Crystal Structure of Human PCNA in complex with a TRAIP peptide

Summary for 4ZTD

DescriptorProliferating cell nuclear antigen, ALA-PHE-GLN-ALA-LYS-LEU-ASP-THR-PHE-LEU-TRP-SER, ALA-GLY-ALA-GLY-ALA, ... (4 entities in total)
Functional Keywordspcna, traip, complex, replication
Biological sourceHomo sapiens (Human)
Cellular locationNucleus  P12004
Total number of polymer chains6
Total molecular weight86915.1
Montoya, G.,Mortuza, G.B.,Blanco, F.J.,Ibanez de Opakua, A. (deposition date: 2015-05-14, release date: 2015-12-16, Last modification date: 2016-01-13)
Primary citation
Hoffmann, S.,Smedegaard, S.,Nakamura, K.,Mortuza, G.B.,Raschle, M.,Ibanez de Opakua, A.,Oka, Y.,Feng, Y.,Blanco, F.J.,Mann, M.,Montoya, G.,Groth, A.,Bekker-Jensen, S.,Mailand, N.
TRAIP is a PCNA-binding ubiquitin ligase that protects genome stability after replication stress.
J.Cell Biol., 212:63-75, 2016
PubMed: 26711499 (PDB entries with the same primary citation)
DOI: 10.1083/jcb.201506071
MImport into Mendeley
Experimental method

Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.24591.5%7.6%6.5%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution

More Asymmetric unit images

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