4GIE

Crystal structure of prostaglandin F synthase from Trypanosoma cruzi bound to NADP

Summary for 4GIE

Entry DOI	10.2210/pdb4gie/pdb
Related	4F40 4FZI 4G5D
Descriptor	Prostaglandin F synthase, ACETATE ION, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ... (4 entities in total)
Functional Keywords	structural genomics, niaid, national institute of allergy and infectious diseases, seattle structural genomics center for infectious disease, ssgcid, chagas disease, prostaglandin d2, trypanosomiasis, eukaryotic pathogen, parasite, nadp+, nadph, rutin, bimatoprost, oxidoreductase
Biological source	Trypanosoma cruzi
Cellular location	Cytoplasm : Q4DJ07
Total number of polymer chains	1
Total formula weight	34394.48
Authors	Seattle Structural Genomics Center for Infectious Disease (SSGCID) (deposition date: 2012-08-08, release date: 2012-08-15, Last modification date: 2023-09-13)
Primary citation	Moen, S.O.,Fairman, J.W.,Barnes, S.R.,Sullivan, A.,Nakazawa-Hewitt, S.,Van Voorhis, W.C.,Staker, B.L.,Lorimer, D.D.,Myler, P.J.,Edwards, T.E. Structures of prostaglandin F synthase from the protozoa Leishmania major and Trypanosoma cruzi with NADP. Acta Crystallogr F Struct Biol Commun, 71:609-614, 2015 Cited by PubMed: 25945716 DOI: 10.1107/S2053230X15006883 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.25 Å)

Structure validation