4GOO

Crystal Structure of E. coli DNA Adenine Methyltransferase in Complex with Benzothiophene Aza-SAM

Summary for 4GOO

• Entry DOI: 10.2210/pdb4goo/pdb
• Related: 4GBE 4GOL 4GOM 4GON
• Descriptor: DNA adenine methylase, 5'-{[(3S)-3-amino-3-carboxypropyl][2-(1-benzothiophen-3-yl)ethyl]amino}-5'-deoxyadenosine (3 entities in total)
• Functional Keywords: transferase, methylation
• Biological source: Escherichia coli
• Total number of polymer chains: 3
• Total formula weight: 98013.62

Authors

Harmer, J.E.,Roach, P.L. (deposition date: 2012-08-20, release date: 2014-02-26, Last modification date: 2024-02-28)

• Primary citation: Harmer, J.E.,McKelvie, J.C.,Hobley, G.,Roach, P.L.; Structural Basis of Selective N-6 adenine methyltransferase Inhibition by Transition State Mimic; To be published,

Experimental method

X-RAY DIFFRACTION (2.7 Å)