3PML

crystal structure of a polymerase lambda variant with a dGTP analog opposite a templating T

Summary for 3PML

• Entry DOI: 10.2210/pdb3pml/pdb
• Related: 3GMH 3GMI 3PMH 3PMN 3PNC
• Descriptor: DNA polymerase lambda, 5'-D(*CP*GP*GP*CP*TP*GP*TP*AP*CP*TP*G)-3', 5'-D(P*GP*CP*CP*G)-3', ... (8 entities in total)
• Functional Keywords: protein-dna complex, lyase, transferase, dna, transferase-dna complex, transferase/dna
• Biological source: Homo sapiens (human)
• Cellular location: Nucleus : Q9UGP5
• Total number of polymer chains: 8
• Total formula weight: 87349.15

Authors

Bebenek, K.,Pedersen, L.C.,Kunkel, T.A. (deposition date: 2010-11-17, release date: 2011-01-26, Last modification date: 2017-11-08)

• Primary citation: Bebenek, K.,Pedersen, L.C.,Kunkel, T.A.; Replication infidelity via a mismatch with Watson-Crick geometry.; Proc.Natl.Acad.Sci.USA, 108:1862-1867, 2011; PubMed: 21233421; DOI: 10.1073/pnas.1012825108

Experimental method

X-RAY DIFFRACTION (2.6 Å)