6JQN

Structure of PaaZ, a bifunctional enzyme in complex with NADP+ and OCoA

Summary for 6JQN

Entry DOI	10.2210/pdb6jqn/pdb
EMDB information	9873 9875
Descriptor	Bifunctional protein PaaZ, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, OCTANOYL-COENZYME A (3 entities in total)
Functional Keywords	substrate channeling, bi-functional enzyme, hydrolase, dehydrogenase
Biological source	Escherichia coli K-12
Total number of polymer chains	6
Total formula weight	453639.16
Authors	Gakher, L.,Vinothkumar, K.R.,Katagihallimath, N.,Sowdhamini, R.,Sathyanarayanan, N.,Cannone, G. (deposition date: 2019-03-31, release date: 2019-09-11, Last modification date: 2024-03-27)
Primary citation	Sathyanarayanan, N.,Cannone, G.,Gakhar, L.,Katagihallimath, N.,Sowdhamini, R.,Ramaswamy, S.,Vinothkumar, K.R. Molecular basis for metabolite channeling in a ring opening enzyme of the phenylacetate degradation pathway. Nat Commun, 10:4127-4127, 2019 Cited by PubMed: 31511507 DOI: 10.1038/s41467-019-11931-1 PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (3.1 Å)

Structure validation