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5IXJ
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BU of 5ixj by Molmil
Tryptophan Synthase beta-subunit from Pyrococcus furiosus with L-threonine non-covalently bound in the active site
Descriptor: SODIUM ION, THREONINE, Tryptophan synthase beta chain 1
Authors:Buller, A.R, Herger, M, Arnold, F.H.
Deposit date:2016-03-23
Release date:2016-08-17
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (1.54 Å)
Cite:Synthesis of beta-Branched Tryptophan Analogues Using an Engineered Subunit of Tryptophan Synthase.
J.Am.Chem.Soc., 138, 2016
5DRF
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BU of 5drf by Molmil
Green/cyan WasCFP-pH5.5 at pH 5.5
Descriptor: GLYCEROL, SODIUM ION, WasCFP-pH5.5 at pH 5.5
Authors:Pletnev, V.Z, Pletneva, N.V, Pletnev, S.V.
Deposit date:2015-09-15
Release date:2016-07-27
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (1.14 Å)
Cite:Crystal structure of pH and T dependent green fluorescent protein WasCFP with Trp based chromophore
Russ.J.Bioorganic Chem., 42 (6), 2016
5DQB
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BU of 5dqb by Molmil
Green/cyan WasCFP at pH 8.0
Descriptor: GLYCEROL, SODIUM ION, WasCFP_pH2
Authors:Pletnev, V, Pletneva, N, Pletnev, S.
Deposit date:2015-09-14
Release date:2016-07-27
Last modified:2019-02-20
Method:X-RAY DIFFRACTION (1.25 Å)
Cite:Crystal structure of pH and T dependent green fluorescent protein WasCFP with Trp based chromophore
Russ.J.Bioorganic Chem., 42 (6), 2016
5DQM
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BU of 5dqm by Molmil
Green/cyan WasCFP at pH 2.0
Descriptor: WasCFP_pH2
Authors:Pletnev, V.Z, Pletneva, N.V, Pletnev, S.V.
Deposit date:2015-09-14
Release date:2016-07-27
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (1.3 Å)
Cite:Crystal structure of pH and T dependent green fluorescent protein WasCFP with Trp based chromophore
Russ.J.Bioorganic Chem., 42 (6), 2016
5DRG
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BU of 5drg by Molmil
Green/cyan WasCFP at pH 10.0
Descriptor: GLYCEROL, Green/cyan WasCFP_pH10 at pH 10.0, SODIUM ION
Authors:Pletnev, V.Z, Pletneva, N.V, Pletnev, S.V.
Deposit date:2015-09-15
Release date:2016-07-27
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (1.14 Å)
Cite:Crystal structure of pH and T dependent green fluorescent protein WasCFP with Trp based chromophore
Russ.J.Bioorganic Chem., 42 (6), 2016
1RD5
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BU of 1rd5 by Molmil
Crystal structure of Tryptophan synthase alpha chain homolog BX1: a member of the chemical plant defense system
Descriptor: MALONIC ACID, Tryptophan synthase alpha chain, chloroplast
Authors:Kulik, V, Hartmann, E, Weyand, M, Frey, M, Gierl, A, Niks, D, Dunn, M.F, Schlichting, I.
Deposit date:2003-11-05
Release date:2004-12-28
Last modified:2024-05-22
Method:X-RAY DIFFRACTION (2.02 Å)
Cite:On the structural basis of the catalytic mechanism and the regulation of the alpha subunit of tryptophan synthase from Salmonella typhimurium and BX1 from maize, two evolutionarily related enzymes.
J.Mol.Biol., 352, 2005
1TJR
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BU of 1tjr by Molmil
Crystal structure of wild-type BX1 complexed with a sulfate ion
Descriptor: BX1, SULFATE ION
Authors:Kulik, V, Hartmann, E, Weyand, M, Frey, M, Gierl, A, Niks, D, Dunn, M.F, Schlichting, I.
Deposit date:2004-06-07
Release date:2005-08-30
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:On the structural basis of the catalytic mechanism and the regulation of the alpha subunit of tryptophan synthase from Salmonella typhimurium and BX1 from maize, two evolutionarily related enzymes.
