7W6X

Crystal structure of E. coli RseP in complex with batimastat

Summary for 7W6X

Entry DOI	10.2210/pdb7w6x/pdb
Descriptor	Regulator of sigma-E protease RseP, ZINC ION, 4-(N-HYDROXYAMINO)-2R-ISOBUTYL-2S-(2-THIENYLTHIOMETHYL)SUCCINYL-L-PHENYLALANINE-N-METHYLAMIDE (3 entities in total)
Functional Keywords	intramembrane protease, hydrolase
Biological source	Escherichia coli
Total number of polymer chains	1
Total formula weight	50711.50
Authors	Takanuki, K.,Imaizumi, Y.,Nogi, T. (deposition date: 2021-12-02, release date: 2022-09-07)
Primary citation	Imaizumi, Y.,Takanuki, K.,Miyake, T.,Takemoto, M.,Hirata, K.,Hirose, M.,Oi, R.,Kobayashi, T.,Miyoshi, K.,Aruga, R.,Yokoyama, T.,Katagiri, S.,Matsuura, H.,Iwasaki, K.,Kato, T.,Kaneko, M.K.,Kato, Y.,Tajiri, M.,Akashi, S.,Nureki, O.,Hizukuri, Y.,Akiyama, Y.,Nogi, T. Mechanistic insights into intramembrane proteolysis by E. coli site-2 protease homolog RseP. Sci Adv, 8:eabp9011-eabp9011, 2022 Cited by PubMed: 36001659 DOI: 10.1126/sciadv.abp9011 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (3.2 Å)

Structure validation