4GIE

Crystal structure of prostaglandin F synthase from Trypanosoma cruzi bound to NADP

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	Prostaglandin F synthase	polymer	290	33592.0	1	UniProt (Q4DJ07) Pfam (PF00248) In PDB	Trypanosoma cruzi
2	A	ACETATE ION	non-polymer		59.0	1	Chemie (ACT)
3	A	NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE	non-polymer		743.4	1	Chemie (NAP)
4		water	water		18.0	413	Chemie (HOH)

Sequence modifications

A: 1 - 282 (UniProt: Q4DJ07)

PDB	External Database	Details
Met -7	-	expression tag
Ala -6	-	expression tag
His -5	-	expression tag
His -4	-	expression tag
His -3	-	expression tag
His -2	-	expression tag
His -1	-	expression tag
His 0	-	expression tag
Val 14	Ala 14	conflict
Tyr 51	Cys 51	conflict
Ser 54	Asn 54	conflict
Arg 57	Lys 57	conflict
Glu 195	Asp 195	conflict
Glu 196	Arg 196	conflict
Ala 197	Thr 197	conflict
Ile 199	Phe 199	conflict
Ala 271	Gly 271	conflict
Asp 272	His 272	conflict

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	33592.0
Non-Polymers*	Number of molecules	2
	Total formula weight	802.4
All*	Total formula weight	34394.5

*Water molecules are not included.