PDB: 83630 resultsInfo pagesStatus searchChemie searchBIRD

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4MYL	Crystal structure of Trypanosoma cruzi Formiminoglutamase (oxidized) at pH 4.6 Descriptor: Formiminoglutamase Authors: Hai, Y, Dugery, R.J, Healy, D, Christianson, D.W. Deposit date: 2013-09-27 Release date: 2013-11-27 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (1.531 Å) Cite: Formiminoglutamase from trypanosoma cruzi is an arginase-like manganese metalloenzyme. Biochemistry, 52, 2013
4MYF	Crystal structure of Trypanosoma cruzi formiminoglutamase(oxidized) with Mn2+2 at pH 6.0 Descriptor: Formiminoglutamase, MANGANESE (II) ION Authors: Hai, Y, Dugery, R.J, Healy, D, Christianson, D.W. Deposit date: 2013-09-27 Release date: 2013-11-27 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (1.799 Å) Cite: Formiminoglutamase from trypanosoma cruzi is an arginase-like manganese metalloenzyme. Biochemistry, 52, 2013
4DE5	Pantothenate synthetase in complex with fragment 6 Descriptor: (2S)-2,3-dihydro-1,4-benzodioxine-2-carboxylic acid, 1,2-ETHANEDIOL, ETHANOL, ... Authors: Silvestre, H.L. Deposit date: 2012-01-19 Release date: 2013-03-06 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (2.25 Å) Cite: Integrated biophysical approach to fragment screening and validation for fragment-based lead discovery. Proc.Natl.Acad.Sci.USA, 110, 2013
4DDM	Pantothenate synthetase in complex with 2,1,3-benzothiadiazole-5-carboxylic acid Descriptor: 1,2-ETHANEDIOL, 2,1,3-benzothiadiazole-5-carboxylic acid, ETHANOL, ... Authors: Silvestre, H.L. Deposit date: 2012-01-18 Release date: 2013-02-13 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (1.83 Å) Cite: Integrated biophysical approach to fragment screening and validation for fragment-based lead discovery. Proc.Natl.Acad.Sci.USA, 110, 2013
4DDH	Pantothenate synthetase in complex with 6-methoxy-1-benzofuran-3-yl acetic acid Descriptor: (6-methoxy-1-benzofuran-3-yl)acetic acid, 1,2-ETHANEDIOL, ETHANOL, ... Authors: Silvestre, H.L. Deposit date: 2012-01-18 Release date: 2013-02-13 Last modified: 2023-09-13 Method: X-RAY DIFFRACTION (2.07 Å) Cite: Integrated biophysical approach to fragment screening and validation for fragment-based lead discovery. Proc.Natl.Acad.Sci.USA, 110, 2013
4DDK	Pantothenate synthetase in complex with 1,3-benzodioxole-5-carboxylic acid Descriptor: 1,2-ETHANEDIOL, 1,3-benzodioxole-5-carboxylic acid, ETHANOL, ... Authors: Silvestre, H.L. Deposit date: 2012-01-18 Release date: 2013-02-13 Last modified: 2023-09-13 Method: X-RAY DIFFRACTION (1.75 Å) Cite: Integrated biophysical approach to fragment screening and validation for fragment-based lead discovery. Proc.Natl.Acad.Sci.USA, 110, 2013
6DIG	Crystal structure of DQA1*01:02/DQB1*06:02 in complex with a hypocretin peptide Descriptor: 13-mer peptide: ALA-GLY-ASN-HIS-ALA-ALA-GLY-ILE-LEU-THR-LEU-GLY-LYS, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... Authors: Birtley, J.R, Stern, L.J, Mellins, E.D, Jiang, W. Deposit date: 2018-05-23 Release date: 2019-05-08 Last modified: 2023-10-11 Method: X-RAY DIFFRACTION (2 Å) Cite: In vivo clonal expansion and phenotypes of hypocretin-specific CD4+T cells in narcolepsy patients and controls. Nat Commun, 10, 2019
6AIM	Cab2 mutant H337A complex with phosphopantothenate-cysteine Descriptor: N-[(2R)-2-hydroxy-3,3-dimethyl-4-(phosphonooxy)butanoyl]-beta-alanyl-L-cysteine, Phosphopantothenate--cysteine ligase CAB2 Authors: Zheng, P, Zhu, Z. Deposit date: 2018-08-24 Release date: 2019-03-20 Last modified: 2023-11-22 Method: X-RAY DIFFRACTION (2.04 Å) Cite: Crystallographic Analysis of the Catalytic Mechanism of Phosphopantothenoylcysteine Synthetase from Saccharomyces cerevisiae. J. Mol. Biol., 431, 2019
4MYK	Crystal structure of Trypanosoma cruzi formiminoglutamase (oxidized) with Mn2+2 at pH 8.5 Descriptor: Formiminoglutamase, MANGANESE (II) ION Authors: Hai, Y, Dugery, R.J, Healy, D, Christianson, D.W. Deposit date: 2013-09-27 Release date: 2013-11-27 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (1.518 Å) Cite: Formiminoglutamase from trypanosoma cruzi is an arginase-like manganese metalloenzyme. Biochemistry, 52, 2013
