7Z7E
Crystal structure of p63 DNA binding domain in complex with inhibitory DARPin G4
Summary for 7Z7E
Entry DOI | 10.2210/pdb7z7e/pdb |
Descriptor | Isoform 4 of Tumor protein 63, DARPIN, ZINC ION, ... (4 entities in total) |
Functional Keywords | p63 dbd, darpin, inhibitor, transcription |
Biological source | Homo sapiens (human) More |
Total number of polymer chains | 2 |
Total formula weight | 39727.22 |
Authors | Strubel, A.,Gebel, J.,Chaikuad, A.,Muenick, P.,Doetsch, V. (deposition date: 2022-03-15, release date: 2022-06-29, Last modification date: 2024-01-31) |
Primary citation | Strubel, A.,Munick, P.,Chaikuad, A.,Dreier, B.,Schaefer, J.,Gebel, J.,Osterburg, C.,Tuppi, M.,Schafer, B.,Knapp, S.,Pluckthun, A.,Dotsch, V. Designed Ankyrin Repeat Proteins as a tool box for analyzing p63. Cell Death Differ., 29:2445-2458, 2022 Cited by PubMed: 35717504DOI: 10.1038/s41418-022-01030-y PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.8 Å) |
Structure validation
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