7Z7E
Crystal structure of p63 DNA binding domain in complex with inhibitory DARPin G4
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | Isoform 4 of Tumor protein 63 | polymer | 204 | 22752.9 | 1 | UniProt (Q9H3D4) Pfam (PF00870) In PDB | Homo sapiens (human) | p63,Chronic ulcerative stomatitis protein,CUSP,Keratinocyte transcription factor KET,Transformation-related protein 63,TP63,Tumor protein p73-like,p73L,p40,p51 |
2 | B | DARPIN | polymer | 159 | 16908.9 | 1 | synthetic construct | ||
3 | A | ZINC ION | non-polymer | 65.4 | 1 | Chemie (ZN) | |||
4 | water | water | 18.0 | 186 | Chemie (HOH) |
Sequence modifications
A: 124 - 325 (UniProt: Q9H3D4)
PDB | External Database | Details |
---|---|---|
Gly 122 | - | expression tag |
Ser 123 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 2 |
Total formula weight | 39661.8 | |
Non-Polymers* | Number of molecules | 1 |
Total formula weight | 65.4 | |
All* | Total formula weight | 39727.2 |