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7CPV
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BU of 7cpv by Molmil
Cryo-EM structure of 80S ribosome from mouse testis
Descriptor: 40S ribosomal protein S10, 40S ribosomal protein S11, 40S ribosomal protein S13, ...
Authors:Huo, Y.G, He, X, Jiang, T, Qin, Y, Guo, X.J, Sha, J.H.
Deposit date:2020-08-08
Release date:2022-02-02
Last modified:2024-05-29
Method:ELECTRON MICROSCOPY (3.03 Å)
Cite:A male germ-cell-specific ribosome controls male fertility.
Nature, 612, 2022
6XU6
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BU of 6xu6 by Molmil
Drosophila melanogaster Testis 80S ribosome
Descriptor: 18S ribosomal RNA, 28S ribosomal RNA, 2S ribosomal RNA, ...
Authors:Hopes, T, Agapiou, M, Norris, K, McCarthy, C.G.P, OConnell, M.J, Fontana, J, Aspden, J.L.
Deposit date:2020-01-17
Release date:2021-07-28
Last modified:2022-12-21
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:Ribosome heterogeneity in Drosophila melanogaster gonads through paralog-switching.
Nucleic Acids Res., 50, 2022
6XU7
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BU of 6xu7 by Molmil
Drosophila melanogaster Testis polysome ribosome
Descriptor: 18S ribosomal RNA, 28S ribosomal RNA, 2S ribosomal RNA, ...
Authors:Hopes, T, Agapiou, M, Norris, K, McCarthy, C.G.P, OConnell, M.J, Fontana, J, Aspden, J.L.
Deposit date:2020-01-17
Release date:2021-07-28
Last modified:2022-12-21
Method:ELECTRON MICROSCOPY (4.9 Å)
Cite:Ribosome heterogeneity in Drosophila melanogaster gonads through paralog-switching.
Nucleic Acids Res., 50, 2022
3X1T
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BU of 3x1t by Molmil
Crystal structure of nucleosome core particle consisting of mouse testis specific histone variants H2aa and H2ba
Descriptor: CHLORIDE ION, DNA (146-MER), Histone H2A, ...
Authors:Sivaraman, P, Kumarevel, T.S.
Deposit date:2014-11-27
Release date:2015-09-23
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.808 Å)
Cite:Structural and functional analyses of nucleosome complexes with mouse histone variants TH2a and TH2b, involved in reprogramming
Biochem.Biophys.Res.Commun., 464, 2015
5UP5
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BU of 5up5 by Molmil
Solution structure of the de novo mini protein EHEE_rd1_0284
Descriptor: EHEE_rd1_0284
Authors:Houliston, S, Rocklin, G.J, Lemak, A, Carter, L, Chidyausiku, T.M, Baker, D, Arrowsmith, C.H.
Deposit date:2017-02-01
Release date:2017-07-26
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:Global analysis of protein folding using massively parallel design, synthesis, and testing.
Science, 357, 2017
5UOI
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BU of 5uoi by Molmil
Solution structure of the de novo mini protein HHH_rd1_0142
Descriptor: HHH_rd1_0142
Authors:Houliston, S, Rocklin, G.J, Lemak, A, Carter, L, Chidyausiku, T.M, Baker, D, Arrowsmith, C.H.
Deposit date:2017-01-31
Release date:2017-07-26
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:Global analysis of protein folding using massively parallel design, synthesis, and testing.
Science, 357, 2017
5UP1
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BU of 5up1 by Molmil
Solution structure of the de novo mini protein EEHEE_rd3_1049
Descriptor: EEHEE_rd3_1049
Authors:Houliston, S, Rocklin, G.J, Lemak, A, Carter, L, Chidyausiku, T.M, Baker, D, Arrowsmith, C.H.
Deposit date:2017-02-01
Release date:2017-07-26
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:Global analysis of protein folding using massively parallel design, synthesis, and testing.
