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6A45
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BU of 6a45 by Molmil
Structure of mouse TREX2
Descriptor: PHOSPHATE ION, Three prime repair exonuclease 2
Authors:Hsiao, Y.Y.
Deposit date:2018-06-19
Release date:2018-11-07
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (1.904 Å)
Cite:Structural insights into the duplex DNA processing of TREX2
Nucleic Acids Res., 46, 2018
6OZX
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BU of 6ozx by Molmil
Wild type GapR crystal structure 1 from C. crescentus
Descriptor: UPF0335 protein CC_3319
Authors:Tarry, M, Harmel, C, Taylor, J.A, Marczynski, G.T, Schmeing, T.M.
Deposit date:2019-05-16
Release date:2019-11-27
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (1.851 Å)
Cite:Structures of GapR reveal a central channel which could accommodate B-DNA.
Sci Rep, 9, 2019
5FHD
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BU of 5fhd by Molmil
Structure of Bacteroides sp Pif1 complexed with tailed dsDNA resulting in ssDNA bound complex
Descriptor: ADENOSINE-5'-DIPHOSPHATE, DNA (5'-D(*TP*TP*TP*TP*TP*TP*TP*CP*CP*GP*GP*GP*GP*CP*CP*GP*CP*GP*C)-3'), MAGNESIUM ION, ...
Authors:Zhou, X, Ren, W, Bharath, S.R, Song, H.
Deposit date:2015-12-22
Release date:2016-03-30
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural and Functional Insights into the Unwinding Mechanism of Bacteroides sp Pif1
Cell Rep, 14, 2016
6M5T
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BU of 6m5t by Molmil
The coordinate of the nuclease domain of the apo terminase complex
Descriptor: Tripartite terminase subunit 3
Authors:Yang, Y.X, Yang, P, Wang, N, Chen, Z.H, Zhou, Z.H, Rao, Z.H, Wang, X.X.
Deposit date:2020-03-11
Release date:2020-10-28
Last modified:2023-11-29
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:Architecture of the herpesvirus genome-packaging complex and implications for DNA translocation.
Protein Cell, 11, 2020
6OZY
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BU of 6ozy by Molmil
Wild type GapR crystal structure 2 from C. crescentus
Descriptor: CADMIUM ION, UPF0335 protein CC_3319
Authors:Tarry, M, Harmel, C, Taylor, J.A, Marczynski, G.T, Schmeing, T.M.
Deposit date:2019-05-16
Release date:2019-11-27
Last modified:2024-05-22
Method:X-RAY DIFFRACTION (2.014 Å)
Cite:Structures of GapR reveal a central channel which could accommodate B-DNA.
Sci Rep, 9, 2019
3FLD
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BU of 3fld by Molmil
Crystal structure of the trai c-terminal domain
Descriptor: Protein traI, SULFATE ION
Authors:Guogas, L.M, Kennedy, S.A, Redinbo, M.R.
Deposit date:2008-12-18
Release date:2009-02-10
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:A novel fold in the TraI relaxase-helicase c-terminal domain is essential for conjugative DNA transfer.
J.Mol.Biol., 386, 2009
6APY
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BU of 6apy by Molmil
Scabin (W128Y) toxin from Streptomyces scabies
Descriptor: Scabin
Authors:Lyons, B, Lidster, T, Merrill, A.R.
Deposit date:2017-08-18
Release date:2017-12-20
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Characterization of the catalytic signature of Scabin toxin, a DNA-targeting ADP-ribosyltransferase.
Biochem. J., 475, 2018
8OVW
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BU of 8ovw by Molmil
Cryo-EM structure of CBF1-CCAN bound topologically to centromeric DNA
Descriptor: C0N3 DNA, Centromere-binding protein 1, Inner kinetochore subunit AME1, ...
Authors:Dendooven, T.D, Zhang, Z, Yang, J, McLaughlin, S, Schwabb, J, Scheres, S, Yatskevich, S, Barford, D.
Deposit date:2023-04-26
Release date:2023-08-09
Last modified:2024-07-24
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:Cryo-EM structure of the complete inner kinetochore of the budding yeast point centromere.
Sci Adv, 9, 2023
5O7H
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BU of 5o7h by Molmil
Structure of the Cascade-I-Fv complex from Shewanella putrefaciens
Descriptor: CRISPR-associated protein, Csy4 family, Cas5fv, ...
Authors:Pausch, P, Altegoer, F, Bange, G.
Deposit date:2017-06-08
Release date:2017-08-16
Last modified:2017-08-30
Method:X-RAY DIFFRACTION (3 Å)
Cite:Structural Variation of Type I-F CRISPR RNA Guided DNA Surveillance.
