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3OVN
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Fragment-based approach to the design of ligands targeting a novel site on HIV-1 integrase
Descriptor: 1-methyl-3-(thiophen-2-yl)-1H-pyrazol-5-amine, CADMIUM ION, POL polyprotein, ...
Authors:Wielens, J, Chalmers, D.K, Headey, S.J, Deadman, J.J, Rhodes, D.K, Parker, M.W, Scanlon, M.J.
Deposit date:2010-09-16
Release date:2011-03-09
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Fragment-based design of ligands targeting a novel site on the integrase enzyme of human immunodeficiency virus 1
Chemmedchem, 6, 2011
6RZ8
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BU of 6rz8 by Molmil
Crystal structure of the human cysteinyl leukotriene receptor 2 in complex with ONO-2080365
Descriptor: (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, (2~{S})-8-[[4-[4-[2,3-bis(fluoranyl)phenoxy]butoxy]-2-fluoranyl-phenyl]carbonylamino]-4-(4-oxidanyl-4-oxidanylidene-but yl)-2,3-dihydro-1,4-benzoxazine-2-carboxylic acid, Cysteinyl leukotriene receptor 2,Soluble cytochrome b562,Cysteinyl leukotriene receptor 2, ...
Authors:Gusach, A, Luginina, A, Marin, E, Brouillette, R.L, Besserer-Offroy, E, Longpre, J.M, Ishchenko, A, Popov, P, Fujimoto, T, Maruyama, T, Stauch, B, Ergasheva, M, Romanovskaya, D, Stepko, A, Kovalev, K, Shevtsov, M, Gordeliy, V, Han, G.W, Sarret, P, Katritch, V, Borshchevskiy, V, Mishin, A, Cherezov, V.
Deposit date:2019-06-12
Release date:2019-12-11
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Structural basis of ligand selectivity and disease mutations in cysteinyl leukotriene receptors.
Nat Commun, 10, 2019
1V38
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BU of 1v38 by Molmil
Solution structure of the Sterile Alpha Motif (SAM) domain of mouse SAMSN1
Descriptor: SAM-domain protein SAMSN-1
Authors:Goroncy, A, Kigawa, T, Koshiba, S, Kobayashi, N, Tochio, N, Inoue, M, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2003-10-29
Release date:2004-04-29
Last modified:2024-05-29
Method:SOLUTION NMR
Cite:Solution structure of the Sterile Alpha Motif (SAM) domain of mouse SAMSN1
To be Published
6X2M
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BU of 6x2m by Molmil
Crystal Structure of unliganded CRM1-Ran-RanBP1
Descriptor: Exportin-1, GLYCEROL, GTP-binding nuclear protein Ran, ...
Authors:Baumhardt, J.M.
Deposit date:2020-05-20
Release date:2020-07-01
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.351 Å)
Cite:Recognition of nuclear export signals by CRM1 carrying the oncogenic E571K mutation.
Mol.Biol.Cell, 31, 2020
1V5Q
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BU of 1v5q by Molmil
Solution Structure of the PDZ Domain from Mouse Glutamate Receptor Interacting Protein 1A-L (GRIP1) Homolog
Descriptor: Glutamate Receptor Interacting Protein 1A-L Homolog
Authors:Sato, M, Tochio, N, Koshiba, S, Inoue, M, Kigawa, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2003-11-25
Release date:2004-05-25
Last modified:2023-12-27
Method:SOLUTION NMR
Cite:Solution Structure of the PDZ Domain from Mouse Glutamate Receptor Interacting Protein 1A-L (GRIP1) Homolog
To be Published
1V6F
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BU of 1v6f by Molmil
Solution Structure of Glia Maturation Factor-beta from Mus Musculus
Descriptor: glia maturation factor, beta
Authors:Goroncy, A.K, Kigawa, T, Koshiba, S, Tomizawa, T, Kobayashi, N, Tochio, N, Inoue, M, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2003-11-29
Release date:2004-05-29
Last modified:2023-12-27
Method:SOLUTION NMR
Cite:NMR solution structures of actin depolymerizing factor homology domains.
Protein Sci., 18, 2009
8AUU
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BU of 8auu by Molmil
Human Aldose Reductase Mutant A299G in Complex with a Ligand with an IDD Structure ({5-fluoro-2-[(3-nitrobenzyl)carbamoyl]phenoxy}acetic acid)
Descriptor: Aldo-keto reductase family 1 member B1, CITRIC ACID, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ...
Authors:Hubert, L.-S, Heine, A, Klebe, G.
