6FML
 
 | | CryoEM Structure INO80core Nucleosome complex | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, Actin related protein 5, ... | | Authors: | Eustermann, S, Schall, K, Kostrewa, D, Strauss, M, Hopfner, K. | | Deposit date: | 2018-01-31 | | Release date: | 2018-04-25 | | Last modified: | 2024-05-15 | | Method: | ELECTRON MICROSCOPY (4.34 Å) | | Cite: | Structural basis for ATP-dependent chromatin remodelling by the INO80 complex.
Nature, 556, 2018
|
|
4OKL
 | |
6X59
 | | The mouse cGAS catalytic domain binding to human assembled nucleosome | | Descriptor: | Cyclic GMP-AMP synthase, DNA, Histone H2A type 1, ... | | Authors: | Pengbiao, X, Pingwei, L, Baoyu, Z. | | Deposit date: | 2020-05-25 | | Release date: | 2020-09-16 | | Last modified: | 2024-05-15 | | Method: | ELECTRON MICROSCOPY (2.98 Å) | | Cite: | The molecular basis of tight nuclear tethering and inactivation of cGAS.
Nature, 587, 2020
|
|
4OB4
 | | Structure of the S. venezulae BldD DNA-binding domain | | Descriptor: | Putative DNA-binding protein | | Authors: | schumacher, M.A, Tschowri, N, Buttner, M, Brennan, R. | | Deposit date: | 2014-01-06 | | Release date: | 2014-11-19 | | Last modified: | 2023-09-20 | | Method: | X-RAY DIFFRACTION (2.8 Å) | | Cite: | Tetrameric c-di-GMP mediates effective transcription factor dimerization to control Streptomyces development.
Cell(Cambridge,Mass.), 158, 2014
|
|
3AV2
 | | The human nucleosome structure containing the histone variant H3.3 | | Descriptor: | 146-MER DNA, Histone H2A type 1-B/E, Histone H2B type 1-J, ... | | Authors: | Tachiwana, H, Osakabe, A, Shiga, T, Miya, M, Kimura, H, Kagawa, W, Kurumizaka, H. | | Deposit date: | 2011-02-18 | | Release date: | 2011-06-01 | | Last modified: | 2023-11-01 | | Method: | X-RAY DIFFRACTION (2.8 Å) | | Cite: | Structures of human nucleosomes containing major histone H3 variants
Acta Crystallogr.,Sect.D, 67, 2011
|
|
8IIQ
 | | MsmUdgX H109S/E52N double mutant | | Descriptor: | IRON/SULFUR CLUSTER, Type-4 uracil-DNA glycosylase | | Authors: | Aroli, S. | | Deposit date: | 2023-02-24 | | Release date: | 2023-06-21 | | Last modified: | 2024-05-29 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | Mutational and structural analyses of UdgX: insights into the active site pocket architecture and its evolution.
Nucleic Acids Res., 51, 2023
|
|
8IIS
 | | MsmUdgX H109S/R184A double mutant | | Descriptor: | IRON/SULFUR CLUSTER, Type-4 uracil-DNA glycosylase | | Authors: | Aroli, S. | | Deposit date: | 2023-02-24 | | Release date: | 2023-06-21 | | Last modified: | 2024-05-29 | | Method: | X-RAY DIFFRACTION (1.61 Å) | | Cite: | Mutational and structural analyses of UdgX: insights into the active site pocket architecture and its evolution.
Nucleic Acids Res., 51, 2023
|
|
5A20
 | | Structure of bacteriophage SPP1 head-to-tail interface filled with DNA and tape measure protein | | Descriptor: | 15 PROTEIN, HEAD COMPLETION PROTEIN GP16, MAJOR TAIL PROTEIN GP17.1, ... | | Authors: | Chaban, Y, Lurz, R, Brasiles, S, Cornilleau, C, Karreman, M, Zinn-Justin, S, Tavares, P, Orlova, E.V. | | Deposit date: | 2015-05-06 | | Release date: | 2015-06-03 | | Last modified: | 2024-05-08 | | Method: | ELECTRON MICROSCOPY (7.6 Å) | | Cite: | Structural Rearrangements in the Phage Head-to-Tail Interface During Assembly and Infection.
