PDB: 47038 resultsInfo pagesStatus searchChemie searchBIRD

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4GOO	Crystal Structure of E. coli DNA Adenine Methyltransferase in Complex with Benzothiophene Aza-SAM Descriptor: 5'-{[(3S)-3-amino-3-carboxypropyl][2-(1-benzothiophen-3-yl)ethyl]amino}-5'-deoxyadenosine, DNA adenine methylase Authors: Harmer, J.E, Roach, P.L. Deposit date: 2012-08-20 Release date: 2014-02-26 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (2.7 Å) Cite: Structural Basis of Selective N-6 adenine methyltransferase Inhibition by Transition State Mimic To be published
3JC6	Structure of the eukaryotic replicative CMG helicase and pumpjack motion Descriptor: Cell division control protein 45, DNA replication complex GINS protein PSF1, DNA replication complex GINS protein PSF2, ... Authors: Li, H, Bai, L, Yuan, Z, Sun, J, Georgescu, R.E, Liu, J, O'Donnell, M.E. Deposit date: 2015-11-24 Release date: 2016-02-10 Last modified: 2018-07-18 Method: ELECTRON MICROSCOPY (3.7 Å) Cite: Structure of the eukaryotic replicative CMG helicase suggests a pumpjack motion for translocation. Nat.Struct.Mol.Biol., 23, 2016
3JC7	Structure of the eukaryotic replicative CMG helicase and pumpjack motion Descriptor: Cell division control protein 45, DNA replication complex GINS protein PSF1, DNA replication complex GINS protein PSF2, ... Authors: Li, H, Bai, L, Yuan, Z, Sun, J, Georgescu, R.E, Liu, J, O'Donnell, M.E. Deposit date: 2015-11-24 Release date: 2016-02-10 Last modified: 2024-10-30 Method: ELECTRON MICROSCOPY (4.8 Å) Cite: Structure of the eukaryotic replicative CMG helicase suggests a pumpjack motion for translocation. Nat.Struct.Mol.Biol., 23, 2016
8B3G	C(N)RL4CSA-UVSSA-E2-ubiquitin complex. Descriptor: Cullin-4A, DNA damage-binding protein 1, DNA excision repair protein ERCC-8, ... Authors: Kokic, G, Cramer, P. Deposit date: 2022-09-16 Release date: 2024-09-04 Method: ELECTRON MICROSCOPY (4.4 Å) Cite: Structural basis for RNA polymerase II ubiquitylation and inactivation in transcription-coupled repair. Nat.Struct.Mol.Biol., 31, 2024
7Z7E	Crystal structure of p63 DNA binding domain in complex with inhibitory DARPin G4 Descriptor: DARPIN, Isoform 4 of Tumor protein 63, ZINC ION Authors: Strubel, A, Gebel, J, Chaikuad, A, Muenick, P, Doetsch, V. Deposit date: 2022-03-15 Release date: 2022-06-29 Last modified: 2024-01-31 Method: X-RAY DIFFRACTION (1.8 Å) Cite: Designed Ankyrin Repeat Proteins as a tool box for analyzing p63. Cell Death Differ., 29, 2022
1W7A	ATP bound MutS Descriptor: 5'-D(*AP*GP*CP*TP*GP*CP*CP*AP*GP*GP *CP*AP*CP*CP*AP*GP*TP*GP*TP*CP*AP*GP*CP*GP*TP*CP*CP*TP* AP*T)-3', 5'-D(*AP*TP*AP*GP*GP*AP*CP*GP*CP*TP *GP*AP*CP*AP*CP*TP*GP*GP*TP*GP*CP*TP*TP*GP*GP*CP*AP*GP* CP*T)-3', ADENOSINE-5'-TRIPHOSPHATE, ... Authors: Lamers, M.H, Georgijevic, D, Lebbink, J, Winterwerp, H.H.K, Agianian, B, de Wind, N, Sixma, T.K. Deposit date: 2004-08-31 Release date: 2004-09-10 Last modified: 2023-12-13 Method: X-RAY DIFFRACTION (2.27 Å) Cite: ATP Increases the Affinity between Muts ATPase Domains: Implications for ATP Hydrolysis and Conformational Changes J.Biol.Chem., 279, 2004
