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6JO1
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BU of 6jo1 by Molmil
Structure of the CYP102A1 Haem Domain with N-(S)-Ibuprofenoyl-L-Phenylalanine
Descriptor: (2S)-2-[[(2S)-2-[4-(2-methylpropyl)phenyl]propanoyl]amino]-3-phenyl-propanoic acid, Bifunctional cytochrome P450/NADPH--P450 reductase, DIMETHYL SULFOXIDE, ...
Authors:Stanfield, J.K, Kasai, C, Sugimoto, H, Shiro, Y, Watanabe, Y, Shoji, O.
Deposit date:2019-03-19
Release date:2020-03-18
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Crystals in Minutes: Instant On-Site Microcrystallisation of Various Flavours of the CYP102A1 (P450BM3) Haem Domain.
Angew.Chem.Int.Ed.Engl., 59, 2020
6JOL
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BU of 6jol by Molmil
Crystal structure of PDGFRA in complex with imatinib by co-crystallization
Descriptor: 4-(4-METHYL-PIPERAZIN-1-YLMETHYL)-N-[4-METHYL-3-(4-PYRIDIN-3-YL-PYRIMIDIN-2-YLAMINO)-PHENYL]-BENZAMIDE, Platelet-derived growth factor receptor alpha
Authors:Liang, L, Yan, X.E, Yun, C.H.
Deposit date:2019-03-22
Release date:2020-03-25
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Crystal structure of PDGFRA in complex with imatinib by co-crystallization
To Be Published
7RX2
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BU of 7rx2 by Molmil
afTMEM16 in C22 lipid nanodiscs with MSP1E3 scaffold protein in the presnece of Ca2+
Descriptor: (1R)-2-{[(S)-{[(2S)-2,3-dihydroxypropyl]oxy}(hydroxy)phosphoryl]oxy}-1-[(hexadecanoyloxy)methyl]ethyl (9Z)-octadec-9-enoate, CALCIUM ION, afTMEM16 lipid scramblase
Authors:Falzone, M.E, Accardi, A.
Deposit date:2021-08-21
Release date:2022-05-18
Last modified:2024-06-05
Method:ELECTRON MICROSCOPY (2.7 Å)
Cite:TMEM16 scramblases thin the membrane to enable lipid scrambling.
Nat Commun, 13, 2022
6JOQ
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BU of 6joq by Molmil
Crystal structures of phage NrS-1 N300-dNTPs-Mg2+ complex provide molecular mechanisms for substrate specificity
Descriptor: 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, Primase
Authors:Guo, H.J, Li, M.J, Wu, H, Yu, F, He, J.H.
Deposit date:2019-03-22
Release date:2019-06-26
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Crystal structures of phage NrS-1 N300-dNTPs-Mg2+complex provide molecular mechanisms for substrate specificity.
Biochem.Biophys.Res.Commun., 515, 2019
6JK5
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BU of 6jk5 by Molmil
Ca2+-dependent type II antifreeze protein (Ca2+-free form)
Descriptor: SULFATE ION, Type II antifreeze protein
Authors:Arai, T, Tsuda, S, Kondo, H, Nishimiya, Y.
Deposit date:2019-02-27
Release date:2019-06-26
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (1.25 Å)
Cite:Calcium-Binding Generates the Semi-Clathrate Waters on a Type II Antifreeze Protein to Adsorb onto an Ice Crystal Surface.
Biomolecules, 9, 2019
6JKD
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BU of 6jkd by Molmil
Crystal structure of tetrameric PepTSo2 in I4 space group
Descriptor: Proton:oligopeptide symporter POT family
Authors:Nagamura, R, Fukuda, M, Ishitani, R, Nureki, O.
Deposit date:2019-02-28
Release date:2019-05-15
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (3.9 Å)
Cite:Structural basis for oligomerization of the prokaryotic peptide transporter PepTSo2.
Acta Crystallogr.,Sect.F, 75, 2019
6JKJ
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BU of 6jkj by Molmil
Crystal structure of human SPSB2 in the apo-state
Descriptor: SPRY domain-containing SOCS box protein 2
Authors:Luo, Y, Kuang, Z.
Deposit date:2019-03-01
Release date:2019-07-03
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Crystal structure of the SPRY domain of human SPSB2 in the apo state.
Acta Crystallogr.,Sect.F, 75, 2019
6JKR
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BU of 6jkr by Molmil
Crystal structure of aspartate transcarbamoylase from Trypanosoma cruzi in complex with carbamoyl phosphate (CP)
Descriptor: Aspartate carbamoyltransferase, GLYCEROL, PHOSPHORIC ACID MONO(FORMAMIDE)ESTER
Authors:Matoba, K, Shiba, T, Nara, T, Aoki, T, Nagasaki, S, Hayamizu, R, Honma, T, Tanaka, A, Inoue, M, Matsuoka, S, Balogun, E.O, Inaoka, D.K, Kita, K, Harada, S.