Proc.Natl.Acad.Sci.USA, 112, 2015
|
|
8JNR
 | |
331D
 | | CRYSTAL STRUCTURE OF D(GCGCGCG) WITH 5'-OVERHANG G'S | | Descriptor: | COBALT HEXAMMINE(III), DNA (5'-D(*GP*CP*GP*CP*GP*CP*G)-3') | | Authors: | Pan, B, Ban, C, Wahl, M, Sundaralingam, M. | | Deposit date: | 1997-05-13 | | Release date: | 1997-09-24 | | Last modified: | 2024-04-03 | | Method: | X-RAY DIFFRACTION (1.65 Å) | | Cite: | Crystal structure of d(GCGCGCG) with 5'-overhang G residues.
Biophys.J., 73, 1997
|
|
3PNC
 | | Ternary crystal structure of a polymerase lambda variant with a GT mispair at the primer terminus and sodium at catalytic metal site | | Descriptor: | 2'-deoxy-5'-O-[(R)-hydroxy{[(S)-hydroxy(phosphonooxy)phosphoryl]methyl}phosphoryl]guanosine, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 5'-D(*CP*AP*GP*TP*AP*G)-3', ... | | Authors: | Bebenek, K, Pedersen, L.C, Kunkel, T.A. | | Deposit date: | 2010-11-18 | | Release date: | 2011-02-02 | | Last modified: | 2024-02-21 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Replication infidelity via a mismatch with Watson-Crick geometry.
Proc.Natl.Acad.Sci.USA, 108, 2011
|
|
8HNV
 | | CryoEM structure of HpaCas9-sgRNA-dsDNA in the presence of AcrIIC4 | | Descriptor: | CRISPR-associated endonuclease Cas9, anti-CRISPR protein AcrIIC4, non-target strand, ... | | Authors: | Sun, W, Cheng, Z, Wang, J, Yang, X, Wang, Y. | | Deposit date: | 2022-12-08 | | Release date: | 2023-07-19 | | Last modified: | 2024-07-03 | | Method: | ELECTRON MICROSCOPY (3.1 Å) | | Cite: | AcrIIC4 inhibits type II-C Cas9 by preventing R-loop formation.
Proc.Natl.Acad.Sci.USA, 120, 2023
|
|
3V62
 | | Structure of the S. cerevisiae Srs2 C-terminal domain in complex with PCNA conjugated to SUMO on lysine 164 | | Descriptor: | ATP-dependent DNA helicase SRS2, N-ETHYLMALEIMIDE, Proliferating cell nuclear antigen, ... | | Authors: | Armstrong, A.A, Mohideen, F, Lima, C.D. | | Deposit date: | 2011-12-18 | | Release date: | 2012-02-29 | | Last modified: | 2023-09-13 | | Method: | X-RAY DIFFRACTION (2.9 Å) | | Cite: | Recognition of SUMO-modified PCNA requires tandem receptor motifs in Srs2.
Nature, 483, 2012
|
|
5FXT
 | |
4PLB
 | | Crystal Structure of S.A. gyrase-AM8191 complex | | Descriptor: | 6-[({(1r,4S)-1-[(1S)-2-(3-fluoro-6-methoxy-1,5-naphthyridin-4-yl)-1-hydroxyethyl]-2-oxabicyclo[2.2.2]oct-4-yl}amino)methyl]-2H-pyrido[3,2-b][1,4]oxazin-3(4H)-one, Chimera protein of DNA gyrase subunits B and A, DNA (5'-D(P*AP*GP*CP*CP*GP*TP*AP*GP*GP*GP*CP*CP*CP*TP*AP*CP*GP*GP*CP*T)-3'), ... | | Authors: | Lu, J, Patel, S, Soisson, S. | | Deposit date: | 2014-05-16 | | Release date: | 2014-06-18 | | Last modified: | 2023-12-27 | | Method: | X-RAY DIFFRACTION (2.69 Å) | | Cite: | Oxabicyclooctane-linked novel bacterial topoisomerase inhibitors as broad spectrum antibacterial agents.