1HPT	THREE-DIMENSIONAL STRUCTURE OF A RECOMBINANT VARIANT OF HUMAN PANCREATIC SECRETORY TRYPSIN INHIBITOR (KAZAL TYPE) Descriptor: PANCREATIC SECRETORY TRYPSIN INHIBITOR (KAZAL TYPE) VARIANT 3 Authors: Hecht, H.J, Szardenings, M, Collins, J, Schomburg, D. Deposit date: 1992-03-27 Release date: 1993-10-31 Last modified: 2024-10-16 Method: X-RAY DIFFRACTION (2.3 Å) Cite: Three-dimensional structure of a recombinant variant of human pancreatic secretory trypsin inhibitor (Kazal type). J.Mol.Biol., 225, 1992
4MYN	Crystal structure of Trypanosoma cruzi formiminoglutamase N114H variant with Mn2+2 Descriptor: Formiminoglutamase, MANGANESE (II) ION Authors: Hai, Y, Dugery, R.J, Healy, D, Christianson, D.W. Deposit date: 2013-09-27 Release date: 2013-11-27 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (1.799 Å) Cite: Formiminoglutamase from trypanosoma cruzi is an arginase-like manganese metalloenzyme. Biochemistry, 52, 2013
4M38	Crystal structure of Trypanosoma brucei protein arginine methyltransferase 7 complex with AdoHcy and histone H4 peptide Descriptor: Histone H4, Protein arginine N-methyltransferase 7, S-ADENOSYL-L-HOMOCYSTEINE Authors: Wang, C, Zhu, Y, Shi, Y. Deposit date: 2013-08-06 Release date: 2014-04-23 Last modified: 2024-05-29 Method: X-RAY DIFFRACTION (2.2 Å) Cite: Structural determinants for the strict monomethylation activity by trypanosoma brucei protein arginine methyltransferase 7. Structure, 22, 2014
4GIE	Crystal structure of prostaglandin F synthase from Trypanosoma cruzi bound to NADP Descriptor: ACETATE ION, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, Prostaglandin F synthase Authors: Seattle Structural Genomics Center for Infectious Disease (SSGCID) Deposit date: 2012-08-08 Release date: 2012-08-15 Last modified: 2023-09-13 Method: X-RAY DIFFRACTION (1.25 Å) Cite: Structures of prostaglandin F synthase from the protozoa Leishmania major and Trypanosoma cruzi with NADP. Acta Crystallogr F Struct Biol Commun, 71, 2015
3K8C	Complex of Trypanosoma cruzi ribose 5-phosphate isomerase type B with 4-deoxy-4-phospho-D-erythronohydroxamic acid Descriptor: 4-PHOSPHO-D-ERYTHRONOHYDROXAMIC ACID, Ribose 5-phosphate isomerase Authors: Naworyta, A, Mowbray, S.L, Stern, A.L. Deposit date: 2009-10-14 Release date: 2010-10-27 Last modified: 2023-09-06 Method: X-RAY DIFFRACTION (2.1 Å) Cite: Structures of type B ribose 5-phosphate isomerase from Trypanosoma cruzi shed light on the determinants of sugar specificity in the structural family. Febs J., 278, 2011
4FZI	Crystal structure of prostaglandin F synthase from Trypanosoma cruzi Descriptor: GLUTAMIC ACID, Prostaglandin F synthase, SULFATE ION Authors: Seattle Structural Genomics Center for Infectious Disease (SSGCID) Deposit date: 2012-07-06 Release date: 2012-07-18 Last modified: 2023-09-13 Method: X-RAY DIFFRACTION (2.6 Å) Cite: Structures of prostaglandin F synthase from the protozoa Leishmania major and Trypanosoma cruzi with NADP. Acta Crystallogr F Struct Biol Commun, 71, 2015
3K7O	Structure of type B ribose 5-phosphate isomerase from Trypanosoma cruzi Descriptor: Ribose 5-phosphate isomerase Authors: Naworyta, A, Mowbray, S.L, Stern, A.L. Deposit date: 2009-10-13 Release date: 2010-10-27 Last modified: 2023-09-06 Method: X-RAY DIFFRACTION (2 Å) Cite: Structures of type B ribose 5-phosphate isomerase from Trypanosoma cruzi shed light on the determinants of sugar specificity in the structural family. Febs J., 278, 2011
3K7S	Complex of Trypanosoma cruzi ribose 5-phosphate isomerase type B with ribose 5-phosphate Descriptor: 5-O-phosphono-D-ribose, Ribose 5-phosphate isomerase Authors: Naworyta, A, Mowbray, S.L, Stern, A.L. Deposit date: 2009-10-13 Release date: 2010-10-27 Last modified: 2023-09-06 Method: X-RAY DIFFRACTION (1.9 Å) Cite: Structures of type B ribose 5-phosphate isomerase from Trypanosoma cruzi shed light on the determinants of sugar specificity in the structural family. Febs J., 278, 2011