Science, 357, 2017
5UYO
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BU of 5uyo by Molmil
Solution NMR structure of the de novo mini protein HEEH_rd4_0097
Descriptor: HEEH_rd4_0097
Authors:Lemak, A, Rocklin, G.J, Houliston, S, Carter, L, Chidyausiku, T.M, Baker, D, Arrowsmith, C.H.
Deposit date:2017-02-24
Release date:2017-07-26
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:Global analysis of protein folding using massively parallel design, synthesis, and testing.
Science, 357, 2017
4A60
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BU of 4a60 by Molmil
Crystal structure of human testis-specific fatty acid binding protein 9 (FABP9)
Descriptor: 1,2-ETHANEDIOL, FATTY ACID-BINDING PROTEIN 9 TESTIS LIPID-BINDING PROTEIN, TLBP, ...
Authors:Muniz, J.R.C, Kiyani, W, Shrestha, L, Froese, D.S, Krojer, T, Vollmar, M, Arrowsmith, C.H, Edwards, A.M, Weigelt, J, Bountra, C, von Delft, F, Yue, W.W.
Deposit date:2011-10-31
Release date:2011-11-09
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (1.53 Å)
Cite:The Crystal Structure of the Human Fabp9A
To be Published
5C7L
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BU of 5c7l by Molmil
Structure of human testis-specific glyceraldehyde-3-phosphate dehydrogenase apo form
Descriptor: Glyceraldehyde-3-phosphate dehydrogenase, testis-specific
Authors:Betts, L, Machius, M, Danshina, P, O'Brien, D.
Deposit date:2015-06-24
Release date:2016-03-09
Last modified:2019-12-11
Method:X-RAY DIFFRACTION (1.862 Å)
Cite:Structural analyses to identify selective inhibitors of glyceraldehyde 3-phosphate dehydrogenase-S, a sperm-specific glycolytic enzyme.
Mol. Hum. Reprod., 22, 2016
4FLP
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BU of 4flp by Molmil
Crystal Structure of the first bromodomain of human BRDT in complex with the inhibitor JQ1
Descriptor: (6S)-6-(2-tert-butoxy-2-oxoethyl)-4-(4-chlorophenyl)-2,3,9-trimethyl-6,7-dihydrothieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepin-10-ium, Bromodomain testis-specific protein, POTASSIUM ION
Authors:Filippakopoulos, P, Picaud, S, Qi, J, Felletar, I, Canning, P, Muniz, J, von Delft, F, Bountra, C, Arrowsmith, C.H, Edwards, A, Bradner, J, Knapp, S, Structural Genomics Consortium (SGC)
Deposit date:2012-06-15
Release date:2012-07-11
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.23 Å)
Cite:Small-Molecule Inhibition of BRDT for Male Contraception.
Cell(Cambridge,Mass.), 150, 2012
5C7O
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BU of 5c7o by Molmil
Structure of human testis-specific glyceraldehyde-3-phosphate dehydrogenase holo form with NAD+
Descriptor: Glyceraldehyde-3-phosphate dehydrogenase, testis-specific, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, ...
Authors:Betts, L, Machius, M, Danshina, P, O'Brien, D.
Deposit date:2015-06-24
Release date:2016-03-09
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (1.729 Å)
Cite:Structural analyses to identify selective inhibitors of glyceraldehyde 3-phosphate dehydrogenase-S, a sperm-specific glycolytic enzyme.
Mol. Hum. Reprod., 22, 2016
4KCX
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BU of 4kcx by Molmil
BRDT in complex with Dinaciclib
Descriptor: 3-[({3-ethyl-5-[(2S)-2-(2-hydroxyethyl)piperidin-1-yl]pyrazolo[1,5-a]pyrimidin-7-yl}amino)methyl]-1-hydroxypyridinium, Bromodomain testis-specific protein, CHLORIDE ION
Authors:Martin, M.P, Schonbrunn, E.
Deposit date:2013-04-24
Release date:2013-09-18
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2 Å)
Cite:Cyclin-dependent kinase inhibitor dinaciclib interacts with the acetyl-lysine recognition site of bromodomains.