Deposit date:2022-08-25
Release date:2023-09-06
Method:X-RAY DIFFRACTION (0.95 Å)
Cite:Human Aldose Reductase Mutant A299G in Complex with a Ligand with an IDD Structure ({5-fluoro-2-[(3-nitrobenzyl)carbamoyl]phenoxy}acetic acid)
To Be Published
1V31
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BU of 1v31 by Molmil
Solution structure of the SWIB/MDM2 domain of the hypothetical protein At5g14170 from Arabidopsis thaliana
Descriptor: hypothetical protein RAFL11-05-P19
Authors:Yoneyama, M, Tochio, N, Koshiba, S, Inoue, M, Kigawa, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2003-10-21
Release date:2004-04-21
Last modified:2023-12-27
Method:SOLUTION NMR
Cite:Solution structure of the SWIB/MDM2 domain of the hypothetical protein At5g14170 from Arabidopsis thaliana
To be Published
1V5U
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Solution Structure of the C-terminal Pleckstrin Homology Domain of Sbf1 from Mouse
Descriptor: SET binding factor 1
Authors:Li, H, Koshiba, S, Inoue, M, Kigawa, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2003-11-25
Release date:2004-05-25
Last modified:2023-12-27
Method:SOLUTION NMR
Cite:Solution Structure of the C-terminal Pleckstrin Homology Domain of Sbf1 from Mouse
To be Published
6X2O
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BU of 6x2o by Molmil
Crystal Structure of unliganded CRM1(E571K)-Ran-RanBP1
Descriptor: Exportin-1, GTP-binding nuclear protein Ran, MAGNESIUM ION, ...
Authors:Baumhardt, J.M.
Deposit date:2020-05-20
Release date:2020-07-01
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.551 Å)
Cite:Recognition of nuclear export signals by CRM1 carrying the oncogenic E571K mutation.
Mol.Biol.Cell, 31, 2020
8DSB
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BU of 8dsb by Molmil
Lambda Bacteriophage Orf63
Descriptor: Xis (Excision72)
Authors:Donaldson, L.W.
Deposit date:2022-07-22
Release date:2023-07-26
Last modified:2024-05-01
Method:SOLUTION NMR
Cite:Bad Phages in Good Bacteria: Role of the Mysterious orf63 of lambda and Shiga Toxin-Converting Phi 24 B Bacteriophages.
Front Microbiol, 8, 2017
1V65
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BU of 1v65 by Molmil
Solution structure of the Kruppel-associated box (KRAB) domain
Descriptor: RIKEN cDNA 2610044O15
Authors:Saito, K, Koshiba, S, Inoue, M, Kigawa, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2003-11-27
Release date:2004-06-01
Last modified:2023-12-27
Method:SOLUTION NMR
Cite:Solution structure of the Kruppel-associated box (KRAB) domain
To be Published
1V9V
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BU of 1v9v by Molmil
Solution structure of putative domain of human KIAA0561 protein
Descriptor: KIAA0561 protein
Authors:Tochio, N, Koshiba, S, Inoue, M, Kigawa, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2004-02-03
Release date:2005-03-01
Last modified:2023-12-27
Method:SOLUTION NMR
Cite:Solution structure of putative domain of human KIAA0561 protein
To be Published
1UL4
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BU of 1ul4 by Molmil
Solution structure of the DNA-binding domain of squamosa promoter binding protein-like 4
Descriptor: ZINC ION, squamosa promoter binding protein-like 4
Authors:Yamasaki, K, Inoue, M, Kigawa, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2003-09-09
Release date:2004-03-09
Last modified:2023-12-27
Method:SOLUTION NMR
Cite:A novel zinc-binding motif revealed by solution structures of DNA-binding domains of Arabidopsis SBP-family transcription factors.
J.Mol.Biol., 337, 2004
5FZ7
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BU of 5fz7 by Molmil
Crystal structure of the catalytic domain of human JARID1B in complex with Maybridge fragment ethyl 2-amino-4-thiophen-2-ylthiophene-3- carboxylate (N06131b) (ligand modelled based on PANDDA event map, SGC - Diamond I04-1 fragment screening)
Descriptor: 1,2-ETHANEDIOL, CHLORIDE ION, DIMETHYL SULFOXIDE, ...
Authors:Nowak, R, Krojer, T, Johansson, C, Kupinska, K, Szykowska, A, Pearce, N, Talon, R, Collins, P, Gileadi, C, Strain-Damerell, C, Burgess-Brown, N.A, Arrowsmith, C.H, Bountra, C, Edwards, A.M, von Delft, F, Brennan, P.E, Oppermann, U.