4E40	The haptoglobin-hemoglobin receptor of Trypanosoma congolense Descriptor: Putative uncharacterized protein Authors: Higgins, M.K, Tkachenko, O, Brown, A, Reed, J, Carrington, M. Deposit date: 2012-03-11 Release date: 2013-01-16 Last modified: 2024-10-09 Method: X-RAY DIFFRACTION (1.6 Å) Cite: Structure of the trypanosome haptoglobin-hemoglobin receptor and implications for nutrient uptake and innate immunity. Proc.Natl.Acad.Sci.USA, 110, 2013
3K7P	Structure of mutant of ribose 5-phosphate isomerase type B from Trypanosoma cruzi. Descriptor: PHOSPHATE ION, Ribose 5-phosphate isomerase Authors: Naworyta, A, Mowbray, S.L, Stern, A.L. Deposit date: 2009-10-13 Release date: 2010-10-27 Last modified: 2023-09-06 Method: X-RAY DIFFRACTION (1.4 Å) Cite: Structures of type B ribose 5-phosphate isomerase from Trypanosoma cruzi shed light on the determinants of sugar specificity in the structural family. Febs J., 278, 2011
4V8M	High-resolution cryo-electron microscopy structure of the Trypanosoma brucei ribosome Descriptor: 18S RRNA OF THE SMALL RIBOSOMAL SUBUNIT, 40S RIBOSOMAL PROTEIN S10, PUTATIVE, ... Authors: Hashem, Y, des Georges, A, Fu, J, Buss, S.N, Jossinet, F, Jobe, A, Zhang, Q, Liao, H.Y, Grassucci, R.A, Bajaj, C, Westhof, E, Madison-Antenucci, S, Frank, J. Deposit date: 2012-12-09 Release date: 2014-07-09 Last modified: 2019-12-11 Method: ELECTRON MICROSCOPY (5.57 Å) Cite: High-Resolution Cryo-Electron Microscopy Structure of the Trypanosoma Brucei Ribosome. Nature, 494, 2013
3W5J	Crystal structure of GDP-bound NfeoB from Gallionella capsiferriformans Descriptor: Ferrous iron transport protein B, GLYCEROL, GUANOSINE-5'-DIPHOSPHATE, ... Authors: Deshpande, C.N, McGrath, A.P, Jormakka, M. Deposit date: 2013-01-30 Release date: 2013-04-24 Last modified: 2023-11-08 Method: X-RAY DIFFRACTION (1.932 Å) Cite: Structure of an atypical FeoB G-domain reveals a putative domain-swapped dimer. Acta Crystallogr.,Sect.F, 69, 2013
4DPR	Structure of human Leukotriene A4 hydrolase in complex with inhibitor captopril Descriptor: ACETIC ACID, GLYCEROL, L-CAPTOPRIL, ... Authors: Stsiapanava, A, Haeggstrom, J.Z, Rinaldo-Matthis, A. Deposit date: 2012-02-14 Release date: 2013-02-20 Last modified: 2023-09-13 Method: X-RAY DIFFRACTION (2.02 Å) Cite: Capturing LTA4hydrolase in action: Insights to the chemistry and dynamics of chemotactic LTB4synthesis. Proc. Natl. Acad. Sci. U.S.A., 114, 2017
3JV1	Crystal structure of the Trypanosoma brucei p22 protein Descriptor: P22 protein Authors: Sprehe, M, Read, L.K, Schumacher, M.A. Deposit date: 2009-09-15 Release date: 2010-04-14 Last modified: 2024-02-21 Method: X-RAY DIFFRACTION (2 Å) Cite: Structure of the Trypanosoma brucei p22 protein, a cytochrome oxidase subunit II-specific RNA-editing accessory factor. J.Biol.Chem., 285, 2010
6RFU	In cellulo crystallization of Trypanosoma brucei IMP dehydrogenase enables the identification of ATP and GMP as genuine co-factors Descriptor: ADENOSINE-5'-TRIPHOSPHATE, GUANOSINE-5'-MONOPHOSPHATE, Inosine-5'-monophosphate dehydrogenase Authors: Nass, K, Redecke, L, Perbandt, M, Yefanov, O, Gabdulkhakov, A, Duszenko, M, Chapman, H.N, Betzel, C. Deposit date: 2019-04-16 Release date: 2020-02-19 Last modified: 2024-01-24 Method: X-RAY DIFFRACTION (2.8 Å) Cite: In cellulo crystallization of Trypanosoma brucei IMP dehydrogenase enables the identification of genuine co-factors. Nat Commun, 11, 2020
5ZUH	Solution structure of RRM domain of La protein from Trypanosoma brucei Descriptor: RNA binding protein La-like protein Authors: Shan, F.Z. Deposit date: 2018-05-07 Release date: 2019-05-15 Last modified: 2024-05-01 Method: SOLUTION NMR Cite: A telomerase subunit homolog La protein from Trypanosoma brucei plays an essential role in ribosomal biogenesis. Febs J., 286, 2019

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