Commun, 14, 2023
3VGC
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BU of 3vgc by Molmil
GAMMA-CHYMOTRYPSIN L-NAPHTHYL-1-ACETAMIDO BORONIC ACID ACID INHIBITOR COMPLEX
Descriptor: GAMMA CHYMOTRYPSIN, L-1-NAPHTHYL-2-ACETAMIDO-ETHANE BORONIC ACID, SULFATE ION
Authors:Stoll, V.S, Eger, B.T, Hynes, R.C, Martichonok, V, Jones, J.B, Pai, E.F.
Deposit date:1997-05-01
Release date:1997-11-12
Last modified:2023-08-09
Method:X-RAY DIFFRACTION (1.67 Å)
Cite:Differences in binding modes of enantiomers of 1-acetamido boronic acid based protease inhibitors: crystal structures of gamma-chymotrypsin and subtilisin Carlsberg complexes.
Biochemistry, 37, 1998
5J4S
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BU of 5j4s by Molmil
alpha-chymotrypsin from bovine pancreas in complex with a modified Bowman-Birk inhibitor from soybean
Descriptor: Bowman-Birk type proteinase inhibitor, Chymotrypsinogen A
Authors:Johansson, E, Tornoee, C.W.
Deposit date:2016-04-01
Release date:2017-04-12
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.103 Å)
Cite:Divergent Protein Synthesis of Bowman-Birk Protease Inhibitors, their Hydrodynamic Behavior and Co-crystallization with alpha-Chymotrypsin
Synlett, 2017
6FF9
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BU of 6ff9 by Molmil
Mutant R280K of human P53
Descriptor: Cellular tumor antigen p53, ZINC ION
Authors:Trovao, F.G, Gomes, A.S, Pinheiro, B, Carvalho, A.L, Romao, M.J.
Deposit date:2018-01-04
Release date:2018-04-25
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2 Å)
Cite:The Crystal Structure of the R280K Mutant of Human p53 Explains the Loss of DNA Binding.
Int J Mol Sci, 19, 2018
6FJ5
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BU of 6fj5 by Molmil
New Insights into the Role of DNA Shape on Its Recognition by p53 Proteins (complex p53DBD-AGG-HG)
Descriptor: 1,2-ETHANEDIOL, Cellular tumor antigen p53, DNA, ...
Authors:Golovenko, D, Rozenberg, H, Shakked, Z.
Deposit date:2018-01-20
Release date:2018-06-27
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.051 Å)
Cite:New Insights into the Role of DNA Shape on Its Recognition by p53 Proteins.
Structure, 26, 2018
6GCH
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BU of 6gch by Molmil
STRUCTURE OF CHYMOTRYPSIN-*TRIFLUOROMETHYL KETONE INHIBITOR COMPLEXES. COMPARISON OF SLOWLY AND RAPIDLY EQUILIBRATING INHIBITORS
Descriptor: 1,1,1-TRIFLUORO-3-ACETAMIDO-4-PHENYL BUTAN-2-ONE(N-ACETYL-L-PHENYLALANYL TRIFLUOROMETHYL KETONE), GAMMA-CHYMOTRYPSIN A
Authors:Brady, K, Wei, A, Ringe, D, Abeles, R.H.
Deposit date:1990-04-06
Release date:1990-10-15
Last modified:2024-06-05
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structure of chymotrypsin-trifluoromethyl ketone inhibitor complexes: comparison of slowly and rapidly equilibrating inhibitors.
Biochemistry, 29, 1990
5J4Q
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BU of 5j4q by Molmil
alpha-chymotrypsin from bovine pancreas in complex with Bowman-Birk inhibitor from soybean
Descriptor: Bowman-Birk type proteinase inhibitor, Chymotrypsinogen A
Authors:Johansson, E, Tornoee, C.W.
Deposit date:2016-04-01
Release date:2017-04-12
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.303 Å)
Cite:Divergent Protein Synthesis of Bowman-Birk Protease Inhibitors, their Hydrodynamic Behavior and Co-crystallization with alpha-Chymotrypsin
Synlett, 2017
8XP5
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BU of 8xp5 by Molmil
The Crystal Structure of p53/BCL-xL fusion complex from Biortus.
Descriptor: Bcl-2-like protein 1,Cellular tumor antigen p53, ZINC ION
Authors:Wang, F, Cheng, W, Yuan, Z, Lin, D, Bao, C.
Deposit date:2024-01-03
Release date:2024-03-06
Method:X-RAY DIFFRACTION (2.55 Å)
Cite:The Crystal Structure of p53/BCL-xL fusion complex from Biortus.
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