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7WKV
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BU of 7wkv by Molmil
Crystal structure of human ALKBH5 in complex with 2-oxoglutarate (2OG) and m6A-containing ssRNA
Descriptor: 2-OXOGLUTARIC ACID, MANGANESE (II) ION, RNA (5'-R(P*GP*GP*(6MZ)P*C)-3'), ...
Authors:Kaur, S, McDonough, M.A, Schofield, C.J, Aik, W.S.
Deposit date:2022-01-11
Release date:2022-03-30
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Mechanisms of substrate recognition and N6-methyladenosine demethylation revealed by crystal structures of ALKBH5-RNA complexes.
Nucleic Acids Res., 50, 2022
5YDT
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BU of 5ydt by Molmil
Remodeled Utp30 in 90S pre-ribosome (Mtr4-depleted, Enp1-TAP)
Descriptor: 5' ETS RNA, Ribosome biogenesis protein UTP30, Saccharomyces cerevisiae strain ALI 308 18S ribosomal RNA gene, ...
Authors:Ye, K, Zhu, X, Hu, J.
Deposit date:2017-09-14
Release date:2017-11-01
Last modified:2024-03-27
Method:ELECTRON MICROSCOPY (4.5 Å)
Cite:Structure and RNA recognition of ribosome assembly factor Utp30.
RNA, 23, 2017
7V4G
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BU of 7v4g by Molmil
Crystal structure of human ALKBH5 in complex with m6A-containing ssRNA
Descriptor: GLYCEROL, MANGANESE (II) ION, RNA (5'-R(P*GP*GP*(6MZ)P*C)-3'), ...
Authors:Kaur, S, McDonough, M.A, Schofield, C.J, Aik, W.S.
Deposit date:2021-08-13
Release date:2022-03-30
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Mechanisms of substrate recognition and N6-methyladenosine demethylation revealed by crystal structures of ALKBH5-RNA complexes.
Nucleic Acids Res., 50, 2022
3LQV
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BU of 3lqv by Molmil
Branch Recognition by SF3b14
Descriptor: ADENINE, Pre-mRNA branch site protein p14, Splicing factor 3B subunit 1
Authors:Schellenberg, M.J, MacMillan, A.M.
Deposit date:2010-02-10
Release date:2011-01-26
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.38 Å)
Cite:Branch Recognition by SF3b14
Rna, 17, 2011
6OTJ
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BU of 6otj by Molmil
Crystal Structure of Tyrosyl-tRNA synthetase from Neisseria gonorrhoeae with bound L-Tyr
Descriptor: 1,2-ETHANEDIOL, SULFATE ION, TYROSINE, ...
Authors:Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:2019-05-03
Release date:2019-05-15
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.85 Å)
Cite:Crystal Structure of Tyrosyl-tRNA synthetase from Neisseria gonorrhoeae with bound L-Tyr
to be published
3J5S
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BU of 3j5s by Molmil
EttA binds to ribosome exit site and regulates translation by restricting ribosome and tRNA dynamics
Descriptor: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S7, ...
Authors:Hashem, Y.
Deposit date:2013-11-15
Release date:2014-01-08
Last modified:2024-02-21
Method:ELECTRON MICROSCOPY (7.5 Å)
Cite:EttA regulates translation by binding the ribosomal E site and restricting ribosome-tRNA dynamics.
Nat.Struct.Mol.Biol., 21, 2014
4KR9
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BU of 4kr9 by Molmil
Crystal structure of a 4-thiouridine synthetase - RNA complex at 3.5 Angstrom resolution
Descriptor: Probable tRNA sulfurtransferase, RNA (39-MER)
Authors:Neumann, P, Ficner, R, Lakomek, K.
Deposit date:2013-05-16
Release date:2014-04-23
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (3.5 Å)
Cite:Crystal structure of a 4-thiouridine synthetase-RNA complex reveals specificity of tRNA U8 modification.
Nucleic Acids Res., 42, 2014
8H53
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BU of 8h53 by Molmil
Human asparaginyl-tRNA synthetase in complex with asparagine-AMP
Descriptor: 4-AMINO-1,4-DIOXOBUTAN-2-AMINIUM ADENOSINE-5'-MONOPHOSPHATE, Asparagine--tRNA ligase, cytoplasmic, ...
Authors:Park, J.S, Han, B.W.
Deposit date:2022-10-12
Release date:2023-10-25
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (2.16 Å)
Cite:Reaction hijacking inhibition of Plasmodium falciparum asparagine tRNA synthetase.
Nat Commun, 15, 2024
5FT9
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BU of 5ft9 by Molmil
Arabidopsis thaliana nuclear protein-only RNase P 2 (PRORP2)
Descriptor: PROTEINACEOUS RNASE P 2, ZINC ION
Authors:Fernandez-Millan, P, Pinker, F, Schelcher, C, Gobert, A, Giege, P, Sauter, C.
