PDB: 9760 resultsInfo pagesStatus searchChemie searchBIRD

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7T9B	ApexGT5 in complex with GT5-d42.16 and RM20A3 Fabs Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... Authors: Berndsen, Z.T, Ward, A.B. Deposit date: 2021-12-18 Release date: 2022-09-28 Last modified: 2023-07-05 Method: ELECTRON MICROSCOPY (3.72 Å) Cite: Priming HIV Envelope V2 Apex-directed broadly neutralizing antibody responses with protein or mRNA immunogens Immunity, 2022
7T9A	ApexGT2 in complex with GT2-d42.16 and RM20A3 Fabs Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, GT2-d42.16 Fab Heavy Chain, ... Authors: Berndsen, Z.T, Ward, A.B. Deposit date: 2021-12-18 Release date: 2022-09-28 Last modified: 2023-07-05 Method: ELECTRON MICROSCOPY (3.54 Å) Cite: Priming HIV Envelope V2 Apex-directed broadly neutralizing antibody responses with protein or mRNA immunogens Immunity, 2022
7WK5	Cryo-EM structure of Omicron S-ACE2, C2 state Descriptor: Angiotensin-converting enzyme 2, Spike glycoprotein Authors: Han, W.Y, Wang, Y.F. Deposit date: 2022-01-08 Release date: 2022-02-02 Last modified: 2022-03-09 Method: ELECTRON MICROSCOPY (3.66 Å) Cite: Molecular basis of SARS-CoV-2 Omicron variant receptor engagement and antibody evasion and neutralization Biorxiv, 2022
7WK4	Cryo-EM structure of SARS-CoV-2 Omicron spike protein with ACE2, C1 state Descriptor: Angiotensin-converting enzyme 2, Spike glycoprotein Authors: Han, W.Y, Wang, Y.F. Deposit date: 2022-01-08 Release date: 2022-02-02 Last modified: 2022-05-04 Method: ELECTRON MICROSCOPY (3.69 Å) Cite: Molecular basis of receptor binding and antibody neutralization of Omicron Nature, 604, 2022
7WK3	SARS-CoV-2 Omicron S-open Descriptor: Spike glycoprotein Authors: Li, J.W, Cong, Y. Deposit date: 2022-01-08 Release date: 2022-01-26 Method: ELECTRON MICROSCOPY (3.4 Å) Cite: Structural basis for ACE2 engagement and antibody evasion and neutralization of SARS-Co-2 Omicron varient To Be Published
7WK6	Cryo-EM structure of SARS-CoV-2 Omicron spike protein with human ACE2 (focus refinement on RBD-1/ACE2) Descriptor: Angiotensin-converting enzyme 2, Spike glycoprotein Authors: Han, W.Y, Wang, Y.F. Deposit date: 2022-01-08 Release date: 2022-02-02 Last modified: 2022-05-04 Method: ELECTRON MICROSCOPY (3.67 Å) Cite: Molecular basis of receptor binding and antibody neutralization of Omicron Nature, 604, 2022
7WM0	Cryo-EM structure of the Omicron RBD in complex with 35B5 Fab( local refinement of the RBD and 35B5 Fab) Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Heavy chain of 35B5 Fab, Light chain of 35B5 Fab, ... Authors: Wang, X, Zhu, Y. Deposit date: 2022-01-14 Release date: 2022-08-17 Method: ELECTRON MICROSCOPY (3.35 Å) Cite: 35B5 antibody potently neutralizes SARS-CoV-2 Omicron by disrupting the N-glycan switch via a conserved spike epitope Cell Host Microbe, 30, 2022
7WT9	SARS-CoV-2 Omicron variant spike RBD in complex with Fab 9A8 Descriptor: Heavy chain of Fab 9A8, Light chain of Fab 9A8, Spike glycoprotein Authors: Wang, X, Wang, L. Deposit date: 2022-02-04 Release date: 2023-06-07 Method: ELECTRON MICROSCOPY (4.3 Å) Cite: A broader neutralizing antibody against all the current VOCs and VOIs targets unique epitope of SARS-CoV-2 RBD. Cell Discov, 8, 2022
7WT7	SARS-CoV-2 Omicron variant spike in complex with Fab 9A8 (State 1) Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Heavy chain of Fab 9A8, ... Authors: Wang, X, Wang, L. Deposit date: 2022-02-04 Release date: 2023-06-07 Method: ELECTRON MICROSCOPY (3.4 Å) Cite: A broader neutralizing antibody against all the current VOCs and VOIs targets unique epitope of SARS-CoV-2 RBD. Cell Discov, 8, 2022
