8TH6
| Crystal Structure of the G3BP1 NTF2-like domain bound to USP10 peptide | Descriptor: | 1,2-ETHANEDIOL, Ras GTPase-activating protein-binding protein 1, Ubiquitin carboxyl-terminal hydrolase 10 | Authors: | Hughes, M.P, Taylor, J.P, Yang, Z. | Deposit date: | 2023-07-14 | Release date: | 2024-03-20 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (2.34 Å) | Cite: | Interaction between host G3BP and viral nucleocapsid protein regulates SARS-CoV-2 replication and pathogenicity. Cell Rep, 43, 2024
|
|
6DJ9
| Structure of the USP15 DUSP domain in complex with a high-affinity Ubiquitin Variant (UbV) | Descriptor: | Ubiquitin Variant UbV 15.D, Ubiquitin carboxyl-terminal hydrolase 15 | Authors: | Singer, A.U, Teyra, J, Boehmelt, G, Lenter, M, Sicheri, F, Sidhu, S.S. | Deposit date: | 2018-05-24 | Release date: | 2019-01-23 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (3.1 Å) | Cite: | Structural and Functional Characterization of Ubiquitin Variant Inhibitors of USP15. Structure, 27, 2019
|
|
5CHV
| Crystal structure of USP18-ISG15 complex | Descriptor: | CHLORIDE ION, SULFATE ION, Ubiquitin-like protein ISG15, ... | Authors: | Fritz, G, Basters, A. | Deposit date: | 2015-07-10 | Release date: | 2016-09-28 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (3.005 Å) | Cite: | Structural basis of the specificity of USP18 toward ISG15. Nat. Struct. Mol. Biol., 24, 2017
|
|
2AYO
| Structure of USP14 bound to ubquitin aldehyde | Descriptor: | Ubiquitin, Ubiquitin carboxyl-terminal hydrolase 14 | Authors: | Hu, M, Li, P, Jeffrey, P.D, Shi, Y. | Deposit date: | 2005-09-07 | Release date: | 2005-10-18 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (3.5 Å) | Cite: | Structure and mechanisms of the proteasome-associated deubiquitinating enzyme USP14. Embo J., 24, 2005
|
|
5CHT
| Crystal structure of USP18 | Descriptor: | Ubl carboxyl-terminal hydrolase 18, ZINC ION | Authors: | Fritz, G, Basters, A. | Deposit date: | 2015-07-10 | Release date: | 2016-06-29 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Structural basis of the specificity of USP18 toward ISG15. Nat. Struct. Mol. Biol., 24, 2017
|
|
4A3P
| Structure of USP15 DUSP-UBL deletion mutant | Descriptor: | ACETATE ION, IODIDE ION, UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 15 | Authors: | Elliott, P.R, Liu, H, Pastok, M.W, Grossmann, G.J, Rigden, D.J, Clague, M.J, Urbe, S, Barsukov, I.L. | Deposit date: | 2011-10-03 | Release date: | 2011-11-16 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (1.4 Å) | Cite: | Structural Variability of the Ubiquitin Specific Protease Dusp-Ubl Double Domains. FEBS Lett., 585, 2011
|
|
3PV1
| Crystal structure of the USP15 DUSP-UBL domains | Descriptor: | ACETATE ION, Ubiquitin carboxyl-terminal hydrolase 15 | Authors: | Elliott, P.R, Urbe, S, Clague, M.J, Barsukov, I.L. | Deposit date: | 2010-12-06 | Release date: | 2011-11-16 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Structural variability of the ubiquitin specific protease DUSP-UBL double domains. Febs Lett., 585, 2011
|
|
8OYP
| Crystal structure of Ubiquitin specific protease 11 (USP11) in complex with a substrate mimetic | Descriptor: | CADMIUM ION, CHLORIDE ION, GLYCEROL, ... | Authors: | Maurer, S.K, Caulton, S.G, Ward, S.J, Emsley, J, Dreveny, I. | Deposit date: | 2023-05-05 | Release date: | 2023-10-18 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (2.44 Å) | Cite: | Ubiquitin-specific protease 11 structure in complex with an engineered substrate mimetic reveals a molecular feature for deubiquitination selectivity. J.Biol.Chem., 299, 2023
|
|
8WG5
| Cryo-EM structure of USP16 bound to H2AK119Ub nucleosome | Descriptor: | DNA (147-MER), Histone H2A type 1-B/E, Histone H2B type 1-K, ... | Authors: | Ai, H.S, He, Z.Z, Deng, Z.H, Liu, L. | Deposit date: | 2023-09-20 | Release date: | 2023-12-27 | Last modified: | 2024-07-10 | Method: | ELECTRON MICROSCOPY (3.05 Å) | Cite: | Structural and mechanistic basis for nucleosomal H2AK119 deubiquitination by single-subunit deubiquitinase USP16. Nat.Struct.Mol.Biol., 2024
|
|
4A3O
| Crystal structure of the USP15 DUSP-UBL monomer | Descriptor: | GLYCEROL, UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 15 | Authors: | Elliott, P.R, Liu, H, Pastok, M.W, Grossmann, G.J, Rigden, D.J, Clague, M.J, Urbe, S, Barsukov, I.L. | Deposit date: | 2011-10-03 | Release date: | 2011-11-16 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Structural Variability of the Ubiquitin Specific Protease Dusp-Ubl Double Domains. FEBS Lett., 585, 2011
|
|
6CRN
| Structure of the USP15 deubiquitinase domain in complex with a high-affinity first-generation Ubv | Descriptor: | Ubiquitin carboxyl-terminal hydrolase 15, Ubiquitin variant 15.2, ZINC ION | Authors: | Singer, A.U, Teyra, J, Boehmelt, G, Lenter, M, Sicheri, F, Sidhu, S.S. | Deposit date: | 2018-03-19 | Release date: | 2019-01-23 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Structural and Functional Characterization of Ubiquitin Variant Inhibitors of USP15. Structure, 27, 2019
