4OLF
Crystal Structure of Prolyl-tRNA synthetase (ProRS, Proline--tRNA ligase)from Plasmodium falciparum in complex with Halofuginone and AMPPNP
Summary for 4OLF
Entry DOI | 10.2210/pdb4olf/pdb |
Related | 4NCX |
Descriptor | Proline--tRNA ligase, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, 7-bromo-6-chloro-3-{3-[(2R,3S)-3-hydroxypiperidin-2-yl]-2-oxopropyl}quinazolin-4(3H)-one, ... (7 entities in total) |
Functional Keywords | structural genomics, niaid, national institute of allergy and infectious diseases, seattle structural genomics center for infectious disease, ssgcid, prolyl-trna synthetase, ligase |
Biological source | Plasmodium falciparum |
Cellular location | Cytoplasm : Q8I5R7 |
Total number of polymer chains | 1 |
Total formula weight | 61433.38 |
Authors | Seattle Structural Genomics Center for Infectious Disease (SSGCID) (deposition date: 2014-01-23, release date: 2015-04-15, Last modification date: 2023-09-20) |
Primary citation | Dranow, D.M.,Edwards, T.E.,Lorimer, D.,Seattle Structural Genomics Center for Infectious Disease Crystal Structure of Prolyl-tRNA synthetase (ProRS, Proline--tRNA ligase)from Plasmodium falciparum in complex with Halofuginone and AMPPNP To be Published, |
Experimental method | X-RAY DIFFRACTION (2.9 Å) |
Structure validation
Download full validation report