5XH7

Crystal structure of the Acidaminococcus sp. BV3L6 Cpf1 RR variant in complex with crRNA and target DNA (TCCA PAM)

Summary for 5XH7

• Entry DOI: 10.2210/pdb5xh7/pdb
• Related: 5XH6
• Descriptor: CRISPR-associated endonuclease Cpf1, crRNA, Target DNA strand, ... (8 entities in total)
• Functional Keywords: nuclease, hydrolase-rna-dna complex, hydrolase/rna/dna
• Biological source: Acidaminococcus sp. (strain BV3L6); More
• Total number of polymer chains: 4
• Total formula weight: 180139.67

Authors

Nishimasu, H.,Yamano, T.,Ishitani, R.,Nureki, O. (deposition date: 2017-04-19, release date: 2017-06-14, Last modification date: 2023-11-22)

• Primary citation: Nishimasu, H.,Yamano, T.,Gao, L.,Zhang, F.,Ishitani, R.,Nureki, O.; Structural Basis for the Altered PAM Recognition by Engineered CRISPR-Cpf1; Mol. Cell, 67:139-147.e2, 2017; PubMed: 28595896; DOI: 10.1016/j.molcel.2017.04.019

Experimental method