2K6L	The solution structure of XACb0070 from Xanthonomas axonopodis pv citri reveals this new protein is a member of the RHH family of transcriptional repressors Descriptor: Putative uncharacterized protein Authors: Gallo, M, Cicero, D.O, Amata, I, Eliseo, T, Paci, M, Spisni, A, Ferrari, E, Pertinhez, T.A, Farah, C.S. Deposit date: 2008-07-11 Release date: 2009-06-16 Last modified: 2024-05-29 Method: SOLUTION NMR Cite: The solution structure reveals that XACb0070 from the plant pathogen Xanthomonas citri belongs to the RHH superfamily of bacterial DNA-binding proteins To be Published
1EYF	REFINED STRUCTURE OF THE DNA METHYL PHOSPHOTRIESTER REPAIR DOMAIN OF E. COLI ADA Descriptor: ADA REGULATORY PROTEIN, ZINC ION Authors: Lin, Y, Dotsch, V, Wintner, T, Peariso, K, Myers, L.C, Penner-Hahn, J.E, Verdine, G.L, Wagner, G. Deposit date: 2000-05-06 Release date: 2003-09-09 Last modified: 2024-05-22 Method: SOLUTION NMR Cite: Structural basis for the functional switch of the E. coli Ada protein Biochemistry, 40, 2001
3PML	crystal structure of a polymerase lambda variant with a dGTP analog opposite a templating T Descriptor: 2'-deoxy-5'-O-[(R)-hydroxy{[(S)-hydroxy(phosphonooxy)phosphoryl]methyl}phosphoryl]guanosine, 5'-D(*CP*AP*GP*TP*AP*C)-3', 5'-D(*CP*GP*GP*CP*TP*GP*TP*AP*CP*TP*G)-3', ... Authors: Bebenek, K, Pedersen, L.C, Kunkel, T.A. Deposit date: 2010-11-17 Release date: 2011-01-26 Last modified: 2017-11-08 Method: X-RAY DIFFRACTION (2.6 Å) Cite: Replication infidelity via a mismatch with Watson-Crick geometry. Proc.Natl.Acad.Sci.USA, 108, 2011
8VCT	CyoEM structure of the TnsC(1-503)-TnsD(1-318)-DNA complex in a 6:2:1 stoichiometry from E. coli Tn7 bound to ATPgS and ADP Descriptor: ADENOSINE-5'-DIPHOSPHATE, DNA (50-MER), MAGNESIUM ION, ... Authors: Shen, Y, Guarne, A. Deposit date: 2023-12-14 Release date: 2024-07-31 Method: ELECTRON MICROSCOPY (3.83 Å) Cite: Assembly of the Tn7 targeting complex by a regulated stepwise process. Mol.Cell, 84, 2024
5HOO	Crystal structure of the Mos1 Strand Transfer Complex Descriptor: MAGNESIUM ION, Mariner Mos1 transposase, Mos1 IR DNA NTS, ... Authors: Richardson, J.M, Morris, E.R. Deposit date: 2016-01-19 Release date: 2016-06-01 Last modified: 2024-11-06 Method: X-RAY DIFFRACTION (3.3 Å) Cite: A bend, flip and trap mechanism for transposon integration. Elife, 5, 2016
8D80	Cereblon~DDB1 bound to Iberdomide and Ikaros ZF1-2-3 Descriptor: (3S)-3-[4-({4-[(morpholin-4-yl)methyl]phenyl}methoxy)-1-oxo-1,3-dihydro-2H-isoindol-2-yl]piperidine-2,6-dione, DNA damage-binding protein 1, DNA-binding protein Ikaros, ... Authors: Watson, E.R, Lander, G.C. Deposit date: 2022-06-07 Release date: 2022-07-20 Last modified: 2024-06-12 Method: ELECTRON MICROSCOPY (3.6 Å) Cite: Molecular glue CELMoD compounds are regulators of cereblon conformation. Science, 378, 2022