7WT8	SARS-CoV-2 Omicron variant spike in complex with Fab 9A8 (State 2) Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Heavy chain of Fab 9A8, ... Authors: Wang, X, Wang, L. Deposit date: 2022-02-04 Release date: 2023-06-07 Method: ELECTRON MICROSCOPY (3.6 Å) Cite: A broader neutralizing antibody against all the current VOCs and VOIs targets unique epitope of SARS-CoV-2 RBD. Cell Discov, 8, 2022
7XCK	Cryo-EM structure of SARS-CoV-2 Omicron RBD in complex with S309 fab (local refinement) Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, S309 heavy chain, S309 light chain, ... Authors: Gao, G.F, Qi, J.X, Zhao, Z.N, Xie, Y.F, Liu, S. Deposit date: 2022-03-24 Release date: 2022-08-31 Method: ELECTRON MICROSCOPY (2.5 Å) Cite: Omicron SARS-CoV-2 mutations stabilize spike up-RBD conformation and lead to a non-RBM-binding monoclonal antibody escape Nat Commun, 13, 2022
7XCI	Cryo-EM structure of SARS-CoV-2 Omicron RBD in complex with human ACE2 ectodomain (local refinement) Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Processed angiotensin-converting enzyme 2, ... Authors: Gao, G.F, Qi, J.X, Zhao, Z.N, Liu, S, Xie, Y.F. Deposit date: 2022-03-24 Release date: 2022-08-31 Method: ELECTRON MICROSCOPY (3.2 Å) Cite: Omicron SARS-CoV-2 mutations stabilize spike up-RBD conformation and lead to a non-RBM-binding monoclonal antibody escape Nat Commun, 13, 2022
7XCH	Cryo-EM structure of SARS-CoV-2 Omicron spike protein (S-6P-RRAR) in complex with human ACE2 ectodomain (two-RBD-up state) Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Processed angiotensin-converting enzyme 2, ... Authors: Gao, G.F, Qi, J.X, Zhao, Z.N, Liu, S, Xie, Y.F. Deposit date: 2022-03-24 Release date: 2022-08-31 Method: ELECTRON MICROSCOPY (3.4 Å) Cite: Omicron SARS-CoV-2 mutations stabilize spike up-RBD conformation and lead to a non-RBM-binding monoclonal antibody escape Nat Commun, 13, 2022
7XCP	Cryo-EM structure of Omicron RBD complexed with ACE2 and 304 Fab Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Heavy chain of 304 Fab, ... Authors: Zhao, Z, Qi, J, Gao, F.G. Deposit date: 2022-03-24 Release date: 2022-08-31 Method: ELECTRON MICROSCOPY (3.05 Å) Cite: Omicron SARS-CoV-2 mutations stabilize spike up-RBD conformation and lead to a non-RBM-binding monoclonal antibody escape Nat Commun, 13, 2022
7XCO	Cryo-EM structure of SARS-CoV-2 Omicron spike protein (S-6P-RRAR) in complex with S309 fab Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, S309 Fab heavy chain, ... Authors: Gao, G.F, Qi, J.X, Zhao, Z.N, Liu, S, Xie, Y.F. Deposit date: 2022-03-24 Release date: 2022-09-21 Method: ELECTRON MICROSCOPY (2.5 Å) Cite: Omicron SARS-CoV-2 mutations stabilize spike up-RBD conformation and lead to a non-RBM-binding monoclonal antibody escape Nat Commun, 13, 2022
7XCA	Crystal structure of the porcine astrovirus capsid spike domain Descriptor: CHLORIDE ION, Capsid protein spike domain, MAGNESIUM ION Authors: Pan, L.X, Zhang, W.C, Yang, D.F, Yang, L.Y, Liu, H. Deposit date: 2022-03-23 Release date: 2023-03-29 Last modified: 2024-05-29 Method: X-RAY DIFFRACTION (2.5 Å) Cite: Crystal structure analysis of porcine astrovirus capsid spike and spike/neutralizing antibody complexes. To Be Published
8EPA	Structure of interleukin receptor common gamma chain (IL2Rgamma) in complex with two antibodies Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Cytokine receptor common subunit gamma, REGN7257 Fab heavy chain, ... Authors: Franklin, M.C, Romero Hernandez, A. Deposit date: 2022-10-05 Release date: 2023-01-25 Method: ELECTRON MICROSCOPY (3.4 Å) Cite: Blocking common gamma chain cytokine signaling ameliorates T cell-mediated pathogenesis in disease models. Sci Transl Med, 15, 2023
