7Z7E
Crystal structure of p63 DNA binding domain in complex with inhibitory DARPin G4
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Isoform 4 of Tumor protein 63 | polymer | 204 | 22752.9 | 1 | UniProt (Q9H3D4) Pfam (PF00870) | Homo sapiens (human) | p63,Chronic ulcerative stomatitis protein,CUSP,Keratinocyte transcription factor KET,Transformation-related protein 63,TP63,Tumor protein p73-like,p73L,p40,p51 |
| 2 | B (B) | DARPIN | polymer | 159 | 16908.9 | 1 | synthetic construct | ||
| 3 | C (A) | ZINC ION | non-polymer | 65.4 | 1 | Chemie (ZN) | |||
| 4 | D, E (A, B) | water | water | 18.0 | 186 | Chemie (HOH) |
Sequence modifications
A: 124 - 325 (UniProt: Q9H3D4)
| PDB | External Database | Details |
|---|---|---|
| Gly 122 | - | expression tag |
| Ser 123 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 39661.8 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 65.4 | |
| All* | Total formula weight | 39727.2 |
