6TBM
 
 | | Structure of SAGA bound to TBP, including Spt8 and DUB | | Descriptor: | Polyubiquitin-B, SAGA-associated factor 11, Spt20, ... | | Authors: | Papai, G, Frechard, A, Kolesnikova, O, Crucifix, C, Schultz, P, Ben-Shem, A. | | Deposit date: | 2019-11-01 | | Release date: | 2020-02-12 | | Last modified: | 2024-09-25 | | Method: | ELECTRON MICROSCOPY (20 Å) | | Cite: | Structure of SAGA and mechanism of TBP deposition on gene promoters.
Nature, 577, 2020
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6OM7
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3CL6
 | | Crystal structure of Puue Allantoinase | | Descriptor: | Puue allantoinase | | Authors: | Ramazzina, I, Cendron, L, Folli, C, Berni, R, Monteverdi, D, Zanotti, G, Percudani, R. | | Deposit date: | 2008-03-18 | | Release date: | 2008-06-10 | | Last modified: | 2023-11-01 | | Method: | X-RAY DIFFRACTION (1.58 Å) | | Cite: | Logical identification of an allantoinase analog (puuE) recruited from polysaccharide deacetylases
J.Biol.Chem., 283, 2008
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6SKG
 | | Cryo-EM Structure of T. kodakarensis 70S ribosome in TkNat10 deleted strain | | Descriptor: | 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ... | | Authors: | Matzov, D, Sas-Chen, A, Thomas, J.M, Santangelo, T, Meier, J.L, Schwartz, S, Shalev-Benami, M. | | Deposit date: | 2019-08-15 | | Release date: | 2020-07-29 | | Last modified: | 2024-05-22 | | Method: | ELECTRON MICROSCOPY (2.65 Å) | | Cite: | Dynamic RNA acetylation revealed by quantitative cross-evolutionary mapping.
Nature, 583, 2020
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3CFV
 | | Structural basis of the interaction of RbAp46/RbAp48 with histone H4 | | Descriptor: | ARSENIC, Histone H4 peptide, Histone-binding protein RBBP7 | | Authors: | Pei, X.-Y, Murzina, N.V, Zhang, W, McLaughlin, S, Verreault, A, Luisi, B.F, Laue, E.D. | | Deposit date: | 2008-03-04 | | Release date: | 2008-06-10 | | Last modified: | 2024-04-03 | | Method: | X-RAY DIFFRACTION (2.6 Å) | | Cite: | Structural Basis for the Recognition of Histone H4 by the Histone-Chaperone RbAp46.
Structure, 16, 2008
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6T7I
 | | Structure of yeast 80S ribosome stalled on the CGA-CGA inhibitory codon combination. | | Descriptor: | 18S ribosomal RNA, 25S ribosomal RNA, 40S ribosomal protein S0-A, ... | | Authors: | Tesina, P, Buschauer, R, Cheng, J, Berninghausen, O, Becker, R, Beckmann, R. | | Deposit date: | 2019-10-22 | | Release date: | 2019-12-25 | | Last modified: | 2024-05-22 | | Method: | ELECTRON MICROSCOPY (3.2 Å) | | Cite: | Molecular mechanism of translational stalling by inhibitory codon combinations and poly(A) tracts.
Embo J., 39, 2020
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6OFZ
 | | Crystal structure of human WDR5 | | Descriptor: | WD repeat-containing protein 5 | | Authors: | Lorton, B.M, Harijan, R.K, Burgos, E, Bonanno, J.B, Almo, S.C, Shechter, D. | | Deposit date: | 2019-04-01 | | Release date: | 2020-04-01 | | Last modified: | 2023-10-11 | | Method: | X-RAY DIFFRACTION (1.85 Å) | | Cite: | A Binary Arginine Methylation Switch on Histone H3 Arginine 2 Regulates Its Interaction with WDR5.
Biochemistry, 59, 2020
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4D5L
 | | Cryo-EM structures of ribosomal 80S complexes with termination factors and cricket paralysis virus IRES reveal the IRES in the translocated state | | Descriptor: | 18S RRNA 2, 40S RIBOSOMAL PROTEIN ES1, 40S RIBOSOMAL PROTEIN ES10, ... | | Authors: | Muhs, M, Hilal, T, Mielke, T, Skabkin, M.A, Sanbonmatsu, K.Y, Pestova, T.V, Spahn, C.M.T. | | Deposit date: | 2014-11-05 | | Release date: | 2015-02-04 | | Last modified: | 2017-08-23 | | Method: | ELECTRON MICROSCOPY (9 Å) | | Cite: | Cryo-Em of Ribosomal 80S Complexes with Termination Factors Reveals the Translocated Cricket Paralysis Virus Ires.
Mol.Cell, 57, 2015
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6O8Y
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6T9K
 | | SAGA Core module | | Descriptor: | Protein SPT3, SAGA-associated factor 73, Transcription factor SPT20, ... | | Authors: | Wang, H, Cheung, A, Cramer, P. | | Deposit date: | 2019-10-28 | | Release date: | 2020-01-29 | | Last modified: | 2024-05-22 | | Method: | ELECTRON MICROSCOPY (3.3 Å) | | Cite: | Structure of the transcription coactivator SAGA.