J.Mol.Biol., 352, 2005
2G36
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BU of 2g36 by Molmil
Crystal structure of Tryptophanyl-tRNA synthetase (EC 6.1.1.2) (Tryptophan-tRNA ligase)(TrpRS) (tm0492) from THERMOTOGA MARITIMA at 2.50 A resolution
Descriptor: IRON/SULFUR CLUSTER, TRYPTOPHAN, Tryptophanyl-tRNA synthetase
Authors:Joint Center for Structural Genomics (JCSG)
Deposit date:2006-02-17
Release date:2006-03-28
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structure of a tryptophanyl-tRNA synthetase containing an iron-sulfur cluster.
Acta Crystallogr.,Sect.F, 66, 2010
6QKY
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Tryptophan synthase subunit alpha from Streptococcus pneumoniae with 3D domain swap in the core of TIM barrel
Descriptor: ACETIC ACID, DI(HYDROXYETHYL)ETHER, GLYCEROL, ...
Authors:Michalska, K, Kowiel, M, Bigelow, L, Endres, M, Gilski, M, Jaskolski, M, Joachimiak, A, Center for Structural Genomics of Infectious Diseases (CSGID)
Deposit date:2019-01-30
Release date:2019-03-27
Last modified:2022-03-30
Method:X-RAY DIFFRACTION (2.54 Å)
Cite:3D domain swapping in the TIM barrel of the alpha subunit of Streptococcus pneumoniae tryptophan synthase.
Acta Crystallogr D Struct Biol, 76, 2020
1II4
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BU of 1ii4 by Molmil
CRYSTAL STRUCTURE OF SER252TRP APERT MUTANT FGF RECEPTOR 2 (FGFR2) IN COMPLEX WITH FGF2
Descriptor: FIBROBLAST GROWTH FACTOR RECEPTOR 2, HEPARIN-BINDING GROWTH FACTOR 2
Authors:Ibrahimi, O.A, Eliseenkova, A.V, Plotnikov, A.N, Ornitz, D.M, Mohammadi, M.
Deposit date:2001-04-20
Release date:2001-05-09
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Structural basis for fibroblast growth factor receptor 2 activation in Apert syndrome.
Proc.Natl.Acad.Sci.USA, 98, 2001
7RNQ
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BU of 7rnq by Molmil
Holo structure of engineered TrpB, 2B9-H275E, from Pyrococcus furiosus in the extended-open conformation
Descriptor: PHOSPHATE ION, SODIUM ION, Tryptophan synthase beta chain 1
Authors:Higgins, P.M, Buller, A.R.
Deposit date:2021-07-29
Release date:2022-08-03
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (2.102 Å)
Cite:Substrate multiplexed protein engineering facilitates promiscuous biocatalytic synthesis.
Nat Commun, 13, 2022
8EGZ
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BU of 8egz by Molmil
Engineered tyrosine synthase (TmTyrS1) derived from T. maritima TrpB with Ser bound as the amino-acrylate intermediate
Descriptor: 1,2-ETHANEDIOL, 2-{[(E)-{3-hydroxy-2-methyl-5-[(phosphonooxy)methyl]pyridin-4-yl}methylidene]amino}prop-2-enoic acid, POTASSIUM ION, ...
Authors:Porter, N.J, Almhjell, P.J, Arnold, F.H.
Deposit date:2022-09-13
Release date:2023-10-04
Last modified:2024-08-14
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:The beta-subunit of tryptophan synthase is a latent tyrosine synthase.
Nat.Chem.Biol., 20, 2024
8EH0
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BU of 8eh0 by Molmil
Engineered tyrosine synthase (TmTyrS1) derived from T. maritima TrpB with Ser bound as the amino-acrylate intermediate and complexed with quinoline N-oxide
Descriptor: 1,2-ETHANEDIOL, 1-oxo-1lambda~5~-quinoline, 2-{[(E)-{3-hydroxy-2-methyl-5-[(phosphonooxy)methyl]pyridin-4-yl}methylidene]amino}prop-2-enoic acid, ...
Authors:Porter, N.J, Almhjell, P.J, Arnold, F.H.
