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7XCO

Cryo-EM structure of SARS-CoV-2 Omicron spike protein (S-6P-RRAR) in complex with S309 fab

Summary for 7XCO
Entry DOI10.2210/pdb7xco/pdb
EMDB information33124
DescriptorSpike glycoprotein, S309 Fab heavy chain, S309 fab light chain, ... (5 entities in total)
Functional Keywordsomicron, spike, sars-cov-2, s309, viral protein
Biological sourceSevere acute respiratory syndrome coronavirus 2
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Total number of polymer chains9
Total formula weight571847.77
Authors
Gao, G.F.,Qi, J.X.,Zhao, Z.N.,Liu, S.,Xie, Y.F. (deposition date: 2022-03-24, release date: 2022-09-21)
Primary citationZhao, Z.,Zhou, J.,Tian, M.,Huang, M.,Liu, S.,Xie, Y.,Han, P.,Bai, C.,Han, P.,Zheng, A.,Fu, L.,Gao, Y.,Peng, Q.,Li, Y.,Chai, Y.,Zhang, Z.,Zhao, X.,Song, H.,Qi, J.,Wang, Q.,Wang, P.,Gao, G.F.
Omicron SARS-CoV-2 mutations stabilize spike up-RBD conformation and lead to a non-RBM-binding monoclonal antibody escape
Nat Commun, 13:4958-, 2022
Cited by
DOI: 10.1038/s41467-022-32665-7
PDB entries with the same primary citation
Experimental method
ELECTRON MICROSCOPY (2.5 Å)
Structure validation

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