8WT6
Cryo-EM structure of the IS621 recombinase in complex with bridge RNA, donor DNA, and target DNA in the pre-strand exchange state
Summary for 8WT6
Entry DOI | 10.2210/pdb8wt6/pdb |
EMDB information | 37827 |
Descriptor | IS621 transposase, bridge RNA, target DNA, ... (8 entities in total) |
Functional Keywords | holliday junction, rna dependent recombinase, recombination-dna-rna complex, recombination/dna/rna |
Biological source | Escherichia coli More |
Total number of polymer chains | 10 |
Total formula weight | 312918.34 |
Authors | Hiraizumi, M.,Yamashita, K.,Nishimasu, H. (deposition date: 2023-10-18, release date: 2024-06-26, Last modification date: 2024-07-17) |
Primary citation | Hiraizumi, M.,Perry, N.T.,Durrant, M.G.,Soma, T.,Nagahata, N.,Okazaki, S.,Athukoralage, J.S.,Isayama, Y.,Pai, J.J.,Pawluk, A.,Konermann, S.,Yamashita, K.,Hsu, P.D.,Nishimasu, H. Structural mechanism of bridge RNA-guided recombination. Nature, 630:994-1002, 2024 Cited by PubMed: 38926616DOI: 10.1038/s41586-024-07570-2 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (2.5 Å) |
Structure validation
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