3CEY
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![BU of 3cey by Molmil](/molmil-images/mine/3cey) | Crystal structure of L3MBTL2 | Descriptor: | Lethal(3)malignant brain tumor-like 2 protein | Authors: | Nady, N, Guo, Y, Pan, P, Allali-Hassani, A, Qi, C, Zhu, H, Dong, A, Mackenzie, F, Crombet, L, Loppnau, P, Kozieradzki, I, Vedadi, M, Edwards, A.M, Weigelt, J, Bountra, C, Arrowsmith, C.H, Bochkarev, A, Read, R, Min, J, Structural Genomics Consortium (SGC) | Deposit date: | 2008-02-29 | Release date: | 2008-05-06 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Methylation-state-specific recognition of histones by the MBT repeat protein L3MBTL2. Nucleic Acids Res., 37, 2009
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4GKC
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4FTI
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![BU of 4fti by Molmil](/molmil-images/mine/4fti) | Crystal Structure of the CHK1 | Descriptor: | GLYCEROL, ISOPROPYL ALCOHOL, SULFATE ION, ... | Authors: | Kang, Y.N, Stuckey, J.A, Chang, P, Russell, A.J. | Deposit date: | 2012-06-27 | Release date: | 2012-08-22 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Crystal Structure of the CHK1 To be Published
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4FTR
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![BU of 4ftr by Molmil](/molmil-images/mine/4ftr) | Crystal Structure of the CHK1 | Descriptor: | 2-[3-(3-methoxy-4-nitrophenyl)-11-oxo-10,11-dihydro-5H-dibenzo[b,e][1,4]diazepin-8-yl]-N,N-dimethylacetamide, GLYCEROL, ISOPROPYL ALCOHOL, ... | Authors: | Kang, Y.N, Stuckey, J.A, Chang, P, Russell, A.J. | Deposit date: | 2012-06-27 | Release date: | 2012-08-22 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.25 Å) | Cite: | Crystal Structure of the CHK1 To be Published
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5L90
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![BU of 5l90 by Molmil](/molmil-images/mine/5l90) | |
2RCQ
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![BU of 2rcq by Molmil](/molmil-images/mine/2rcq) | Crystal structure of human apo Cellular Retinol Binding Protein II (CRBP-II) | Descriptor: | L(+)-TARTARIC ACID, Retinol-binding protein II, cellular, ... | Authors: | Monaco, H.L, Capaldi, S, Perduca, M. | Deposit date: | 2007-09-20 | Release date: | 2007-10-02 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (1.2 Å) | Cite: | Crystal structure of human cellular retinol-binding protein II to 1.2 A resolution. Proteins, 70, 2007
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3CTR
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![BU of 3ctr by Molmil](/molmil-images/mine/3ctr) | Crystal structure of the RRM-domain of the poly(A)-specific ribonuclease PARN bound to m7GTP | Descriptor: | 7-METHYL-GUANOSINE-5'-TRIPHOSPHATE, Poly(A)-specific ribonuclease PARN | Authors: | Monecke, T, Schell, S, Dickmanns, A, Ficner, R. | Deposit date: | 2008-04-14 | Release date: | 2008-07-29 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Crystal structure of the RRM domain of poly(A)-specific ribonuclease reveals a novel m(7)G-cap-binding mode. J.Mol.Biol., 382, 2008
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4G1Y
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![BU of 4g1y by Molmil](/molmil-images/mine/4g1y) | Structural basis for the accommodation of bis- and tris-aromatic derivatives in Vitamin D Nuclear Receptor | Descriptor: | (4E,6Z)-7-(3-{[3,4-bis(hydroxymethyl)benzyl]oxy}phenyl)-3-ethylnona-4,6-dien-3-ol, Nuclear receptor coactivator 1, Vitamin D3 receptor A | Authors: | Ciesielski, F, Sato, Y, Moras, D, Rochel, N. | Deposit date: | 2012-07-11 | Release date: | 2012-09-26 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.85 Å) | Cite: | Structural basis for the accommodation of bis- and tris-aromatic derivatives in vitamin d nuclear receptor. J.Med.Chem., 55, 2012
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3D3W
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3D4U