Mol. Cell, 67, 2017
8WT7
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BU of 8wt7 by Molmil
Cryo-EM structure of the IS621 recombinase in complex with bridge RNA, donor DNA, and target DNA in the pre-strand exchange locked state
Descriptor: IS621 transposase, MAGNESIUM ION, bridge RNA, ...
Authors:Hiraizumi, M, Yamashita, K, Nishimasu, H.
Deposit date:2023-10-18
Release date:2024-06-26
Last modified:2024-07-17
Method:ELECTRON MICROSCOPY (2.7 Å)
Cite:Structural mechanism of bridge RNA-guided recombination.
Nature, 630, 2024
8WT6
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BU of 8wt6 by Molmil
Cryo-EM structure of the IS621 recombinase in complex with bridge RNA, donor DNA, and target DNA in the pre-strand exchange state
Descriptor: IS621 transposase, MAGNESIUM ION, bridge RNA, ...
Authors:Hiraizumi, M, Yamashita, K, Nishimasu, H.
Deposit date:2023-10-18
Release date:2024-06-26
Last modified:2024-07-17
Method:ELECTRON MICROSCOPY (2.5 Å)
Cite:Structural mechanism of bridge RNA-guided recombination.
Nature, 630, 2024
8YEW
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BU of 8yew by Molmil
TRIP4 ASCH domain in unliganded form
Descriptor: Activating signal cointegrator 1
Authors:Ding, J, Yang, H, Hu, C.
Deposit date:2024-02-23
Release date:2024-06-26
Last modified:2024-08-28
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Biochemical and structural characterization of the DNA-binding properties of human TRIP4 ASCH domain reveals insights into its functional role.
Structure, 32, 2024
8FVX
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BU of 8fvx by Molmil
Histone from Bdellovibrio bacteriovorus
Descriptor: CBFD_NFYB_HMF domain-containing protein
Authors:Laursen, S.P, Luger, K.
Deposit date:2023-01-19
Release date:2023-08-30
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Histones with an unconventional DNA-binding mode in vitro are major chromatin constituents in the bacterium Bdellovibrio bacteriovorus.
Nat Microbiol, 8, 2023
3BI7
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BU of 3bi7 by Molmil
Crystal structure of the SRA domain of E3 ubiquitin-protein ligase UHRF1
Descriptor: 1,2-ETHANEDIOL, E3 ubiquitin-protein ligase UHRF1, SULFATE ION, ...
Authors:Walker, J.R, Avvakumov, G.V, Xue, S, Li, Y, Weigelt, J, Arrowsmith, C.H, Edwards, A.M, Bochkarev, A, Dhe-Paganon, S, Structural Genomics Consortium (SGC)
Deposit date:2007-11-30
Release date:2007-12-18
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Structural basis for recognition of hemi-methylated DNA by the SRA domain of human UHRF1.
Nature, 455, 2008
1N1J
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BU of 1n1j by Molmil
Crystal structure of the NF-YB/NF-YC histone pair
Descriptor: NF-YB, NF-YC
Authors:Romier, C, Cocchiarella, F, Mantovani, R, Moras, D.
Deposit date:2002-10-18
Release date:2003-02-18
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (1.67 Å)
Cite:The NF-YB/NF-YC structure gives insight into DNA binding and transcription regulation by CCAAT factor NF-Y
J.Biol.Chem., 278, 2003
5XH7
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BU of 5xh7 by Molmil
Crystal structure of the Acidaminococcus sp. BV3L6 Cpf1 RR variant in complex with crRNA and target DNA (TCCA PAM)
Descriptor: 1,2-ETHANEDIOL, CHLORIDE ION, CRISPR-associated endonuclease Cpf1, ...
Authors:Nishimasu, H, Yamano, T, Ishitani, R, Nureki, O.
Deposit date:2017-04-19
Release date:2017-06-14
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural Basis for the Altered PAM Recognition by Engineered CRISPR-Cpf1
Mol. Cell, 67, 2017
5GKJ
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BU of 5gkj by Molmil
Structure of EndoMS in apo form
Descriptor: Endonuclease EndoMS
Authors:Nakae, S, Hijikata, A, Tsuji, T, Yonezawa, K, Kouyama, K, Mayanagi, K, Ishino, S, Ishino, Y, Shirai, T.
Deposit date:2016-07-04
Release date:2016-11-02
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Structure of the EndoMS-DNA Complex as Mismatch Restriction Endonuclease
Structure, 24, 2016
3ISP
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BU of 3isp by Molmil
Crystal structure of ArgP from Mycobacterium tuberculosis
Descriptor: HTH-type transcriptional regulator Rv1985c/MT2039
Authors:Zhou, X, Lou, Z, Sheng, F, Bartlam, M, Wang, H, Rao, Z.