Deposit date:2022-09-13
Release date:2023-10-04
Last modified:2024-08-14
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:The beta-subunit of tryptophan synthase is a latent tyrosine synthase.
Nat.Chem.Biol., 20, 2024
8EH1
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BU of 8eh1 by Molmil
Engineered tyrosine synthase (TmTyrS1) derived from T. maritima TrpB with Ser bound as the amino-acrylate intermediate and complexed with 4-hydroxyquinoline
Descriptor: 2-{[(E)-{3-hydroxy-2-methyl-5-[(phosphonooxy)methyl]pyridin-4-yl}methylidene]amino}prop-2-enoic acid, Engineered tyrosine synthase (TmTyrS1), POTASSIUM ION, ...
Authors:Porter, N.J, Almhjell, P.J, Arnold, F.H.
Deposit date:2022-09-13
Release date:2023-10-04
Last modified:2024-08-14
Method:X-RAY DIFFRACTION (2 Å)
Cite:The beta-subunit of tryptophan synthase is a latent tyrosine synthase.
Nat.Chem.Biol., 20, 2024
8EGY
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BU of 8egy by Molmil
Engineered holo tyrosine synthase (TmTyrS1) derived from T. maritima TrpB
Descriptor: 1,2-ETHANEDIOL, PHOSPHATE ION, POTASSIUM ION, ...
Authors:Porter, N.J, Almhjell, P.J, Arnold, F.H.
Deposit date:2022-09-13
Release date:2023-10-04
Last modified:2024-08-14
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:The beta-subunit of tryptophan synthase is a latent tyrosine synthase.
Nat.Chem.Biol., 20, 2024
6MHA
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BU of 6mha by Molmil
dHP1 Chromodomain Y24W variant bound to histone H3 peptide containing trimethyllysine
Descriptor: Heterochromatin protein 1, histone H3 peptide containing trimethyllysine, H3K9me3
Authors:Brustad, E.M, Krone, M.W, Albanese, K.I, Waters, M.L.
Deposit date:2018-09-17
Release date:2019-09-25
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (1.497 Å)
Cite:Thermodynamic consequences of Tyr to Trp mutations in the cation-pi-mediated binding of trimethyllysine by the HP1 chromodomain
Chem Sci, 11, 2020
4IPN
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BU of 4ipn by Molmil
The complex structure of 6-phospho-beta-glucosidase BglA-2 with thiocellobiose-6P from Streptococcus pneumoniae
Descriptor: 6-O-phosphono-alpha-L-idopyranose-(1-4)-4-thio-beta-D-glucopyranose, 6-phospho-beta-glucosidase
Authors:Yu, W.L, Jiang, Y.L, Andreas, P, Cheng, W, Bai, X.H, Ren, Y.M, Thompsonn, J, Zhou, C.Z, Chen, Y.X.
Deposit date:2013-01-10
Release date:2013-04-24
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.411 Å)
Cite:Structural insights into the substrate specificity of a 6-phospho-&[beta]-glucosidase BglA-2 from Streptococcus pneumoniae TIGR4
J.Biol.Chem., 288, 2013
4IPL
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BU of 4ipl by Molmil
The crystal structure of 6-phospho-beta-glucosidase BglA-2 from Streptococcus pneumoniae
Descriptor: 6-phospho-beta-glucosidase, GLYCEROL
Authors:Yu, W.L, Jiang, Y.L, Andreas, P, Cheng, W, Bai, X.H, Ren, Y.M, Thompsonn, J, Zhou, C.Z, Chen, Y.X.
Deposit date:2013-01-10
Release date:2013-04-24
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.004 Å)
Cite:Structural insights into the substrate specificity of a 6-phospho-&[beta]-glucosidase BglA-2 from Streptococcus pneumoniae TIGR4
J.Biol.Chem., 288, 2013
2H6U
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BU of 2h6u by Molmil
Crystal structure of 5-hydroxyisourate hydrolase (formerly known as TRP, transthyretin related protein)
Descriptor: 5-HYDROXYISOURATE HYDROLASE (FORMERLY KNOWN AS TRP, TRANSTHYRETIN RELATED PROTEIN)
Authors:Zanotti, G, Cendron, L, Folli, C, Ramazzina, I, Percudani, R, Berni, R.