Deposit date:2016-03-11
Release date:2016-03-23
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Crystal Structure of the Catalytic Domain of Human Jarid1B in Complex with Maybridge Fragment Ethyl 2-Amino-4-Thiophen-2-Ylthiophene-3-Carboxylate (N06131B) (Ligand Modelled Based on Pandda Event Map, Sgc - Diamond I04-1 Fragment Screening)
To be Published
1V60
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BU of 1v60 by Molmil
Solution structure of BolA1 protein from Mus musculus
Descriptor: RIKEN cDNA 1810037G04
Authors:Kasai, T, Tomizawa, T, Koshiba, S, Inoue, M, Kigawa, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2003-11-26
Release date:2005-01-18
Last modified:2023-12-27
Method:SOLUTION NMR
Cite:Solution structure of BolA1 protein from Mus musculus
To be Published
1VAE
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BU of 1vae by Molmil
Solution structure of the PDZ domain of mouse Rhophilin-2
Descriptor: rhophilin, Rho GTPase binding protein 2
Authors:Yoneyama, M, Tochio, N, Koshiba, S, Inoue, M, Kigawa, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2004-02-14
Release date:2004-08-14
Last modified:2023-12-27
Method:SOLUTION NMR
Cite:Solution structure of the PDZ domain of mouse Rhophilin-2
To be Published
1UL7
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BU of 1ul7 by Molmil
Solution structure of kinase associated domain 1 of mouse MAP/microtubule affinity-regulating kinase 3
Descriptor: MAP/microtubule affinity-regulating kinase 3
Authors:Tochio, N, Koshiba, S, Kigawa, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2003-09-10
Release date:2004-03-10
Last modified:2023-12-27
Method:SOLUTION NMR
Cite:Solution structure of the kinase-associated domain 1 of mouse microtubule-associated protein/microtubule affinity-regulating kinase 3
Protein Sci., 15, 2006
1ZUO
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BU of 1zuo by Molmil
Structure of Human Ubiquitin-Conjugating Enzyme (UBCi) Involved in Embryo Attachment and Implantation
Descriptor: BETA-MERCAPTOETHANOL, Hypothetical protein LOC92912
Authors:Walker, J.R, Avvakumov, G.V, Cui, H, Newman, E.M, Mackenzie, F, Sundstrom, M, Arrowsmith, C, Edwards, A, Bochkarev, A, Dhe-Paganon, S, Structural Genomics Consortium (SGC)
Deposit date:2005-05-31
Release date:2005-07-05
Last modified:2012-11-28
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:A human ubiquitin conjugating enzyme (E2)-HECT E3 ligase structure-function screen.
Mol Cell Proteomics, 11, 2012
5V4K
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BU of 5v4k by Molmil
Crystal structure of NEDD4 LIR-fused human LC3B_2-119
Descriptor: GLYCEROL, Microtubule-associated proteins 1A/1B light chain 3B,Microtubule-associated proteins 1A/1B light chain 3B,Microtubule-associated proteins 1A/1B light chain 3B, SULFATE ION
Authors:Qiu, Y, Zheng, Y, Schulman, B.
Deposit date:2017-03-09
Release date:2017-05-17
Last modified:2024-05-22
Method:X-RAY DIFFRACTION (2.099 Å)
Cite:Insights into links between autophagy and the ubiquitin system from the structure of LC3B bound to the LIR motif from the E3 ligase NEDD4.
Protein Sci., 26, 2017
1V5S
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BU of 1v5s by Molmil
Solution structure of kinase associated domain 1 of mouse MAP/microtubule affinity-regulating kinase 3
Descriptor: MAP/microtubule affinity-regulating kinase 3
Authors:Tochio, N, Koshiba, S, Inoue, M, Kigawa, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2003-11-25
Release date:2004-05-25
Last modified:2023-12-27
Method:SOLUTION NMR
Cite:Solution structure of kinase associated domain 1 of mouse MAP/microtubule affinity-regulating kinase 3
To be Published
1V6G
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BU of 1v6g by Molmil
Solution Structure of the LIM Domain of the Human Actin Binding LIM Protein 2
Descriptor: Actin Binding LIM Protein 2, ZINC ION
Authors:Miyamoto, K, Tomizawa, T, Koshiba, S, Inoue, M, Kigawa, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2003-11-29
Release date:2004-06-01
Last modified:2023-12-27
Method:SOLUTION NMR
Cite:Solution Structure of the LIM Domain of the Human Actin Binding LIM Protein 2
To be Published
1V85
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BU of 1v85 by Molmil
Sterile alpha motif (SAM) domain of mouse bifunctional apoptosis regulator
Descriptor: similar to ring finger protein 36
Authors:Goroncy, A, Kigawa, T, Koshiba, S, Hayashi, F, Kobayashi, N, Tochio, N, Inoue, M, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2003-12-29
Release date:2005-01-25
Last modified:2023-12-27
Method:SOLUTION NMR
Cite:Sterile alpha motif (SAM) domain of mouse bifunctional apoptosis regulator
To be Published
1V95
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BU of 1v95 by Molmil
Solution Structure of Anticodon Binding Domain from Nuclear Receptor Coactivator 5 (Human KIAA1637 Protein)
Descriptor: Nuclear receptor coactivator 5
Authors:Zhao, C, Kigawa, T, Tochio, N, Koshiba, S, Inoue, M, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2004-01-20
Release date:2004-07-20
Last modified:2023-12-27
Method:SOLUTION NMR
Cite:Solution Structure of Anticodon Binding Domain from Nuclear Receptor Coactivator 5 (Human KIAA1637 Protein)
To be Published
1V2Y
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BU of 1v2y by Molmil
Solution Structure of Mouse Hypothetical Gene (RIKEN cDNA 3300001G02) Product Homologous to Ubiquitin Fold
Descriptor: 3300001G02Rik protein
Authors:Zhao, C, Kigawa, T, Tomizawa, T, Koshiba, S, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2003-10-17
Release date:2004-04-17
Last modified:2023-12-27
Method:SOLUTION NMR
Cite:Solution Structure of Mouse Hypothetical Gene (RIKEN cDNA 3300001G02) Product Homologous to Ubiquitin Fold
To be Published

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