4FZI

Crystal structure of prostaglandin F synthase from Trypanosoma cruzi

Summary for 4FZI

• Entry DOI: 10.2210/pdb4fzi/pdb
• Related: 1VBJ 4F40
• Descriptor: Prostaglandin F synthase, GLUTAMIC ACID, SULFATE ION, ... (4 entities in total)
• Functional Keywords: structural genomics, niaid, national institute of allergy and infectious diseases, seattle structural genomics center for infectious disease, ssgcid, prostaglandin d2, trypanosomiasis, eukaryotic pathogen, parasite, nadp+, nadph, rutin, bimatoprost, oxidoreductase
• Biological source: Trypanosoma cruzi
• Cellular location: Cytoplasm : Q4DJ07
• Total number of polymer chains: 2
• Total formula weight: 67574.39

Authors

Seattle Structural Genomics Center for Infectious Disease (SSGCID) (deposition date: 2012-07-06, release date: 2012-07-18, Last modification date: 2023-09-13)

• Primary citation: Moen, S.O.,Fairman, J.W.,Barnes, S.R.,Sullivan, A.,Nakazawa-Hewitt, S.,Van Voorhis, W.C.,Staker, B.L.,Lorimer, D.D.,Myler, P.J.,Edwards, T.E.; Structures of prostaglandin F synthase from the protozoa Leishmania major and Trypanosoma cruzi with NADP.; Acta Crystallogr F Struct Biol Commun, 71:609-614, 2015; PubMed: 25945716; DOI: 10.1107/S2053230X15006883

Experimental method

X-RAY DIFFRACTION (2.6 Å)