Crystal structure of the PDZ tandem of human syntenin with syndecan peptide

Summary for 1YBO

DescriptorSyntenin 1, Syndecan-4 (3 entities in total)
Functional Keywordspdz domain, scaffolding protein, adhesion complex, structural protein
Biological sourceHomo sapiens (human)
Cellular locationCell junction, focal adhesion  O00560
Isoform 1: Membrane ; Single- pass type I membrane protein . Isoform 2: Secreted P31431
Total number of polymer chains4
Total molecular weight39982.03
Grembecka, J.,Cooper, D.R.,Cierpicki, T.,Kang, B.S.,Devedjiev, Y.,Derewenda, Z. (deposition date: 2004-12-21, release date: 2006-01-10, Last modification date: 2017-10-11)
Primary citation
Grembecka, J.,Cierpicki, T.,Devedjiev, Y.,Derewenda, U.,Kang, B.S.,Bushweller, J.H.,Derewenda, Z.S.
The binding of the PDZ tandem of syntenin to target proteins
Biochemistry, 45:3674-3683, 2006
PubMed: 16533050 (PDB entries with the same primary citation)
DOI: 10.1021/bi052225y
MImport into Mendeley
Experimental method
NMR Information

Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.29141.2%2.4%3.0%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution