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1YBO
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Crystal structure of the PDZ tandem of human syntenin with syndecan peptide
Descriptor: Syndecan-4, Syntenin 1
Authors:Grembecka, J, Cooper, D.R, Cierpicki, T, Kang, B.S, Devedjiev, Y, Derewenda, Z.
Deposit date:2004-12-21
Release date:2006-01-10
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:The binding of the PDZ tandem of syntenin to target proteins
Biochemistry, 45, 2006
1Y7N
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Solution structure of the second PDZ domain of the human neuronal adaptor X11alpha
Descriptor: Amyloid beta A4 precursor protein-binding family A member 1
Authors:Duquesne, A.E, de Ruijter, M, Brouwer, J, Drijfhout, J.W, Nabuurs, S.B, Spronk, C.A.E.M, Vuister, G.W, Ubbink, M, Canters, G.W.
Deposit date:2004-12-09
Release date:2005-11-22
Last modified:2022-03-02
Method:SOLUTION NMR
Cite:Solution structure of the second PDZ domain of the neuronal adaptor X11alpha and its interaction with the C-terminal peptide of the human copper chaperone for superoxide dismutase
J.Biomol.Nmr, 32, 2005
7W6X
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BU of 7w6x by Molmil
Crystal structure of E. coli RseP in complex with batimastat
Descriptor: 4-(N-HYDROXYAMINO)-2R-ISOBUTYL-2S-(2-THIENYLTHIOMETHYL)SUCCINYL-L-PHENYLALANINE-N-METHYLAMIDE, Regulator of sigma-E protease RseP, ZINC ION
Authors:Takanuki, K, Imaizumi, Y, Nogi, T.
Deposit date:2021-12-02
Release date:2022-09-07
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Mechanistic insights into intramembrane proteolysis by E. coli site-2 protease homolog RseP.
Sci Adv, 8, 2022
4WSI
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BU of 4wsi by Molmil
Crystal Structure of PALS1/Crb complex
Descriptor: MAGUK p55 subfamily member 5, Protein crumbs
Authors:Wei, Z, Li, Y, Zhang, M.
Deposit date:2014-10-28
Release date:2014-11-26
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (2.95 Å)
Cite:Structure of Crumbs tail in complex with the PALS1 PDZ-SH3-GK tandem reveals a highly specific assembly mechanism for the apical Crumbs complex.
Proc.Natl.Acad.Sci.USA, 111, 2014
4A9G
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BU of 4a9g by Molmil
Symmetrized cryo-EM reconstruction of E. coli DegQ 24-mer in complex with beta-casein
Descriptor: PERIPLASMIC PH-DEPENDENT SERINE ENDOPROTEASE DEGQ
Authors:Malet, H, Canellas, F, Sawa, J, Yan, J, Thalassinos, K, Ehrmann, M, Clausen, T, Saibil, H.R.
Deposit date:2011-11-26
Release date:2012-01-11
Last modified:2017-08-23
Method:ELECTRON MICROSCOPY (7.5 Å)
Cite:Newly Folded Substrates Inside the Molecular Cage of the Htra Chaperone Degq
Nat.Struct.Mol.Biol., 19, 2012
4A8C
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Symmetrized cryo-EM reconstruction of E. coli DegQ 12-mer in complex with a binding peptide
Descriptor: PERIPLASMIC PH-DEPENDENT SERINE ENDOPROTEASE DEGQ
Authors:Malet, H, Canellas, F, Sawa, J, Yan, J, Thalassinos, K, Ehrmann, M, Clausen, T, Saibil, H.R.
Deposit date:2011-11-20
Release date:2012-01-11
Last modified:2017-08-30
Method:ELECTRON MICROSCOPY (7.5 Å)
Cite:Newly Folded Substrates Inside the Molecular Cage of the Htra Chaperone Degq
Nat.Struct.Mol.Biol., 19, 2012
5V6T
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BU of 5v6t by Molmil
The Plexin D1 intracellular region in complex with GIPC1
Descriptor: PDZ domain-containing protein GIPC1, Plexin-D1, SULFATE ION
Authors:Shang, G, Zhang, X.
Deposit date:2017-03-17
Release date:2017-05-31
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (3.189 Å)
Cite:Structure analyses reveal a regulated oligomerization mechanism of the PlexinD1/GIPC/myosin VI complex.
Elife, 6, 2017
5WQL
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Structure of a PDZ-protease bound to a substrate-binding adaptor
Descriptor: ALA-ALA-ALA-ALA, ALA-ALA-ALA-ALA-ALA-ALA, LEU-SER-ARG-SER, ...