Deposit date:2009-08-27
Release date:2010-02-16
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Crystal Structure of ArgP from Mycobacterium tuberculosis Confirms Two Distinct Conformations of Full-length LysR Transcriptional Regulators and Reveals Its Function in DNA Binding and Transcriptional Regulation.
J.Mol.Biol., 2009
7KZR
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BU of 7kzr by Molmil
Structure of the human Fanconi Anaemia Core-UBE2T-ID complex
Descriptor: E3 ubiquitin-protein ligase FANCL, Fanconi anemia core complex-associated protein 100, Fanconi anemia core complex-associated protein 20, ...
Authors:Wang, S.L, Pavletich, N.P.
Deposit date:2020-12-10
Release date:2021-03-10
Last modified:2024-03-06
Method:ELECTRON MICROSCOPY (4.4 Å)
Cite:Structure of the FA core ubiquitin ligase closing the ID clamp on DNA.
Nat.Struct.Mol.Biol., 28, 2021
7KZQ
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BU of 7kzq by Molmil
Structure of the human Fanconi anaemia Core-ID complex
Descriptor: E3 ubiquitin-protein ligase FANCL, Fanconi anemia core complex-associated protein 100, Fanconi anemia core complex-associated protein 20, ...
Authors:Wang, S.L, Pavletich, N.P.
Deposit date:2020-12-10
Release date:2021-03-10
Last modified:2024-03-06
Method:ELECTRON MICROSCOPY (4.3 Å)
Cite:Structure of the FA core ubiquitin ligase closing the ID clamp on DNA.
Nat.Struct.Mol.Biol., 28, 2021
1RIY
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BU of 1riy by Molmil
HU mutant V42I from Thermotoga maritima
Descriptor: Hu DNA-binding protein
Authors:Kavounis, C, Petratos, K, Tucker, P, Vorgias, C.E.
Deposit date:2003-11-18
Release date:2004-12-07
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:The structure of the DNA binding protein HU Thermotoga maritima with a single conservative substitution (V42I) that confers significant destabilisation
To be Published
6WAA
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BU of 6waa by Molmil
K. pneumoniae Topoisomerase IV (ParE-ParC) in complex with DNA and compound 34 (7-[(1S,5R)-1-amino-3-azabicyclo[3.1.0]hexan-3-yl]-4-(aminomethyl)-1-cyclopropyl-3,6-difluoro-8-methylquinolin-2(1H)-one)
Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, 7-[(1S,5R)-1-amino-3-azabicyclo[3.1.0]hexan-3-yl]-4-(aminomethyl)-1-cyclopropyl-3,6-difluoro-8-methylquinolin-2(1H)-one, CHLORIDE ION, ...
Authors:Noeske, J, Shu, W, Bellamacina, C.
Deposit date:2020-03-24
Release date:2020-07-15
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Topoisomerase Inhibitors Addressing Fluoroquinolone Resistance in Gram-Negative Bacteria.
J.Med.Chem., 63, 2020
6W10
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BU of 6w10 by Molmil
Structure of mouse TREX1 with E198K disease-associated mutation
Descriptor: Three-prime repair exonuclease 1
Authors:Zhou, W, Mohr, L, Maciejowski, J, Kranzusch, P.J.
Deposit date:2020-03-03
Release date:2021-02-17
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.80003381 Å)
Cite:cGAS phase separation inhibits TREX1-mediated DNA degradation and enhances cytosolic DNA sensing.
Mol.Cell, 81, 2021
2BNK
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BU of 2bnk by Molmil
The structure of phage phi29 replication organizer protein p16.7
Descriptor: EARLY PROTEIN GP16.7
Authors:Albert, A, Asensio, J.L, Munoz-Espin, D, Gonzalez, C, Hermoso, J.A, Villar, L, Jimenez-Barbero, J, Salas, M, Meijer, W.J.J.
Deposit date:2005-03-28
Release date:2005-04-05
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Structure of the Functional Domain of {Varphi}29 Replication Organizer: Insights Into Oligomerization and DNA Binding.
J.Biol.Chem., 280, 2005
6WG4
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BU of 6wg4 by Molmil
Crystal structure of human SMC1-SMC3 hinge domain heterodimer in south-open conformation
Descriptor: Structural maintenance of chromosomes protein, Structural maintenance of chromosomes protein 3
Authors:Shi, Z.B, Yu, H.
Deposit date:2020-04-04
Release date:2020-05-20
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.31 Å)
Cite:Cryo-EM structure of the human cohesin-NIPBL-DNA complex.
Science, 368, 2020

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