4FZI

Crystal structure of prostaglandin F synthase from Trypanosoma cruzi

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	Prostaglandin F synthase	polymer	290	33592.0	2	UniProt (Q4DJ07) Pfam (PF00248)	Trypanosoma cruzi
2	C, D (A, B)	GLUTAMIC ACID	non-polymer		147.1	2	Chemie (GLU)
3	E (B)	SULFATE ION	non-polymer		96.1	1	Chemie (SO4)
4	F, G (A, B)	water	water		18.0	84	Chemie (HOH)

Sequence modifications

A, B: 1 - 282 (UniProt: Q4DJ07)

PDB	External Database	Details
Met -7	-	expression tag
Ala -6	-	expression tag
His -5	-	expression tag
His -4	-	expression tag
His -3	-	expression tag
His -2	-	expression tag
His -1	-	expression tag
His 0	-	expression tag
Val 14	Ala 14	conflict
Tyr 51	Cys 51	conflict
Ser 54	Asn 54	conflict
Arg 57	Lys 57	conflict
Glu 195	Asp 195	conflict
Glu 196	Arg 196	conflict
Ala 197	Thr 197	conflict
Ile 199	Phe 199	conflict
Ala 271	Gly 271	conflict
Asp 272	His 272	conflict

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	67184.1
Non-Polymers*	Number of molecules	3
	Total formula weight	390.3
All*	Total formula weight	67574.4

*Water molecules are not included.