6JOL

Crystal structure of PDGFRA in complex with imatinib by co-crystallization

Summary for 6JOL

• Entry DOI: 10.2210/pdb6jol/pdb
• Descriptor: Platelet-derived growth factor receptor alpha, 4-(4-METHYL-PIPERAZIN-1-YLMETHYL)-N-[4-METHYL-3-(4-PYRIDIN-3-YL-PYRIMIDIN-2-YLAMINO)-PHENYL]-BENZAMIDE (3 entities in total)
• Functional Keywords: pdgfra, inhibitor, imatinib, oncoprotein
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 1
• Total formula weight: 41082.33

Authors

Liang, L.,Yan, X.E.,Yun, C.H. (deposition date: 2019-03-22, release date: 2020-03-25, Last modification date: 2023-11-22)

• Primary citation: Liang, L.,Yan, X.E.; Crystal structure of PDGFRA in complex with imatinib by co-crystallization; To Be Published,

Experimental method

X-RAY DIFFRACTION (1.9 Å)