Molecular recognition of nitro-fatty acids by PPAR gamma

Summary for 3CWD

DescriptorPeroxisome proliferator-activated receptor gamma, SRC1-2 PEPTIDE, (9E,12Z)-10-nitrooctadeca-9,12-dienoic acid, ... (5 entities in total)
Functional Keywordsppar gamma, nuclear receptor, src1-2 motif, activator, alternative splicing, diabetes mellitus, disease mutation, dna-binding, metal-binding, nucleus, obesity, phosphoprotein, polymorphism, transcription, transcription regulation, zinc, zinc-finger
Biological sourceHomo sapiens (Human)
Cellular locationNucleus P37231
Nucleus (By similarity) Q15788
Total number of polymer chains4
Total molecular weight66847.96
Martynowski, D.,Li, Y. (deposition date: 2008-04-21, release date: 2008-07-08, Last modification date: 2011-07-13)
Primary citation
Li, Y.,Zhang, J.,Schopfer, F.J.,Martynowski, D.,Garcia-Barrio, M.T.,Kovach, A.,Suino-Powell, K.,Baker, P.R.,Freeman, B.A.,Chen, Y.E.,Xu, H.E.
Molecular recognition of nitrated fatty acids by PPAR gamma.
Nat.Struct.Mol.Biol., 15:865-867, 2008
PubMed: 18604218 (PDB entries with the same primary citation)
DOI: 10.1038/nsmb.1447
MImport into Mendeley
Experimental method
NMR Information

Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.302152.6%12.0%8.0%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
Download full validation report