7RNP

Engineered tryptophan synthase b-subunit from Pyrococcus furiosus, PfTrpB2B9_H275E with 4-Cl-Trp non-covalently bound

Summary for 7RNP

Entry DOI	10.2210/pdb7rnp/pdb
Descriptor	Tryptophan synthase beta chain 1, 4-chloro-L-tryptophan, SODIUM ION, ... (4 entities in total)
Functional Keywords	tryptophan synthase, biosynthetic protein
Biological source	Pyrococcus furiosus
Total number of polymer chains	4
Total formula weight	175008.05
Authors	Higgins, P.M.,Buller, A.R. (deposition date: 2021-07-29, release date: 2022-08-03, Last modification date: 2023-11-15)
Primary citation	McDonald, A.D.,Higgins, P.M.,Buller, A.R. Substrate multiplexed protein engineering facilitates promiscuous biocatalytic synthesis. Nat Commun, 13:5242-5242, 2022 Cited by PubMed: 36068220 DOI: 10.1038/s41467-022-32789-w PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.25 Å)

Structure validation