4GIE
Crystal structure of prostaglandin F synthase from Trypanosoma cruzi bound to NADP
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Prostaglandin F synthase | polymer | 290 | 33592.0 | 1 | UniProt (Q4DJ07) Pfam (PF00248) | Trypanosoma cruzi | |
| 2 | B (A) | ACETATE ION | non-polymer | 59.0 | 1 | Chemie (ACT) | |||
| 3 | C (A) | NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | non-polymer | 743.4 | 1 | Chemie (NAP) | |||
| 4 | D (A) | water | water | 18.0 | 413 | Chemie (HOH) |
Sequence modifications
A: 1 - 282 (UniProt: Q4DJ07)
| PDB | External Database | Details |
|---|---|---|
| Met -7 | - | expression tag |
| Ala -6 | - | expression tag |
| His -5 | - | expression tag |
| His -4 | - | expression tag |
| His -3 | - | expression tag |
| His -2 | - | expression tag |
| His -1 | - | expression tag |
| His 0 | - | expression tag |
| Val 14 | Ala 14 | conflict |
| Tyr 51 | Cys 51 | conflict |
| Ser 54 | Asn 54 | conflict |
| Arg 57 | Lys 57 | conflict |
| Glu 195 | Asp 195 | conflict |
| Glu 196 | Arg 196 | conflict |
| Ala 197 | Thr 197 | conflict |
| Ile 199 | Phe 199 | conflict |
| Ala 271 | Gly 271 | conflict |
| Asp 272 | His 272 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 33592.0 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 802.4 | |
| All* | Total formula weight | 34394.5 |
