3PNC
Ternary crystal structure of a polymerase lambda variant with a GT mispair at the primer terminus and sodium at catalytic metal site
Summary for 3PNC
Entry DOI | 10.2210/pdb3pnc/pdb |
Related | 3PML 3PMN |
Descriptor | DNA polymerase lambda, 5'-D(*CP*AP*GP*TP*AP*G)-3', 5'-D(*CP*GP*GP*CP*CP*TP*TP*AP*CP*TP*G)-3', ... (9 entities in total) |
Functional Keywords | protein-dna complex, lyase, transferase, dna, transferase-dna complex, transferase/dna |
Biological source | Homo sapiens (human) |
Cellular location | Nucleus: Q9UGP5 |
Total number of polymer chains | 4 |
Total formula weight | 43806.90 |
Authors | Bebenek, K.,Pedersen, L.C.,Kunkel, T.A. (deposition date: 2010-11-18, release date: 2011-02-02, Last modification date: 2024-02-21) |
Primary citation | Bebenek, K.,Pedersen, L.C.,Kunkel, T.A. Replication infidelity via a mismatch with Watson-Crick geometry. Proc.Natl.Acad.Sci.USA, 108:1862-1867, 2011 Cited by PubMed: 21233421DOI: 10.1073/pnas.1012825108 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2 Å) |
Structure validation
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