|
|
6CPM
| Structure of the USP15 deubiquitinase domain in complex with a third-generation inhibitory Ubv | Descriptor: | 1,2-ETHANEDIOL, CALCIUM ION, GLYCEROL, ... | Authors: | Singer, A.U, Teyra, J, Boehmelt, G, Lenter, M, Sicheri, F, Sidhu, S.S. | Deposit date: | 2018-03-13 | Release date: | 2019-01-23 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (2.011 Å) | Cite: | Structural and Functional Characterization of Ubiquitin Variant Inhibitors of USP15. Structure, 27, 2019
|
|
2AYN
| Structure of USP14, a proteasome-associated deubiquitinating enzyme | Descriptor: | Ubiquitin carboxyl-terminal hydrolase 14 | Authors: | Hu, M, Li, P, Jeffrey, P.D, Shi, Y. | Deposit date: | 2005-09-07 | Release date: | 2005-10-18 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (3.2 Å) | Cite: | Structure and mechanisms of the proteasome-associated deubiquitinating enzyme USP14. Embo J., 24, 2005
|
|
2LBC
| solution structure of tandem UBA of USP13 | Descriptor: | Ubiquitin carboxyl-terminal hydrolase 13 | Authors: | Zhang, Y, Zhou, C, Zhou, Z, Song, A, Hu, H. | Deposit date: | 2011-03-29 | Release date: | 2012-03-07 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | Domain Analysis Reveals That a Deubiquitinating Enzyme USP13 Performs Non-Activating Catalysis for Lys63-Linked Polyubiquitin. Plos One, 6, 2011
|
|
2L80
| Solution Structure of the Zinc Finger Domain of USP13 | Descriptor: | Ubiquitin carboxyl-terminal hydrolase 13, ZINC ION | Authors: | Zhang, Y, Zhou, C, Zhou, Z, Song, A, Hu, H. | Deposit date: | 2010-12-28 | Release date: | 2011-12-14 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | Biochemical Characterization of the Ubiquitin Receptors in USP13 Reveals Different Catalytic Activation of Deubiquitination from Its Analogue USP5 To be Published
|
|
6KHV
| Solution Structure of the CS2 Domain of USP19 | Descriptor: | Ubiquitin carboxyl-terminal hydrolase 19 | Authors: | Xue, W, Hu, H.Y. | Deposit date: | 2019-07-16 | Release date: | 2020-07-22 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | Domain interactions reveal auto-inhibition of the deubiquitinating enzyme USP19 and its activation by HSP90 in the modulation of huntingtin aggregation. Biochem.J., 477, 2020
|
|
6ML1
| Structure of the USP15 deubiquitinase domain in complex with an affinity-matured inhibitory Ubv | Descriptor: | 1,2-ETHANEDIOL, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CALCIUM ION, ... | Authors: | Singer, A.U, Teyra, J, Boehmelt, G, Lenter, M, Sicheri, F, Sidhu, S.S. | Deposit date: | 2018-09-26 | Release date: | 2019-01-23 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Structural and Functional Characterization of Ubiquitin Variant Inhibitors of USP15. Structure, 27, 2019
|
|
6LVS
| |
6KQV
| Solution Structure of the UbL Domain of USP19 | Descriptor: | Ubiquitin carboxyl-terminal hydrolase 19 | Authors: | Xue, W, Hu, H.Y. | Deposit date: | 2019-08-19 | Release date: | 2020-08-19 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | Domain interactions reveal auto-inhibition of the deubiquitinating enzyme USP19 and its activation by HSP90 in the modulation of huntingtin aggregation. Biochem.J., 477, 2020
|
|
6K7W
| Solution Structure of the CS1 Domain of USP19 | Descriptor: | Ubiquitin carboxyl-terminal hydrolase 19 | Authors: | Xue, W, Hu, H.Y. | Deposit date: | 2019-06-10 | Release date: | 2020-06-10 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | Domain interactions reveal auto-inhibition of the deubiquitinating enzyme USP19 and its activation by HSP90 in the modulation of huntingtin aggregation. Biochem.J., 477, 2020
|
|
5JJW
| Crystal structure of the HAT domain of sart3 in complex with USP15 DUSP-UBL domain | Descriptor: | 1,2-ETHANEDIOL, Squamous cell carcinoma antigen recognized by T-cells 3, UNKNOWN ATOM OR ION, ... | Authors: | Dong, A, Zhang, Q, Walker, J.R, Bountra, C, Arrowsmith, C.H, Edwards, A.M, Tong, Y, Structural Genomics Consortium (SGC) | Deposit date: | 2016-04-25 | Release date: | 2016-05-04 | Last modified: | 2016-07-06 | Method: | X-RAY DIFFRACTION (3.01 Å) | Cite: | Crystal structure of the HAT domain of sart3 in complex with USP15 DUSP-UBL domain to be published
|
|
5K1A
| |
5K16
| |
5K1C
| Crystal structure of the UAF1/WDR20/USP12 complex | Descriptor: | PHOSPHATE ION, TRIS(HYDROXYETHYL)AMINOMETHANE, Ubiquitin carboxyl-terminal hydrolase 12, ... | Authors: | Li, H, D'Andrea, A.D, Zheng, N. | Deposit date: | 2016-05-18 | Release date: | 2016-07-20 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Allosteric Activation of Ubiquitin-Specific Proteases by beta-Propeller Proteins UAF1 and WDR20. Mol.Cell, 63, 2016
|
|
5K1B
| |