4ZTD	Crystal Structure of Human PCNA in complex with a TRAIP peptide Descriptor: ALA-GLY-ALA-GLY-ALA, ALA-PHE-GLN-ALA-LYS-LEU-ASP-THR-PHE-LEU-TRP-SER, Proliferating cell nuclear antigen Authors: Montoya, G, Mortuza, G.B, Blanco, F.J, Ibanez de Opakua, A. Deposit date: 2015-05-14 Release date: 2015-12-16 Last modified: 2024-01-10 Method: X-RAY DIFFRACTION (2.199 Å) Cite: TRAIP is a PCNA-binding ubiquitin ligase that protects genome stability after replication stress. J.Cell Biol., 212, 2016
4XPC	Crystal structure of 5'- CTTATAAATTTATAAG in a host-guest complex Descriptor: 1,2-ETHANEDIOL, DNA (5'-D(*CP*TP*TP*AP*TP*AP*AP*A)-3'), DNA (5'-D(P*TP*TP*TP*AP*TP*AP*AP*G)-3'), ... Authors: Georgiadis, M.M, Singh, I. Deposit date: 2015-01-16 Release date: 2015-05-27 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (1.68 Å) Cite: Structural basis for a six nucleotide genetic alphabet. J. Am. Chem. Soc., 137, 2015
4XPE	Crystal structure of 5'-CTTATGGGCCCATAAG in a host-guest complex Descriptor: 1,2-ETHANEDIOL, DNA (5'-D(*CP*TP*TP*AP*TP*GP*GP*G)-3'), DNA (5'-D(P*CP*CP*CP*AP*TP*AP*AP*G)-3'), ... Authors: Georgiadis, M.M, Singh, I. Deposit date: 2015-01-16 Release date: 2015-05-27 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (1.78 Å) Cite: Structural basis for a six nucleotide genetic alphabet. J. Am. Chem. Soc., 137, 2015
5YIU	Caulobacter crescentus GcrA DNA-binding domain (DBD) Descriptor: Cell cycle regulatory protein GcrA Authors: Wu, X, Zhang, Y. Deposit date: 2017-10-06 Release date: 2018-03-21 Last modified: 2023-11-22 Method: X-RAY DIFFRACTION (1.42 Å) Cite: Structural insights into the unique mechanism of transcription activation by Caulobacter crescentus GcrA. Nucleic Acids Res., 46, 2018
2ZTD	MtRuvA Form III Descriptor: GLYCEROL, Holliday junction ATP-dependent DNA helicase ruvA Authors: Prabu, J.R, Thamotharan, S, Khanduja, J.S, Chandra, N.R, Muniyappa, K, Vijayan, M. Deposit date: 2008-10-01 Release date: 2009-05-05 Last modified: 2023-11-01 Method: X-RAY DIFFRACTION (2.4 Å) Cite: Crystallographic and modelling studies on Mycobacterium tuberculosis RuvA Additional role of RuvB-binding domain and inter species variability Biochim.Biophys.Acta, 1794, 2009
8GLW	CryoEM structure of the TnsC(1-503)-TnsD(1-318)-DNA complex in a 7:2:1 stoichiometry from E. coli Tn7 Descriptor: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, DNA (50-MER), ... Authors: Shen, Y, Guarne, A. Deposit date: 2023-03-23 Release date: 2024-07-31 Method: ELECTRON MICROSCOPY (3.51 Å) Cite: Assembly of the Tn7 targeting complex by a regulated stepwise process. Mol.Cell, 84, 2024
8GLX	CryoEM structure of the TnsC(1-503)-TnsD(1-318)-DNA complex in a 6:2:1 stoichiometry from E. coli Tn7 Descriptor: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, DNA (50-MER), ... Authors: Shen, Y, Guarne, A. Deposit date: 2023-03-23 Release date: 2024-07-31 Method: ELECTRON MICROSCOPY (3.88 Å) Cite: Assembly of the Tn7 targeting complex by a regulated stepwise process. Mol.Cell, 84, 2024
