3CTR

Crystal structure of the RRM-domain of the poly(A)-specific ribonuclease PARN bound to m7GTP

Summary for 3CTR

Entry DOI	10.2210/pdb3ctr/pdb
Descriptor	Poly(A)-specific ribonuclease PARN, 7-METHYL-GUANOSINE-5'-TRIPHOSPHATE (3 entities in total)
Functional Keywords	parn, protein-rna-complex, m7g-cap, m7gtp, rna recognition motif, rrm, exonuclease, hydrolase, magnesium, metal-binding, nonsense-mediated mrna decay, nuclease, nucleus, phosphoprotein, rna-binding
Biological source	Homo sapiens (human)
Cellular location	Nucleus : O95453
Total number of polymer chains	1
Total formula weight	12360.39
Authors	Monecke, T.,Schell, S.,Dickmanns, A.,Ficner, R. (deposition date: 2008-04-14, release date: 2008-07-29, Last modification date: 2024-02-21)
Primary citation	Monecke, T.,Schell, S.,Dickmanns, A.,Ficner, R. Crystal structure of the RRM domain of poly(A)-specific ribonuclease reveals a novel m(7)G-cap-binding mode. J.Mol.Biol., 382:827-834, 2008 Cited by PubMed: 18694759 DOI: 10.1016/j.jmb.2008.07.073 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.1 Å)

Structure validation