7BFM
Structure of the M198F M298F double mutant of the Streptomyces coelicolor small laccase T1 copper site
Summary for 7BFM
Entry DOI | 10.2210/pdb7bfm/pdb |
Related | 7B2K 7B4Y |
Descriptor | Putative copper oxidase, TETRAETHYLENE GLYCOL, COPPER (II) ION, ... (4 entities in total) |
Functional Keywords | small laccase, oxidoreductase, t1 copper, double mutant, m198f m298f |
Biological source | Streptomyces coelicolor (strain ATCC BAA-471 / A3(2) / M145) |
Total number of polymer chains | 2 |
Total formula weight | 74824.75 |
Authors | Zovo, K.,Majumdar, S.,Lukk, T. (deposition date: 2021-01-04, release date: 2022-01-12, Last modification date: 2024-01-31) |
Primary citation | Zovo, K.,Pupart, H.,Van Wieren, A.,Gillilan, R.E.,Huang, Q.,Majumdar, S.,Lukk, T. Substitution of the Methionine Axial Ligand of the T1 Copper for the Fungal-like Phenylalanine Ligand (M298F) Causes Local Structural Perturbations that Lead to Thermal Instability and Reduced Catalytic Efficiency of the Small Laccase from Streptomyces coelicolor A3(2). Acs Omega, 7:6184-6194, 2022 Cited by PubMed: 35224382DOI: 10.1021/acsomega.1c06668 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2 Å) |
Structure validation
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