8Q56	PglX methyltransferase of Salmonella BREX phage defence system (aka BrxX) bound to inhibitor Ocr Descriptor: Protein Ocr, S-ADENOSYLMETHIONINE, site-specific DNA-methyltransferase (adenine-specific) Authors: Went, S.C, Blower, T.R. Deposit date: 2023-08-08 Release date: 2024-08-21 Last modified: 2024-09-04 Method: X-RAY DIFFRACTION (3.5 Å) Cite: Structure and rational engineering of the PglX methyltransferase and specificity factor for BREX phage defence. Nat Commun, 15, 2024
2ZTE	MtRuvA Form IV Descriptor: Holliday junction ATP-dependent DNA helicase ruvA Authors: Prabu, J.R, Thamotharan, S, Khanduja, J.S, Chandra, N.R, Muniyappa, K, Vijayan, M. Deposit date: 2008-10-01 Release date: 2009-05-05 Last modified: 2023-11-01 Method: X-RAY DIFFRACTION (3.2 Å) Cite: Crystallographic and modelling studies on Mycobacterium tuberculosis RuvA Additional role of RuvB-binding domain and inter species variability Biochim.Biophys.Acta, 1794, 2009
4A0A	Structure of hsDDB1-drDDB2 bound to a 16 bp CPD-duplex (pyrimidine at D-1 position) at 3.6 A resolution (CPD 3) Descriptor: 5'-D(*CP*CP*TP*GP*CP*TP*CP*CP*TP*TP*TP*CP*AP*CP*CP*C)-3', 5'-D(*GP*GP*TP*GP*AP*AP*AP*(TTD)P*AP*GP*CP*AP*GP*DGP)-3', CALCIUM ION, ... Authors: Scrima, A, Fischer, E.S, Iwai, S, Gut, H, Thoma, N.H. Deposit date: 2011-09-08 Release date: 2011-11-30 Last modified: 2023-12-20 Method: X-RAY DIFFRACTION (3.6 Å) Cite: The Molecular Basis of Crl4(Ddb2/Csa) Ubiquitin Ligase Architecture, Targeting, and Activation Cell(Cambridge,Mass.), 147, 2011
8OUY	Human RAD51B-RAD51C-RAD51D-XRCC2 (BCDX2) complex, 3.4 A resolution Descriptor: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, DNA repair protein RAD51 homolog 2, ... Authors: Greenhough, L.A, Liang, C.C, West, S.C. Deposit date: 2023-04-25 Release date: 2023-06-21 Last modified: 2024-07-24 Method: ELECTRON MICROSCOPY (3.4 Å) Cite: Structure and function of the RAD51B-RAD51C-RAD51D-XRCC2 tumour suppressor. Nature, 619, 2023
1QLN	STRUCTURE OF A TRANSCRIBING T7 RNA POLYMERASE INITIATION COMPLEX Descriptor: BACTERIOPHAGE T7 RNA POLYMERASE, DNA (5- D (P*CP*TP*CP*CP*CP*TP*AP*TP*AP*GP*TP*GP*AP*GP*TP*CP*GP*TP* AP*TP*TP*A)-3), DNA (5-D(P*TP*AP*AP*TP*AP*CP*GP*AP*CP*TP*CP*AP*CP*TP*A)-3), ... Authors: Cheetham, G.M.T, Steitz, T.A. Deposit date: 1999-09-01 Release date: 2000-02-04 Last modified: 2023-12-13 Method: X-RAY DIFFRACTION (2.4 Å) Cite: Structure of a Transcribing T7 RNA Polymerase Initiation Complex Science, 286, 1999
2ZTC	MtRuvA Form II Descriptor: GLYCEROL, Holliday junction ATP-dependent DNA helicase ruvA Authors: Prabu, J.R, Thamotharan, S, Khanduja, J.S, Chandra, N.R, Muniyappa, K, Vijayan, M. Deposit date: 2008-10-01 Release date: 2009-05-05 Last modified: 2023-11-01 Method: X-RAY DIFFRACTION (2.8 Å) Cite: Crystallographic and modelling studies on Mycobacterium tuberculosis RuvA Additional role of RuvB-binding domain and inter species variability Biochim.Biophys.Acta, 1794, 2009

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