Authors:Su, M.Y, Chang, C.I.
Deposit date:2016-11-27
Release date:2017-11-22
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structural basis of adaptor-mediated protein degradation by the tail-specific PDZ-protease Prc
Nat Commun, 8, 2017
4QL6
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Structure of C. trachomatis CT441
Descriptor: Carboxy-terminal processing protease
Authors:Kohlmann, F, Hilgenfeld, R, Hansen, G.
Deposit date:2014-06-10
Release date:2014-11-05
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (2.97 Å)
Cite:Structural basis of the proteolytic and chaperone activity of Chlamydia trachomatis CT441
J.Bacteriol., 197, 2015
3SHW
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BU of 3shw by Molmil
Crystal structure of ZO-1 PDZ3-SH3-Guk supramodule complex with Connexin-45 peptide
Descriptor: Gap junction gamma-1 protein, Tight junction protein ZO-1
Authors:Yu, J, Pan, L, Chen, J, Yu, H, Zhang, M.
Deposit date:2011-06-17
Release date:2011-09-28
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:The Structure of the PDZ3-SH3-GuK Tandem of ZO-1 Suggests a Supramodular Organization of the Conserved MAGUK Family Scaffold Core
To be Published
3STJ
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BU of 3stj by Molmil
Crystal structure of the protease + PDZ1 domain of DegQ from Escherichia coli
Descriptor: Protease degQ, peptide (UNK)
Authors:Sawa, J, Malet, H, Krojer, T, Canellas, F, Ehrmann, M, Clausen, T.
Deposit date:2011-07-11
Release date:2011-07-27
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Molecular adaptation of the DegQ protease to exert protein quality control in the bacterial cell envelope.
J.Biol.Chem., 286, 2011
3SUZ
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BU of 3suz by Molmil
Crystal structure of Rat Mint2 PPC
Descriptor: Amyloid beta A4 precursor protein-binding family A member 2
Authors:Shen, Y, Long, J, Yan, X, Xie, X.
Deposit date:2011-07-11
Release date:2012-07-11
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Open-closed motion of Mint2 regulates APP metabolism
J Mol Cell Biol, 5, 2013
6SAK
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BU of 6sak by Molmil
Structure of the OTULINcat C129A - SNX27 PDZ domain complex.
Descriptor: GLYCEROL, SULFATE ION, Sorting nexin-27, ...
Authors:Elliott, P.R, Komander, D.
Deposit date:2019-07-17
Release date:2019-10-02
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (2 Å)
Cite:Regulation of the endosomal SNX27-retromer by OTULIN.
Nat Commun, 10, 2019
3TMH
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BU of 3tmh by Molmil
Crystal structure of dual-specific A-kinase anchoring protein 2 in complex with cAMP-dependent protein kinase A type II alpha and PDZK1
Descriptor: A-kinase anchor protein 10, mitochondrial, Na(+)/H(+) exchange regulatory cofactor NHE-RF3, ...
Authors:Sarma, G.N, Phan, R.H, Sankaran, B, Taylor, S.S.
Deposit date:2011-08-31
Release date:2012-09-05
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (3.8 Å)
Cite:Differential mode of D-AKAP2 to PKA isoforms: Insights from D-AKAP2 PKA RII PDZK1 ternary complex structure
To be Published
3TSZ
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BU of 3tsz by Molmil
crystal structure of PDZ3-SH3-GUK core module from human ZO-1 in complex with 12mer peptide from human JAM-A cytoplasmic tail
Descriptor: Junctional adhesion molecule A, Tight junction protein ZO-1
Authors:Nomme, J, Lavie, A.
Deposit date:2011-09-13
Release date:2011-10-12
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.502 Å)
Cite:The Src Homology 3 Domain Is Required for Junctional Adhesion Molecule Binding to the Third PDZ Domain of the Scaffolding Protein ZO-1.
J.Biol.Chem., 286, 2011
3TSW
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BU of 3tsw by Molmil
crystal structure of the PDZ3-SH3-GUK core module of Human ZO-1
Descriptor: SULFATE ION, Tight junction protein ZO-1
Authors:Nomme, J, Lavie, A.
Deposit date:2011-09-13
Release date:2011-10-12
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.847 Å)
Cite:The Src Homology 3 Domain Is Required for Junctional Adhesion Molecule Binding to the Third PDZ Domain of the Scaffolding Protein ZO-1.