Nature, 577, 2020
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6OI2
 | | Crystal structure of human WDR5 in complex with symmetric dimethyl-L-arginine | | Descriptor: | GLYCEROL, N3, N4-DIMETHYLARGININE, ... | | Authors: | Lorton, B.M, Harijan, R.K, Burgos, E, Bonanno, J.B, Almo, S.C, Shechter, D. | | Deposit date: | 2019-04-08 | | Release date: | 2020-04-01 | | Last modified: | 2023-10-11 | | Method: | X-RAY DIFFRACTION (1.68 Å) | | Cite: | A Binary Arginine Methylation Switch on Histone H3 Arginine 2 Regulates Its Interaction with WDR5.
Biochemistry, 59, 2020
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6OLG
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6OY9
 | | Structure of the Rhodopsin-Transducin Complex | | Descriptor: | Gt-alpha/Gi1-alpha chimera, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(T) subunit gamma-T1, ... | | Authors: | Gao, Y, Hu, H, Ramachandran, S, Erickson, J.W, Cerione, R.A, Skiniotis, G. | | Deposit date: | 2019-05-14 | | Release date: | 2019-07-24 | | Last modified: | 2019-12-04 | | Method: | ELECTRON MICROSCOPY (3.9 Å) | | Cite: | Structures of the Rhodopsin-Transducin Complex: Insights into G-Protein Activation.
Mol.Cell, 75, 2019
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6QTV
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6HJY
 | | X-ray structure of a pentameric ligand gated ion channel from Erwinia chrysanthemi (ELIC) Delta8 truncation mutant in complex with nanobody 72 | | Descriptor: | Cys-loop ligand-gated ion channel, nanobody 72 | | Authors: | Spurny, R, Govaerts, C, Evans, G.L, Pardon, E, Steyaert, J, Ulens, C. | | Deposit date: | 2018-09-04 | | Release date: | 2019-10-09 | | Last modified: | 2024-01-17 | | Method: | X-RAY DIFFRACTION (2.78 Å) | | Cite: | A lipid site shapes the agonist response of a pentameric ligand-gated ion channel.
Nat.Chem.Biol., 15, 2019
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6QTQ
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6QTX
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6RLQ
 | | CRYSTAL STRUCTURE OF THE HUMAN PRMT5:MEP50 COMPLEX with JNJ45031882 | | Descriptor: | (1~{S},2~{R},3~{S},5~{R})-3-[2-(2-azanyl-3-bromanyl-quinolin-7-yl)ethyl]-5-(4-azanylpyrrolo[2,3-d]pyrimidin-7-yl)cyclop entane-1,2-diol, Methylosome protein 50, Protein arginine N-methyltransferase 5 | | Authors: | Brown, D.G, Robinson, C.M, Pande, V. | | Deposit date: | 2019-05-02 | | Release date: | 2020-07-15 | | Last modified: | 2024-05-15 | | Method: | X-RAY DIFFRACTION (2.53 Å) | | Cite: | CRYSTAL STRUCTURE OF THE HUMAN PRMT5:MEP50 COMPLEX with JNJ45031882
To Be Published
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6RM3
 | | Evolutionary compaction and adaptation visualized by the structure of the dormant microsporidian ribosome | | Descriptor: | 16S rRNA, 23S rRNA, 5S rRNA, ... | | Authors: | Barandun, J, Hunziker, M, Vossbrinck, C.R, Klinge, S. | | Deposit date: | 2019-05-05 | | Release date: | 2019-07-10 | | Last modified: | 2024-07-10 | | Method: | ELECTRON MICROSCOPY (3.4 Å) | | Cite: | Evolutionary compaction and adaptation visualized by the structure of the dormant microsporidian ribosome.
Nat Microbiol, 4, 2019
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6TLJ
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6JWN
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6TNU
 | | Yeast 80S ribosome in complex with eIF5A and decoding A-site and P-site tRNAs. | | Descriptor: | 18S rRNA, 25S rRNA, 4-{(2R)-2-[(1S,3S,5S)-3,5-dimethyl-2-oxocyclohexyl]-2-hydroxyethyl}piperidine-2,6-dione, ... | | Authors: | Buschauer, R, Cheng, J, Berninghausen, O, Tesina, P, Becker, T, Beckmann, R. | | Deposit date: | 2019-12-10 | | Release date: | 2020-04-22 | | Last modified: | 2020-04-29 | | Method: | ELECTRON MICROSCOPY (3.1 Å) | | Cite: | The Ccr4-Not complex monitors the translating ribosome for codon optimality.
Science, 368, 2020
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6QTO
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6QTW
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6QX9
 | | Structure of a human fully-assembled precatalytic spliceosome (pre-B complex). | | Descriptor: | 116 kDa U5 small nuclear ribonucleoprotein component, AdML pre-mRNA, GUANOSINE-5'-TRIPHOSPHATE, ... | | Authors: | Charenton, C, Wilkinson, M.E, Nagai, K. | | Deposit date: | 2019-03-07 | | Release date: | 2019-04-17 | | Last modified: | 2020-10-07 | | Method: | ELECTRON MICROSCOPY (3.28 Å) | | Cite: | Mechanism of 5' splice site transfer for human spliceosome activation.
Science, 364, 2019
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