Deposit date:2006-06-01
Release date:2006-10-31
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Structure of Zebra fish HIUase: Insights into Evolution of an Enzyme to a Hormone Transporter.
J.Mol.Biol., 363, 2006
2G8Z
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BU of 2g8z by Molmil
Crystal structure of the ternary complex of signalling protein from sheep (SPS-40) with trimer and designed peptide at 2.5A resolution
Descriptor: (TRP)(PRO)(TRP), 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Chitinase-3-like protein 1, ...
Authors:Ethayathulla, A.S, Srivastava, D.B, Kumar, J, Somvanshi, R.K, Sharma, S, Singh, T.P.
Deposit date:2006-03-04
Release date:2006-04-04
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Crystal structure of the ternary complex of signalling protein from sheep (SPS-40) with trimer and designed peptide at 2.5A resolution
To be Published
2H1X
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BU of 2h1x by Molmil
Crystal structure of 5-hydroxyisourate Hydrolase (formerly known as TRP, Transthyretin Related Protein)
Descriptor: 5-hydroxyisourate Hydrolase (formerly known as TRP, Transthyretin Related Protein)
Authors:Zanotti, G, Cendron, L, Folli, C, Ramazzina, I, Percudani, R, Berni, R.
Deposit date:2006-05-17
Release date:2006-10-31
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.98 Å)
Cite:Structure of Zebra fish HIUase: Insights into Evolution of an Enzyme to a Hormone Transporter.
J.Mol.Biol., 363, 2006
1T0W
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BU of 1t0w by Molmil
25 NMR structures of Truncated Hevein of 32 aa (Hevein-32) complex with N,N,N-triacetylglucosamina
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Hevein
Authors:Aboitiz, N, Vila-Perello, M, Groves, P, Asensio, J.L, Andreu, D, Canada, F.J, Jimenez-Barbero, J.
Deposit date:2004-04-13
Release date:2004-09-28
Last modified:2020-07-29
Method:SOLUTION NMR
Cite:NMR and modeling studies of protein-carbohydrate interactions: synthesis, three-dimensional structure, and recognition properties of a minimum hevein domain with binding affinity for chitooligosaccharides
Chembiochem, 5, 2004
1I1Q
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BU of 1i1q by Molmil
STRUCTURE OF THE COOPERATIVE ALLOSTERIC ANTHRANILATE SYNTHASE FROM SALMONELLA TYPHIMURIUM
Descriptor: ANTHRANILATE SYNTHASE COMPONENT I, ANTHRANILATE SYNTHASE COMPONENT II, TRYPTOPHAN
Authors:Morollo, A.A, Eck, M.J.
Deposit date:2001-02-02
Release date:2001-04-18
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structure of the cooperative allosteric anthranilate synthase from Salmonella typhimurium.
Nat.Struct.Biol., 8, 2001
1R4F
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BU of 1r4f by Molmil
Inosine-Adenosine-Guanosine Preferring Nucleoside Hydrolase From Trypanosoma vivax: Trp260Ala Mutant In Complex With 3-Deaza-Adenosine
Descriptor: 3-DEAZA-ADENOSINE, CALCIUM ION, IAG-nucleoside hydrolase
Authors:Versees, W, Loverix, S, Vandemeulebroucke, A, Geerlings, P, Steyaert, J.
Deposit date:2003-10-06
Release date:2004-04-13
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Leaving group activation by aromatic stacking: an alternative to general Acid catalysis.
J.Mol.Biol., 338, 2004
1T8O
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BU of 1t8o by Molmil
CRYSTAL STRUCTURE OF THE P1 TRP BPTI MUTANT- BOVINE CHYMOTRYPSIN COMPLEX
Descriptor: Chymotrypsin A, Pancreatic trypsin inhibitor, SULFATE ION
Authors:Czapinska, H, Helland, R, Otlewski, J, Smalas, A.O.
Deposit date:2004-05-13
Release date:2005-03-08
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Crystal structures of five bovine chymotrypsin complexes with P1 BPTI variants.
J.Mol.Biol., 344, 2004

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