Deposit date:2016-01-12
Release date:2016-01-27
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (3.05 Å)
Cite:Structures of Arabidopsis Nuclear Rnase P Alone and with tRNA Reveal Plasticities
To be Published
4YYE
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BU of 4yye by Molmil
Crystal structure of the yeast mitochondrial threonyl-tRNA synthetase (MST1) in complex with the canonical tRNAThr and threonyl sulfamoyl adenylate
Descriptor: 5'-O-(N-(L-THREONYL)-SULFAMOYL)ADENOSINE, SULFATE ION, Threonine--tRNA ligase, ...
Authors:Holman, K.M, Simonovic, M.
Deposit date:2015-03-23
Release date:2016-01-06
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.301 Å)
Cite:The crystal structure of yeast mitochondrial ThrRS in complex with the canonical threonine tRNA.
Nucleic Acids Res., 44, 2016
4KR7
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BU of 4kr7 by Molmil
Crystal structure of a 4-thiouridine synthetase - RNA complex with bound ATP
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, Probable tRNA sulfurtransferase, ...
Authors:Neumann, P, Ficner, R, Lakomek, K.
Deposit date:2013-05-16
Release date:2014-04-23
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (3.421 Å)
Cite:Crystal structure of a 4-thiouridine synthetase-RNA complex reveals specificity of tRNA U8 modification.
Nucleic Acids Res., 42, 2014
5NKX
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BU of 5nkx by Molmil
HRSV M2-1 core domain, P3221 crystal form
Descriptor: M2-1
Authors:Almeida Hernandez, Y, Josts, I, Molina, I.G, de Pray-Gay, G, Tidow, H.
Deposit date:2017-04-03
Release date:2018-01-03
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.00008678 Å)
Cite:Structure and stability of the Human respiratory syncytial virus M2-1RNA-binding core domain reveals a compact and cooperative folding unit.
Acta Crystallogr F Struct Biol Commun, 74, 2018
4KR6
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BU of 4kr6 by Molmil
Crystal structure of a 4-thiouridine synthetase - RNA complex
Descriptor: MERCURY (II) ION, Probable tRNA sulfurtransferase, RNA (39-MER)
Authors:Neumann, P, Ficner, R, Lakomek, K.
Deposit date:2013-05-16
Release date:2014-04-23
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.85 Å)
Cite:Crystal structure of a 4-thiouridine synthetase-RNA complex reveals specificity of tRNA U8 modification.
Nucleic Acids Res., 42, 2014
4J7L
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BU of 4j7l by Molmil
Crystal structure of mouse DXO in complex with PRODUCT RNA AND two MAGNESIUM ions
Descriptor: MAGNESIUM ION, Protein Dom3Z, RNA (5'-R(P*UP*UP*UP*UP*U)-3'), ...
Authors:Chang, J.H, Tong, L.
Deposit date:2013-02-13
Release date:2013-03-27
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:A mammalian pre-mRNA 5' end capping quality control mechanism and an unexpected link of capping to pre-mRNA processing.
Mol.Cell, 50, 2013
5W25
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BU of 5w25 by Molmil
Crystal structure of Aspartyl-tRNA synthetase from Mycobacterium tuberculosis complexed with L-Aspartic Acid
Descriptor: ASPARTIC ACID, Aspartate--tRNA(Asp/Asn) ligase, GLUTAMIC ACID, ...
Authors:Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:2017-06-05
Release date:2017-06-14
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (2.65 Å)
Cite:Crystal structure of Aspartyl-tRNA synthetase from Mycobacterium tuberculosis complexed with L-Aspartic Acid
to be published
8FFY
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BU of 8ffy by Molmil
Cryo-electron microscopy structure of human mt-SerRS in complex with mt-tRNA(UGA-TL)
Descriptor: 5'-O-(N-(L-SERYL)-SULFAMOYL)ADENOSINE, Serine--tRNA ligase, mitochondrial, ...
Authors:Hirschi, M, Kuhle, B, Doerfel, L, Schimmel, P, Lander, G.
Deposit date:2022-12-11
Release date:2023-08-23
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:Structural basis for a degenerate tRNA identity code and the evolution of bimodal specificity in human mitochondrial tRNA recognition.
Nat Commun, 14, 2023
6FQ1
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BU of 6fq1 by Molmil
Crystal structure of the RRM12 domain of IMP3
Descriptor: 1,2-ETHANEDIOL, Insulin-like growth factor 2 mRNA-binding protein 3
Authors:Jia, M, Gut, H, Chao, A.J.
Deposit date:2018-02-12
Release date:2018-09-05
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (1.31 Å)
Cite:Structural basis of IMP3 RRM12 recognition of RNA.
RNA, 24, 2018
3U3G
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BU of 3u3g by Molmil
Structure of LC11-RNase H1 Isolated from Compost by Metagenomic Approach: Insight into the Structural Bases for Unusual Enzymatic Properties of Sto-RNase H1
Descriptor: CHLORIDE ION, Ribonuclease H, UNKNOWN LIGAND
Authors:Nguyen, T.N, Angkawidjaja, C, Kanaya, E, Koga, Y, Takano, K, Kanaya, S.