7Y7J	SARS-CoV-2 S trimer in complex with 1F Fab Descriptor: 1F VH, 1F VL, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... Authors: Zhao, S, Liu, F, Yang, X, Zhong, G. Deposit date: 2022-06-22 Release date: 2023-02-22 Method: ELECTRON MICROSCOPY (4.8 Å) Cite: A core epitope targeting antibody of SARS-CoV-2. Protein Cell, 14, 2023
7EH5	Cryo-EM structure of SARS-CoV-2 S-D614G variant in complex with neutralizing antibodies, RBD-chAb15 and RBD-chAb45 Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, RBD-chAb15, ... Authors: Yang, T.J, Yu, P.Y, Chang, Y.C, Wu, H.C, Hsu, S.T.D. Deposit date: 2021-03-28 Release date: 2021-09-01 Last modified: 2022-01-05 Method: ELECTRON MICROSCOPY (4 Å) Cite: Effect of SARS-CoV-2 B.1.1.7 mutations on spike protein structure and function. Nat.Struct.Mol.Biol., 28, 2021
7YZJ	FAB IN COMPLEX WITH ANTIGENIC PEPTIDE OF INTERLEUKIN-2 Descriptor: Antigenic peptide, Heavy chain of FAB fragment, Light chain of FAB fragment Authors: Pletnev, V, Pletneva, N. Deposit date: 2022-02-20 Release date: 2023-02-01 Last modified: 2024-02-07 Method: X-RAY DIFFRACTION (2.6 Å) Cite: Three-Dimensional Structure of Fab Fragment of Monoclonal Antibody LNKB-2 Complexed with Antigenic Nonapeptide from Human Interleukin-2 Russ.J.Bioorganic Chem., 2023
7Y7K	SARS-CoV-2 RBD in complex with 1F Fab Descriptor: 1F VH, 1F VL, Spike protein S1 Authors: Zhao, S, Liu, F, Yang, X, Zhong, G. Deposit date: 2022-06-22 Release date: 2023-02-22 Method: ELECTRON MICROSCOPY (4.4 Å) Cite: A core epitope targeting antibody of SARS-CoV-2. Protein Cell, 14, 2023
8TFN	Structure of anti-TCRvbeta6-5 antibody in complex with the cognate TCR Descriptor: Anti-TCRVb6-5 Fab heavy chain, Anti-TCRVb6-5 Fab light chain, TRAV12-3, ... Authors: Katragadda, M, Servatalab, R, Wirth, J. Deposit date: 2023-07-11 Release date: 2023-11-08 Last modified: 2024-05-22 Method: X-RAY DIFFRACTION (2.54 Å) Cite: Innate TCR beta-chain engagement drives human T cells toward distinct memory-like effector phenotypes with immunotherapeutic potentials. Sci Adv, 9, 2023
7M6D	Structure of the SARS-CoV-2 RBD in complex with neutralizing antibodies BG4-25 and CR3022 Descriptor: BG4-25 Fab Heavy Chain, BG4-25 Fab Light Chain, CR3022 Fab Heavy Chain, ... Authors: Barnes, C.O, Bjorkman, P.J. Deposit date: 2021-03-25 Release date: 2021-05-05 Last modified: 2023-10-18 Method: X-RAY DIFFRACTION (3.1 Å) Cite: B cell genomics behind cross-neutralization of SARS-CoV-2 variants and SARS-CoV. Cell, 184, 2021
7PA8	JC polyomavirus VP1 in complex with Fab 27C2 Descriptor: Fab 27C2 heavy chain, Fab 27C2 light chain, Major capsid protein VP1 Authors: Stroeh, L.J, Harprecht, C, Freytag, J, Stehle, T. Deposit date: 2021-07-29 Release date: 2023-02-08 Last modified: 2024-02-07 Method: X-RAY DIFFRACTION (3.15 Å) Cite: Structural characterization of human neutralizing antibodies against JC and BK polyomavirus To Be Published
7PAA	JC polyomavirus VP1 in complex with scFv 29B1 Descriptor: Major capsid protein VP1, scFv 29B1 Authors: Harprecht, C, Stroeh, L.J, Freytag, J, Stehle, T. Deposit date: 2021-07-29 Release date: 2023-02-08 Last modified: 2024-02-07 Method: X-RAY DIFFRACTION (3.102 Å) Cite: Structural characterization of human neutralizing antibodies against JC and BK polyomavirus To Be Published

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