4VGC

GAMMA-CHYMOTRYPSIN D-NAPHTHYL-1-ACETAMIDO BORONIC ACID INHIBITOR COMPLEX

Summary for 4VGC

DescriptorGAMMA CHYMOTRYPSIN, SULFATE ION, D-1-NAPHTHYL-2-ACETAMIDO-ETHANE BORONIC ACID, ... (6 entities in total)
Functional Keywordshydrolase, serine protease
Biological sourceBos taurus (cattle)
Cellular locationSecreted, extracellular space P00766 P00766 P00766
Total number of polymer chains3
Total molecular weight25728.79
Authors
Stoll, V.S.,Eger, B.T.,Hynes, R.C.,Martichonok, V.,Jones, J.B.,Pai, E.F. (deposition date: 1997-05-01, release date: 1997-11-12, Last modification date: 2011-07-13)
Primary citation
Stoll, V.S.,Eger, B.T.,Hynes, R.C.,Martichonok, V.,Jones, J.B.,Pai, E.F.
Differences in binding modes of enantiomers of 1-acetamido boronic acid based protease inhibitors: crystal structures of gamma-chymotrypsin and subtilisin Carlsberg complexes.
Biochemistry, 37:451-462, 1998
PubMed: 9425066 (PDB entries with the same primary citation)
DOI: 10.1021/bi971166o
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (2.1 Å)
NMR Information
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Structure validation

ClashscoreRamachandran outliersSidechain outliers505.2%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
Download full validation report