Acs Chem.Biol., 8, 2013
6YLZ
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BU of 6ylz by Molmil
X-ray structure of the K72I,Y129F,R133L, H199A quadruple mutant of PNP-oxidase from E. coli
Descriptor: FLAVIN MONONUCLEOTIDE, PHOSPHATE ION, Pyridoxine/pyridoxamine 5'-phosphate oxidase, ...
Authors:Battista, T, Sularea, M, Barile, A, Fiorillo, A, Tramonti, A, Ilari, A.
Deposit date:2020-04-07
Release date:2021-04-14
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (1.558 Å)
Cite:Identification and characterization of the pyridoxal 5'-phosphate allosteric site in Escherichia coli pyridoxine 5'-phosphate oxidase.
J.Biol.Chem., 296, 2021
6YMH
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BU of 6ymh by Molmil
X-ray structure of the K72I, Y129F, R133L, H199A quadruple mutant of PNP-oxidase from E. coli in complex with PLP
Descriptor: FLAVIN MONONUCLEOTIDE, PYRIDOXAL-5'-PHOSPHATE, Pyridoxine/pyridoxamine 5'-phosphate oxidase, ...
Authors:Battista, T, Sularea, M, Barile, A, Fiorillo, A, Tramonti, A, Ilari, A.
Deposit date:2020-04-08
Release date:2021-04-28
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (2.417 Å)
Cite:Identification and characterization of the pyridoxal 5'-phosphate allosteric site in Escherichia coli pyridoxine 5'-phosphate oxidase.
J.Biol.Chem., 296, 2021
2FBM
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BU of 2fbm by Molmil
Acetyltransferase domain of CDY1
Descriptor: CHLORIDE ION, Y chromosome chromodomain protein 1, telomeric isoform b
Authors:Min, J.R, Antoshenko, T, Hong, W, Loppnau, P, Weigelt, J, Sundstrom, M, Arrowsmith, C.H, Edwards, A.M, Bochkarev, A, Plotnikov, A.N, Structural Genomics Consortium (SGC)
Deposit date:2005-12-09
Release date:2005-12-27
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.28 Å)
Cite:Crystal Structure of Acetyltransferases domain of Human Testis-specific chromodomain protein Y 1
To be Published
5ABW
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BU of 5abw by Molmil
Neutrophil elastase inhibitors for the treatment of (cardio)pulmonary diseases
Descriptor: 1-(3-CHLOROPHENYL)-5-(3,5-DIMETHYLISOXAZOL-4-YL)-6-METHYL-N-[4-(METHYLSULFONYL)BENZYL]-2-OXO-1,2-DIHYDROPYRIDINE-3-CARBOXAMIDE, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, ...
Authors:von Nussbaum, F, Li, V.M, Schaefer, M.
Deposit date:2015-08-10
Release date:2015-08-19
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Neutrophil elastase inhibitors for the treatment of (cardio)pulmonary diseases: Into clinical testing with pre-adaptive pharmacophores.
Bioorg. Med. Chem. Lett., 25, 2015
4CJX
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BU of 4cjx by Molmil
The crystal structure of Trypanosoma brucei N5, N10- methylenetetrahydrofolate dehydrogenase-cyclohydrolase (FolD) complexed with NADP cofactor and inhibitor
Descriptor: (2S)-2-[[4-[[2,4-bis(azanyl)-6-oxidanylidene-1H-pyrimidin-5-yl]carbamoylamino]phenyl]carbonylamino]pentanedioic acid, C-1-TETRAHYDROFOLATE SYNTHASE, CYTOPLASMIC, ...
Authors:Eadsforth, T.C, Hunter, W.N.
Deposit date:2013-12-23
Release date:2015-02-04
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:Characterization of 2,4-Diamino-6-Oxo-1,6-Dihydropyrimidin-5-Yl Ureido Based Inhibitors of Trypanosoma Brucei Fold and Testing for Antiparasitic Activity.
J.Med.Chem., 58, 2015
1T76
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BU of 1t76 by Molmil
Crystal structure of the androgen receptor ligand binding domain in complex with a WxxVW motif
Descriptor: 1,2-ETHANEDIOL, 5-ALPHA-DIHYDROTESTOSTERONE, Androgen receptor, ...