Deposit date:2011-10-05
Release date:2012-03-07
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Activity, stability, and structure of metagenome-derived LC11-RNase H1, a homolog of Sulfolobus tokodaii RNase H1
Protein Sci., 21, 2012
5VL1
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BU of 5vl1 by Molmil
Crystal Structure of Lysyl-tRNA Synthetase from Mycobacterium ulcerans complexed with L-lysine
Descriptor: DI(HYDROXYETHYL)ETHER, LYSINE, Lysine--tRNA ligase, ...
Authors:Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:2017-04-24
Release date:2017-05-10
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Crystal Structure of Lysyl-tRNA Synthetase from Mycobacterium ulcerans complexed with L-lysine
to be published
5JP4
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BU of 5jp4 by Molmil
Crystal structure of S. pombe Dcp1 in complex with the decapping enhancer EDC
Descriptor: Uncharacterized protein C18G6.09c, mRNA-decapping enzyme subunit 1
Authors:Wurm, J.P, Sprangers, R.
Deposit date:2016-05-03
Release date:2016-06-01
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.043 Å)
Cite:The S. pombe mRNA decapping complex recruits cofactors and an Edc1-like activator through a single dynamic surface.
Rna, 22, 2016
1LU3
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BU of 1lu3 by Molmil
Separate Fitting of the Anticodon Loop Region of tRNA (nucleotide 26-42) in the Low Resolution Cryo-EM Map of an EF-Tu Ternary Complex (GDP and Kirromycin) Bound to E. coli 70S Ribosome
Descriptor: PHENYLALANINE TRANSFER RNA
Authors:Valle, M, Sengupta, J, Swami, N.K, Grassucci, R.A, Burkhardt, N, Nierhaus, K.H, Agrawal, R.K, Frank, J.
Deposit date:2002-05-21
Release date:2002-06-26
Last modified:2024-02-14
Method:ELECTRON MICROSCOPY (16.799999 Å)
Cite:Cryo-EM reveals an active role for aminoacyl-tRNA in the accommodation process.
EMBO J., 21, 2002
3SNP
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BU of 3snp by Molmil
Crystal structure analysis of iron regulatory protein 1 in complex with ferritin H IRE RNA
Descriptor: Cytoplasmic aconitate hydratase, ferritin H IRE RNA
Authors:Volz, K, Selezneva, A.I, Walden, W.E.
Deposit date:2011-06-29
Release date:2011-07-27
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structure of dual function iron regulatory protein 1 complexed with ferritin IRE-RNA.
Science, 314, 2006
2HW8
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BU of 2hw8 by Molmil
Structure of ribosomal protein L1-mRNA complex at 2.1 resolution.
Descriptor: 1,4-BUTANEDIOL, 36-MER, 50S ribosomal protein L1, ...
Authors:Tishchenko, S, Nikonova, E, Nikulin, A, Nevskaya, N, Volchkov, S, Piendl, W, Garber, M, Nikonov, S.
Deposit date:2006-08-01
Release date:2006-12-19
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structure of the ribosomal protein L1-mRNA complex at 2.1 A resolution: common features of crystal packing of L1-RNA complexes.
ACTA CRYSTALLOGR.,SECT.D, 62, 2006
1KOG
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BU of 1kog by Molmil
Crystal structure of E. coli threonyl-tRNA synthetase interacting with the essential domain of its mRNA operator
Descriptor: 5'-O-(N-(L-THREONYL)-SULFAMOYL)ADENOSINE, Threonyl-tRNA synthetase, Threonyl-tRNA synthetase mRNA, ...
Authors:Torres-Larrios, A, Dock-Bregeon, A.C, Romby, P, Rees, B, Sankaranarayanan, R, Caillet, J, Springer, M, Ehresmann, C, Ehresmann, B, Moras, D.
Deposit date:2001-12-20
Release date:2002-04-26
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (3.5 Å)
Cite:Structural basis of translational control by Escherichia coli threonyl tRNA synthetase.
Nat.Struct.Biol., 9, 2002
4OLF
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BU of 4olf by Molmil
Crystal Structure of Prolyl-tRNA synthetase (ProRS, Proline--tRNA ligase)from Plasmodium falciparum in complex with Halofuginone and AMPPNP
Descriptor: 1,2-ETHANEDIOL, 7-bromo-6-chloro-3-{3-[(2R,3S)-3-hydroxypiperidin-2-yl]-2-oxopropyl}quinazolin-4(3H)-one, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ...
Authors:Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:2014-01-23
Release date:2015-04-15
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Crystal Structure of Prolyl-tRNA synthetase (ProRS, Proline--tRNA ligase)from Plasmodium falciparum in complex with Halofuginone and AMPPNP
To be Published

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