7U2K
C6-guano bound Mu Opioid Receptor-Gi Protein Complex
Summary for 7U2K
Entry DOI | 10.2210/pdb7u2k/pdb |
EMDB information | 26313 |
Descriptor | Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Mu-type opioid receptor, ... (5 entities in total) |
Functional Keywords | gpcr, membrane protein |
Biological source | Homo sapiens (human) More |
Total number of polymer chains | 4 |
Total formula weight | 126343.97 |
Authors | Wang, H.,Kobilka, B. (deposition date: 2022-02-24, release date: 2022-12-07, Last modification date: 2023-02-08) |
Primary citation | Faouzi, A.,Wang, H.,Zaidi, S.A.,DiBerto, J.F.,Che, T.,Qu, Q.,Robertson, M.J.,Madasu, M.K.,El Daibani, A.,Varga, B.R.,Zhang, T.,Ruiz, C.,Liu, S.,Xu, J.,Appourchaux, K.,Slocum, S.T.,Eans, S.O.,Cameron, M.D.,Al-Hasani, R.,Pan, Y.X.,Roth, B.L.,McLaughlin, J.P.,Skiniotis, G.,Katritch, V.,Kobilka, B.K.,Majumdar, S. Structure-based design of bitopic ligands for the μ-opioid receptor. Nature, 613:767-774, 2023 Cited by PubMed: 36450356DOI: 10.1038/s41586-022-05588-y PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (3.3 Å) |
Structure validation
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