Deposit date:2019-03-01
Release date:2020-03-04
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Crystallographic snapshots of Trypanosoma cruzi aspartate transcarbamoylase revealed an ordered Bi-Bi reaction mechanism
To Be Published
6JOW
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BU of 6jow by Molmil
Exo-beta-D-glucosaminidase from Pyrococcus furiosus
Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, Beta-galactosidase, CALCIUM ION
Authors:Mine, S, Watanabe, M.
Deposit date:2019-03-24
Release date:2020-03-25
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Exo-beta-D-glucosaminidase from Pyrococcus furiosus
To Be Published
6JQ6
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BU of 6jq6 by Molmil
Hatchet Ribozyme Structure soaking with Ir(NH3)6+
Descriptor: IRIDIUM HEXAMMINE ION, RNA (81-MER)
Authors:Ren, A, Zheng, L.
Deposit date:2019-03-29
Release date:2019-06-12
Last modified:2024-03-27
Method:X-RAY DIFFRACTION (2.626 Å)
Cite:Hatchet ribozyme structure and implications for cleavage mechanism.
Proc.Natl.Acad.Sci.USA, 116, 2019
6JQK
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BU of 6jqk by Molmil
Structure of C34M/N36
Descriptor: C34M, N36
Authors:Yu, D.W, Qin, B.
Deposit date:2019-03-31
Release date:2020-04-08
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (1.498 Å)
Cite:Structure of C34M/N36
To Be Published
6JQN
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BU of 6jqn by Molmil
Structure of PaaZ, a bifunctional enzyme in complex with NADP+ and OCoA
Descriptor: Bifunctional protein PaaZ, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, OCTANOYL-COENZYME A
Authors:Gakher, L, Vinothkumar, K.R, Katagihallimath, N, Sowdhamini, R, Sathyanarayanan, N, Cannone, G.
Deposit date:2019-03-31
Release date:2019-09-11
Last modified:2024-03-27
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:Molecular basis for metabolite channeling in a ring opening enzyme of the phenylacetate degradation pathway.
Nat Commun, 10, 2019
6JLF
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BU of 6jlf by Molmil
Crystal structure of a bacterial Bestrophin homolog from Klebsiella pneumoniae D179A mutation - HR
Descriptor: Bestrophin homolog, ZINC ION
Authors:Kittredge, A, Chen, S, Yang, T.
Deposit date:2019-03-05
Release date:2019-11-13
Last modified:2024-05-29
Method:X-RAY DIFFRACTION (2.548 Å)
Cite:Dual Ca2+-dependent gates in human Bestrophin1 underlie disease-causing mechanisms of gain-of-function mutations.
Commun Biol, 2, 2019
7RXH
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BU of 7rxh by Molmil
afTMEM16 in C18 lipid nanodiscs with MSP1E3 scaffold protein in the presence of Ca2+, monomer with extra lipids
Descriptor: (1R)-2-{[(S)-{[(2S)-2,3-dihydroxypropyl]oxy}(hydroxy)phosphoryl]oxy}-1-[(hexadecanoyloxy)methyl]ethyl (9Z)-octadec-9-enoate, CALCIUM ION, afTMEM16 lipid scramblase
Authors:Falzone, M.E, Accardi, A.
Deposit date:2021-08-23
Release date:2022-05-18
Last modified:2024-06-05
Method:ELECTRON MICROSCOPY (2.3 Å)
Cite:TMEM16 scramblases thin the membrane to enable lipid scrambling.
Nat Commun, 13, 2022
6JLQ
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BU of 6jlq by Molmil
Crystal structure of human USP46-WDR48-WDR20 complex
Descriptor: GLYCEROL, PHOSPHATE ION, Ubiquitin carboxyl-terminal hydrolase 46, ...
Authors:Zhu, H, Zhang, T, Ding, J.
Deposit date:2019-03-06
Release date:2019-07-10
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (3.101 Å)
Cite:Structural insights into the activation of USP46 by WDR48 and WDR20.
Cell Discov, 5, 2019
6JM7
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BU of 6jm7 by Molmil
Crystal structure of Ostrinia furnacalis Group IV chitinase
Descriptor: ofchtiv
Authors:Liu, T, Yang, Q.
Deposit date:2019-03-07
Release date:2020-03-11
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (1.572 Å)
Cite:Structure and property of group IV insect chitinase, a potential drug target and biopesticide
Insect Biochem.Mol.Biol., 119, 2020
6JMB
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BU of 6jmb by Molmil
Crystal structure of Ostrinia furnacalis Group IV chitinase in complex with allosamidin
Descriptor: 2-acetamido-2-deoxy-beta-D-allopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-allopyranose, ALLOSAMIZOLINE, ofchtiv-allosamidin
Authors:Liu, T, Yang, Q.