J.Biol.Chem., 286, 2011
1KY9
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BU of 1ky9 by Molmil
Crystal Structure of DegP (HtrA)
Descriptor: PROTEASE DO
Authors:Krojer, T, Garrido-Franco, M, Huber, R, Ehrmann, M, Clausen, T.
Deposit date:2002-02-04
Release date:2002-04-03
Last modified:2021-10-27
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Crystal structure of DegP (HtrA) reveals a new protease-chaperone machine.
Nature, 416, 2002
6IQQ
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BU of 6iqq by Molmil
Crystal structure of Prc with S452I and L252Y mutations in complex with NlpI
Descriptor: CALCIUM ION, Lipoprotein NlpI, Tail-specific protease
Authors:Chueh, C.K, Chang, C.I.
Deposit date:2018-11-08
Release date:2019-07-24
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structural Basis for the Differential Regulatory Roles of the PDZ Domain in C-Terminal Processing Proteases.
Mbio, 10, 2019
6IRD
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BU of 6ird by Molmil
Complex structure of INADL PDZ89 and PLCb4 C-terminal CC-PBM
Descriptor: 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase, GOLD ION, InaD-like protein
Authors:Ye, F, Li, J, Huang, Y, Liu, W, Zhang, M.
Deposit date:2018-11-12
Release date:2019-01-23
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.813 Å)
Cite:An unexpected INAD PDZ tandem-mediated plc beta binding in Drosophila photo receptors.
Elife, 7, 2018
6IRE
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BU of 6ire by Molmil
Complex structure of INAD PDZ45 and NORPA CC-PBM
Descriptor: 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase, Inactivation-no-after-potential D protein
Authors:Ye, F, Li, J, Deng, X, Liu, W, Zhang, M.
Deposit date:2018-11-12
Release date:2019-01-23
Last modified:2024-03-27
Method:X-RAY DIFFRACTION (3.25 Å)
Cite:An unexpected INAD PDZ tandem-mediated plc beta binding in Drosophila photo receptors.
Elife, 7, 2018
6IQR
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BU of 6iqr by Molmil
Crystal structure of Prc with S452I and L252Y mutations
Descriptor: Tail-specific protease
Authors:Chueh, C.K, Chang, C.I.
Deposit date:2018-11-08
Release date:2019-07-24
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (3.42 Å)
Cite:Structural Basis for the Differential Regulatory Roles of the PDZ Domain in C-Terminal Processing Proteases.
Mbio, 10, 2019
6IQS
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BU of 6iqs by Molmil
Crystal structure of Prc with L245A and L340G mutations in complex with NlpI
Descriptor: Lipoprotein NlpI, Tail-specific protease
Authors:Chuech, C.K, Chang, C.I.
Deposit date:2018-11-08
Release date:2019-07-24
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.69 Å)
Cite:Structural Basis for the Differential Regulatory Roles of the PDZ Domain in C-Terminal Processing Proteases.
Mbio, 10, 2019
6JJL
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BU of 6jjl by Molmil
Crystal structure of the DegP dodecamer with a modulator
Descriptor: CYS-TYR-ARG-LYS-LEU, Periplasmic serine endoprotease DegP
Authors:Cho, H, Choi, Y, Lee, H.H, Kim, S.
Deposit date:2019-02-26
Release date:2020-09-02
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (4.2 Å)
Cite:Over-activation of a nonessential bacterial protease DegP as an antibiotic strategy.
Commun Biol, 3, 2020
6JJK
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BU of 6jjk by Molmil
Crystal structure of the DegP dodecamer with a modulator
Descriptor: CYS-TYR-TYR-LYS-ILE, Periplasmic serine endoprotease DegP
Authors:Cho, H, Choi, Y, Lee, H.H, Kim, S.
Deposit date:2019-02-26
Release date:2020-09-02
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (3.6 Å)
Cite:Over-activation of a nonessential bacterial protease DegP as an antibiotic strategy
Commun Biol, 3, 2020
6JJO
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BU of 6jjo by Molmil
Crystal structure of the DegP dodecamer with a modulator
Descriptor: Periplasmic serine endoprotease DegP, TMB-CYRKL modulator
Authors:Cho, H, Choi, Y, Lee, H.H, Kim, S.
Deposit date:2019-02-26
Release date:2020-09-02
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (4.157 Å)
Cite:Over-activation of a nonessential bacterial protease DegP as an antibiotic strategy
Commun Biol, 3, 2020

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