7Z7E

Crystal structure of p63 DNA binding domain in complex with inhibitory DARPin G4

Summary for 7Z7E

• Entry DOI: 10.2210/pdb7z7e/pdb
• Descriptor: Isoform 4 of Tumor protein 63, DARPIN, ZINC ION, ... (4 entities in total)
• Functional Keywords: p63 dbd, darpin, inhibitor, transcription
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 2
• Total formula weight: 39727.22

Authors

Strubel, A.,Gebel, J.,Chaikuad, A.,Muenick, P.,Doetsch, V. (deposition date: 2022-03-15, release date: 2022-06-29, Last modification date: 2024-01-31)

• Primary citation: Strubel, A.,Munick, P.,Chaikuad, A.,Dreier, B.,Schaefer, J.,Gebel, J.,Osterburg, C.,Tuppi, M.,Schafer, B.,Knapp, S.,Pluckthun, A.,Dotsch, V.; Designed Ankyrin Repeat Proteins as a tool box for analyzing p63.; Cell Death Differ., 29:2445-2458, 2022; PubMed: 35717504; DOI: 10.1038/s41418-022-01030-y

Experimental method

X-RAY DIFFRACTION (1.8 Å)