Deposit date:2019-03-07
Release date:2020-03-11
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (1.389 Å)
Cite:Structure and property of group IV insect chitinase, a potential drug target and biopesticide
Insect Biochem.Mol.Biol., 119, 2020
7RX3
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BU of 7rx3 by Molmil
afTMEM16 in C14 lipid nanodiscs with MSP1E3 scaffold protein in the absence of Ca2+
Descriptor: (1R)-2-{[(S)-{[(2S)-2,3-dihydroxypropyl]oxy}(hydroxy)phosphoryl]oxy}-1-[(hexadecanoyloxy)methyl]ethyl (9Z)-octadec-9-enoate, afTMEM16 lipid scramblase
Authors:Falzone, M.E, Accardi, A.
Deposit date:2021-08-21
Release date:2022-05-18
Last modified:2024-06-05
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:TMEM16 scramblases thin the membrane to enable lipid scrambling.
Nat Commun, 13, 2022
6JSA
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BU of 6jsa by Molmil
Crystal structure of the C-terminal domain of HtaA from Corynebacterium glutamicum
Descriptor: Hypothetical membrane protein, PROTOPORPHYRIN IX CONTAINING FE
Authors:Muraki, N, Aono, S.
Deposit date:2019-04-08
Release date:2019-11-20
Last modified:2024-03-27
Method:X-RAY DIFFRACTION (1.3 Å)
Cite:Structural basis for the heme transfer reaction in heme uptake machinery from Corynebacteria.
Chem.Commun.(Camb.), 55, 2019
6JSH
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BU of 6jsh by Molmil
Apo-state Fatty Acid Synthase
Descriptor: Fatty acid synthase subunit alpha, Fatty acid synthase subunit beta
Authors:Qiu, S.W, Liu, S.
Deposit date:2019-04-08
Release date:2019-09-25
Last modified:2024-03-27
Method:ELECTRON MICROSCOPY (5.1 Å)
Cite:Modulation of fatty acid synthase by ATR checkpoint kinase Rad3.
J Mol Cell Biol, 11, 2019
7RXG
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BU of 7rxg by Molmil
afTMEM16 in C18 lipid nanodiscs with MSP1E3 scaffold protein in the presence of Ca2+, full dimer
Descriptor: (1R)-2-{[(S)-{[(2S)-2,3-dihydroxypropyl]oxy}(hydroxy)phosphoryl]oxy}-1-[(hexadecanoyloxy)methyl]ethyl (9Z)-octadec-9-enoate, CALCIUM ION, afTMEM16 lipid scramblase
Authors:Falzone, M.E, Accardi, A.
Deposit date:2021-08-23
Release date:2022-05-18
Last modified:2024-06-05
Method:ELECTRON MICROSCOPY (2.28 Å)
Cite:TMEM16 scramblases thin the membrane to enable lipid scrambling.
Nat Commun, 13, 2022
6JBJ
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BU of 6jbj by Molmil
Cryo-EM structure of human lysosomal cobalamin exporter ABCD4
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, ATP-binding cassette sub-family D member 4
Authors:Xu, D, Feng, Z, Hou, W.T, Jiang, Y.L, Wang, L, Sun, L.F, Zhou, C.Z, Chen, Y.
Deposit date:2019-01-25
Release date:2019-09-11
Last modified:2024-03-27
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:Cryo-EM structure of human lysosomal cobalamin exporter ABCD4.
Cell Res., 29, 2019
5REQ
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BU of 5req by Molmil
Methylmalonyl-COA MUTASE, Y89F Mutant, substrate complex
Descriptor: COBALAMIN, GLYCEROL, METHYLMALONYL(CARBADETHIA)-COENZYME A, ...
Authors:Evans, P.R, Thomae, N.H.
Deposit date:1998-08-03
Release date:1998-08-12
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Stabilization of radical intermediates by an active-site tyrosine residue in methylmalonyl-CoA mutase.
Biochemistry, 37, 1998
6JBW
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BU of 6jbw by Molmil
Structure of Tps1/UDP complex
Descriptor: Trehalose-6-phosphate synthase, URIDINE-5'-DIPHOSPHATE
Authors:Wang, S, Zhao, Y, Wang, D, Liu, J.
Deposit date:2019-01-26
Release date:2019-12-04
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.65 Å)
Cite:Crystal structures of Magnaporthe oryzae trehalose-6-phosphate synthase (MoTps1) suggest a model for catalytic process of Tps1.
Biochem.J., 476, 2019
6JMG
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BU of 6jmg by Molmil
Crystal structure of xRbj
Descriptor: DnaJ homolog subfamily C member 27-A, GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION
Authors:Gao, Z.R, Qi, J.X.
Deposit date:2019-03-09
Release date:2020-03-11
Last modified:2024-03-27
Method:X-RAY DIFFRACTION (2.701 Å)
Cite:Crystal structure of Rbj
To Be Published

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