Authors:Hur, E, Pfaff, S.J, Payne, E.S, Gron, H, Buehrer, B.M, Fletterick, R.J.
Deposit date:2004-05-08
Release date:2004-08-31
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Recognition and accommodation at the androgen receptor coactivator binding interface.
Plos Biol., 2, 2004
2WP2
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BU of 2wp2 by Molmil
Structure of Brdt bromodomain BD1 bound to a diacetylated histone H4 peptide.
Descriptor: BROMODOMAIN TESTIS-SPECIFIC PROTEIN, HISTONE H4
Authors:Moriniere, J, Rousseaux, S, Steuerwald, U, Soler-Lopez, M, Curtet, S, Vitte, A.-L, Govin, J, Gaucher, J, Sadoul, K, Hart, D.J, Krijgsveld, J, Khochbin, S, Mueller, C.W, Petosa, C.
Deposit date:2009-08-02
Release date:2009-09-22
Last modified:2024-05-01
Method:X-RAY DIFFRACTION (2.37 Å)
Cite:Cooperative Binding of Two Acetylation Marks on a Histone Tail by a Single Bromodomain.
Nature, 461, 2009
2WP1
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BU of 2wp1 by Molmil
Structure of Brdt bromodomain 2 bound to an acetylated histone H3 peptide
Descriptor: BROMODOMAIN TESTIS-SPECIFIC PROTEIN, HISTONE H3
Authors:Moriniere, J, Rousseaux, S, Steuerwald, U, Soler-Lopez, M, Curtet, S, Vitte, A.-L, Govin, J, Gaucher, J, Sadoul, K, Hart, D.J, Krijgsveld, J, Khochbin, S, Mueller, C.W, Petosa, C.
Deposit date:2009-08-02
Release date:2009-09-22
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Cooperative Binding of Two Acetylation Marks on a Histone Tail by a Single Bromodomain.
Nature, 461, 2009
5X9A
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BU of 5x9a by Molmil
Crystal structure of calaxin with calcium
Descriptor: 1,2-ETHANEDIOL, CALCIUM ION, Calaxin
Authors:Shojima, T, Hou, F, Takahashi, Y, Okai, M, Mizuno, K, Inaba, K, Miyakawa, T, Tanokura, M.
Deposit date:2017-03-06
Release date:2018-03-14
Last modified:2024-03-27
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Crystal structure of a Ca2+-dependent regulator of flagellar motility reveals the open-closed structural transition
Sci Rep, 8, 2018
8OTZ
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BU of 8otz by Molmil
48-nm repeat of the native axonemal doublet microtubule from bovine sperm
Descriptor: ATP6V1F neighbor, CFAP97 domain containing 1, Chromosome 13 C20orf85 homolog, ...
Authors:Leung, M.R, Zeng, J, Zhang, R, Zeev-Ben-Mordehai, T.
Deposit date:2023-04-21
Release date:2023-11-22
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:Structural specializations of the sperm tail.
Cell, 186, 2023
8GSV
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BU of 8gsv by Molmil
Crystal structure of human BAK in complex with the Pxt1 BH3 domain
Descriptor: Bcl-2 homologous antagonist/killer, Peroxisomal testis-specific protein 1
Authors:Lim, D, Ku, B.
Deposit date:2022-09-07
Release date:2023-05-10
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structural basis for proapoptotic activation of Bak by the noncanonical BH3-only protein Pxt1.
Plos Biol., 21, 2023
2II2
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BU of 2ii2 by Molmil
Crystal Structure of Alpha-11 Giardin
Descriptor: Alpha-11 giardin, SULFATE ION
Authors:Pathuri, P, Nguyen, E.T, Luecke, H.
Deposit date:2006-09-27
Release date:2007-04-17
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (1.1 Å)
Cite:Apo and Calcium-bound Crystal Structures of Alpha-11 Giardin, an Unusual Annexin from Giardia lamblia
J.Mol.Biol., 368, 2007

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