Acs Med.Chem.Lett., 5, 2014
|
|
5FVE
 | |
1Q2Z
 | | The 3D solution structure of the C-terminal region of Ku86 | | Descriptor: | ATP-dependent DNA helicase II, 80 kDa subunit | | Authors: | Harris, R, Esposito, D, Sankar, A, Maman, J.D, Hinks, J.A, Pearl, L.H, Driscoll, P.C. | | Deposit date: | 2003-07-28 | | Release date: | 2004-01-13 | | Last modified: | 2024-05-22 | | Method: | SOLUTION NMR | | Cite: | The 3D Solution Structure of the C-terminal Region of Ku86 (Ku86CTR)
J.Mol.Biol., 335, 2004
|
|
6A2H
 | | Architectural roles of Cren7 in folding crenarchaeal chromatin filament | | Descriptor: | Chromatin protein Cren7, DNA (5'-D(P*AP*AP*TP*TP*AP*C)-3'), DNA (5'-D(P*GP*TP*AP*AP*TP*T)-3') | | Authors: | Zhang, Z.F, Zhao, M.H, Chen, Y.Y, Wang, L, Dong, Y.H, Gong, Y, Huang, L. | | Deposit date: | 2018-06-11 | | Release date: | 2019-01-16 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | Architectural roles of Cren7 in folding crenarchaeal chromatin filament.
Mol. Microbiol., 111, 2019
|
|
2H05
 | |
4KYW
 | | Restriction endonuclease DPNI in complex with two DNA molecules | | Descriptor: | 5'-(*DC*DTP*DGP*DGP*6MAP*DTP*DCP*DCP*DAP*DG)-3', CALCIUM ION, SODIUM ION, ... | | Authors: | Mierzejewska, K, Siwek, W, Czapinska, H, Skowronek, K, Bujnicki, J.M, Bochtler, M. | | Deposit date: | 2013-05-29 | | Release date: | 2014-06-04 | | Last modified: | 2023-09-20 | | Method: | X-RAY DIFFRACTION (2.35 Å) | | Cite: | Structural basis of the methylation specificity of R.DpnI.
Nucleic Acids Res., 42, 2014
|
|
8Q6P
 | | X. laevis CMG dimer bound to dimeric DONSON - MCM ATPase | | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, DNA replication licensing factor mcm2, DNA replication licensing factor mcm4-B, ... | | Authors: | Butryn, A, Cvetkovic, M.A, Costa, A. | | Deposit date: | 2023-08-14 | | Release date: | 2023-10-18 | | Last modified: | 2023-11-29 | | Method: | ELECTRON MICROSCOPY (3.53 Å) | | Cite: | The structural mechanism of dimeric DONSON in replicative helicase activation.
Mol.Cell, 83, 2023
|
|
7R5R
 | | Structure of the human CCAN CENP-A alpha-satellite complex | | Descriptor: | Centromere protein C, DNA (171-MER), Histone H2A type 1-C, ... | | Authors: | Yatskevich, S, Muir, K.W, Bellini, D, Zhang, Z, Yang, J, Tischer, T, Predin, M, Dendooven, T, McLaughlin, S.H, Barford, D. | | Deposit date: | 2022-02-11 | | Release date: | 2022-04-27 | | Last modified: | 2024-07-17 | | Method: | ELECTRON MICROSCOPY (2.44 Å) | | Cite: | Structure of the human inner kinetochore bound to a centromeric CENP-A nucleosome.
Science, 376, 2022
|
|
2DLJ
 | |
8G86
 | | Human Oct4 bound to nucleosome with human nMatn1 sequence (focused refinement of nucleosome) | | Descriptor: | Histone H2A, Histone H2B, Histone H3, ... | | Authors: | Sinha, K.K, Bilokapic, S, Du, Y, Malik, D, Halic, M. | | Deposit date: | 2023-02-17 | | Release date: | 2023-03-22 | | Last modified: | 2024-06-19 | | Method: | ELECTRON MICROSCOPY (2.3 Å) | | Cite: | Histone modifications regulate pioneer transcription factor cooperativity.
Nature, 619, 2023
|
|
8QBM
 | |