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![BU of 3d4u by Molmil](/molmil-images/mine/3d4u) | Bovine thrombin-activatable fibrinolysis inhibitor (TAFIa) in complex with tick-derived carboxypeptidase inhibitor. | Descriptor: | ACETATE ION, Carboxypeptidase B2, Carboxypeptidase inhibitor, ... | Authors: | Sanglas, L, Valnickova, Z, Arolas, J.L, Pallares, I, Guevara, T, Sola, M, Kristensen, T, Enghild, J.J, Aviles, F.X, Gomis-Ruth, F.X. | Deposit date: | 2008-05-15 | Release date: | 2008-08-19 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Structure of activated thrombin-activatable fibrinolysis inhibitor, a molecular link between coagulation and fibrinolysis. Mol.Cell, 31, 2008
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3CWD
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![BU of 3cwd by Molmil](/molmil-images/mine/3cwd) | Molecular recognition of nitro-fatty acids by PPAR gamma | Descriptor: | (9E,12Z)-10-nitrooctadeca-9,12-dienoic acid, (9Z,12E)-12-nitrooctadeca-9,12-dienoic acid, Peroxisome proliferator-activated receptor gamma, ... | Authors: | Martynowski, D, Li, Y. | Deposit date: | 2008-04-21 | Release date: | 2008-07-08 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Molecular recognition of nitrated fatty acids by PPAR gamma. Nat.Struct.Mol.Biol., 15, 2008
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2RLQ
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![BU of 2rlq by Molmil](/molmil-images/mine/2rlq) | NMR structure of CCP modules 2-3 of complement factor H | Descriptor: | Complement factor H | Authors: | Hocking, H.G, Herbert, A.P, Pangburn, M.K, Kavanagh, D, Barlow, P.N, Uhrin, D. | Deposit date: | 2007-07-29 | Release date: | 2008-02-19 | Last modified: | 2022-03-16 | Method: | SOLUTION NMR | Cite: | Structure of the N-terminal region of complement factor H and conformational implications of disease-linked sequence variations. J.Biol.Chem., 283, 2008
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3D6F
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4FXL
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![BU of 4fxl by Molmil](/molmil-images/mine/4fxl) | Crystal structure of the D76N Beta-2 Microglobulin mutant | Descriptor: | ACETATE ION, Beta-2-microglobulin, DI(HYDROXYETHYL)ETHER, ... | Authors: | Ricagno, S, Bellotti, V, Pepys, M.B, Stoppini, M, Bolognesi, M. | Deposit date: | 2012-07-03 | Release date: | 2012-08-15 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (1.4 Å) | Cite: | Hereditary systemic amyloidosis due to Asp76Asn variant beta-2-microglobulin. N.Engl.J.Med., 366, 2012
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4GD7
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![BU of 4gd7 by Molmil](/molmil-images/mine/4gd7) | Wild-Type Human Thymidylate Synthase with bound Purpurogallin | Descriptor: | 1,2-ETHANEDIOL, 2,3,4,6-tetrahydroxy-5H-benzo[7]annulen-5-one, SULFATE ION, ... | Authors: | Celeste, L.R, Lebioda, L. | Deposit date: | 2012-07-31 | Release date: | 2013-07-31 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (2.29 Å) | Cite: | Oxidation of Cysteine 195 of Huyman Thymidylate Synthase by Purpurogallin To be published, 2012
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3D2W
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![BU of 3d2w by Molmil](/molmil-images/mine/3d2w) | Crystal structure of mouse TDP-43 RRM2 domain in complex with DNA | Descriptor: | DNA (5'-D(*DGP*DTP*DTP*DGP*DAP*DGP*DCP*DGP*DTP*DT)-3'), PHOSPHATE ION, TAR DNA-binding protein 43 | Authors: | Kuo, P.H, Yuan, H.S. | Deposit date: | 2008-05-09 | Release date: | 2009-04-07 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (1.65 Å) | Cite: | Structural insights into TDP-43 in nucleic-acid binding and domain interactions Nucleic Acids Res., 37, 2009
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3D48
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3D57
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![BU of 3d57 by Molmil](/molmil-images/mine/3d57) | TR Variant D355R | Descriptor: | SULFATE ION, Thyroid hormone receptor beta, [4-(4-HYDROXY-3-IODO-PHENOXY)-3,5-DIIODO-PHENYL]-ACETIC ACID | Authors: | Jouravel, N. | Deposit date: | 2008-05-15 | Release date: | 2008-10-14 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Molecular basis for dimer formation of TRbeta variant D355R. Proteins, 75, 2008
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3D5Q
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![BU of 3d5q by Molmil](/molmil-images/mine/3d5q) | Crystal Structure of 11b-HSD1 in Complex with Triazole Inhibitor | Descriptor: | 3-[1-(4-fluorophenyl)cyclopropyl]-4-(1-methylethyl)-5-[4-(trifluoromethoxy)phenyl]-4H-1,2,4-triazole, Corticosteroid 11-beta-dehydrogenase isozyme 1, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | Authors: | Wang, Z, Liu, J, Sudom, A, Walker, N.P.C. | Deposit date: | 2008-05-16 | Release date: | 2008-10-07 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (2.55 Å) | Cite: | Distinctive molecular inhibition mechanisms for selective inhibitors of human 11beta-hydroxysteroid dehydrogenase type 1. Bioorg.Med.Chem., 16, 2008
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4G7W
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4FSR
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![BU of 4fsr by Molmil](/molmil-images/mine/4fsr) | Crystal Structure of the CHK1 | Descriptor: | 6,7-dimethoxy-3-[4-(1H-tetrazol-5-yl)phenyl]-1,4-dihydroindeno[1,2-c]pyrazole, SULFATE ION, Serine/threonine-protein kinase Chk1 | Authors: | Kang, Y.N, Stuckey, J.A, Chang, P, Russell, A.J. | Deposit date: | 2012-06-27 | Release date: | 2012-08-22 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Crystal Structure of the CHK1 To be Published
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2RFE
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![BU of 2rfe by Molmil](/molmil-images/mine/2rfe) | Crystal structure of the complex between the EGFR kinase domain and a Mig6 peptide | Descriptor: | ERBB receptor feedback inhibitor 1, Epidermal growth factor receptor | Authors: | Zhang, X, Pickin, K.A, Bose, R, Jura, N, Cole, P.A, Kuriyan, J. | Deposit date: | 2007-09-28 | Release date: | 2007-12-04 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | Inhibition of the EGF receptor by binding of MIG6 to an activating kinase domain interface. Nature, 450, 2007
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4G9C
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![BU of 4g9c by Molmil](/molmil-images/mine/4g9c) | Human B-Raf Kinase Domain bound to a Type II Pyrazolopyridine Inhibitor | Descriptor: | 3-{[3-(2-cyanopropan-2-yl)benzoyl]amino}-2,6-difluoro-N-(3-methoxy-2H-pyrazolo[3,4-b]pyridin-5-yl)benzamide, Serine/threonine-protein kinase B-raf | Authors: | Voegtli, W.C, Sturgis, H.L. | Deposit date: | 2012-07-23 | Release date: | 2012-11-14 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (3.5 Å) | Cite: | Pyrazolopyridine inhibitors of B-Raf(V600E). Part 4: Rational design and kinase selectivity profile of cell potent type II inhibitors. Bioorg.Med.Chem.Lett., 22, 2012
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2RHP
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![BU of 2rhp by Molmil](/molmil-images/mine/2rhp) | The Thrombospondin-1 Polymorphism Asn700Ser Associated with Cornoary Artery Disease Causes Local and Long-Ranging Changes in Protein Structure | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ... | Authors: | Carlson, C.B, Keck, J.L, Mosher, D.F. | Deposit date: | 2007-10-09 | Release date: | 2008-05-27 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | Influences of the N700S Thrombospondin-1 Polymorphism on Protein Structure and Stability. J.Biol.Chem., 283, 2008
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3CQG
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![BU of 3cqg by Molmil](/molmil-images/mine/3cqg) | Nucleoporin Nup107/Nup133 interaction complex, delta finger mutant | Descriptor: | Nuclear pore complex protein Nup107, Nuclear pore complex protein Nup133 | Authors: | Jeudy, S, Boehmer, T, Berke, I, Schwartz, T.U. | Deposit date: | 2008-04-02 | Release date: | 2008-07-01 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Structural and functional studies of Nup107/Nup133 interaction and its implications for the architecture of the nuclear pore complex. Mol.Cell, 30, 2008
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